Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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Cadherin Peptide, avian Acetate
<p>Cadherin Peptide, avian Acetate: a type-1 transmembrane protein sequence LRAHAVDVNG-NH2.</p>Formula:C46H79N17O15Purity:97.69%Color and Shape:SolidMolecular weight:1110.22Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formula:C30H28FN7O3Purity:99.53% - 99.79%Color and Shape:SolidMolecular weight:553.59Benproperine phosphate
CAS:<p>Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.</p>Formula:C21H30NO5PPurity:99.84%Color and Shape:PowderMolecular weight:407.44HSP70-IN-1
CAS:<p>HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).</p>Formula:C24H28N6O2SPurity:99.91%Color and Shape:SolidMolecular weight:464.58HSDVHK-NH2 acetate
<p>P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).</p>Formula:C32H52N12O11Purity:99.5%Color and Shape:SolidMolecular weight:780.39Bisindolylmaleimide I
CAS:<p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>Formula:C25H24N4O2Purity:98.19% - 98.75%Color and Shape:Orange SolidMolecular weight:412.48Valrubicin
CAS:<p>Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.</p>Formula:C34H36F3NO13Purity:98.63%Color and Shape:SolidMolecular weight:723.644-Isopropoxybenzoic acid
CAS:<p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>Formula:C10H12O3Purity:99.88%Color and Shape:White To Off-White PowderMolecular weight:180.2Rotigaptide TFA(355151-12-1 free base)
<p>Rotigaptide TFA is a Cx43 modulator & AAP that maintains gap junctions & cell communication under stress.</p>Formula:C30H40F3N7O11Purity:99.21%Color and Shape:SolidMolecular weight:731.67Parbendazole
CAS:<p>Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.</p>Formula:C13H17N3O2Purity:99.60%Color and Shape:Physical Description Crystals Or Fine White Powder (Ntp 1992)Molecular weight:247.29Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formula:C32H46O8Purity:97.1% - 99.33%Color and Shape:SolidMolecular weight:558.7SB-743921 hydrochloride
CAS:<p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>Formula:C31H34Cl2N2O3Purity:95.58% - 99.70%Color and Shape:SolidMolecular weight:553.52KY-02327
CAS:<p>KY-02327: Stabilized KY-02061 analog, inhibits Dvl-CXXC5, activates Wnt/β-catenin, and promotes osteoblast differentiation.</p>Formula:C20H27N3O4Purity:97.04%Color and Shape:SolidMolecular weight:373.45Wiskostatin
CAS:<p>Wiskostatin selectively inhibits N-WASP, key in actin polymerization, linked to Wiskott-Aldrich Syndrome.</p>Formula:C17H18Br2N2OPurity:99.84% - 99.97%Color and Shape:White SolidMolecular weight:426.15AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formula:C14H13BrN2OPurity:98% - 99.37%Color and Shape:SolidMolecular weight:305.17DTHIB
CAS:<p>DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.</p>Formula:C13H9ClFN3O3Purity:98.86% - 99.29%Color and Shape:SolidMolecular weight:309.68Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Questiomycin A
CAS:<p>Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.</p>Formula:C12H8N2O2Purity:98.13% - 98.7%Color and Shape:SolidMolecular weight:212.2Teprenone
CAS:<p>Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).</p>Formula:C23H38OPurity:99.1% - 99.96%Color and Shape:SolidMolecular weight:330.55Afuresertib
CAS:<p>Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic</p>Formula:C18H17Cl2FN4OSPurity:97.51% - 99.51%Color and Shape:SolidMolecular weight:427.32Vevorisertib
CAS:<p>Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor with inhibitory effects on AKT1/AKT2/AKT3.</p>Formula:C35H38N8OPurity:98.88%Color and Shape:SolidMolecular weight:586.73SC79
CAS:<p>SC79 is an AKT agonist with specificity and blood-brain barrier permeability.</p>Formula:C17H17ClN2O5Purity:98% - >99.99%Color and Shape:SolidMolecular weight:364.78FRAX1036
CAS:<p>FRAX-1036 is a effective and selective PAK1 inhibitor.</p>Formula:C28H32ClN7OPurity:97.66% - 98.67%Color and Shape:SolidMolecular weight:518.05Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formula:C14H11N3O3SPurity:98% - 99.91%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:301.32G-5555 hydrochloride
<p>G-5555 hydrochloride is a potent and selective inhibitor of PAK1 (Ki: 3.7 nM).</p>Formula:C25H26Cl2N6O3Color and Shape:SolidMolecular weight:529.42CEP-37440
CAS:<p>CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).</p>Formula:C30H38ClN7O3Purity:98.86% - 99.98%Color and Shape:SolidMolecular weight:580.12Darovasertib
CAS:<p>Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).</p>Formula:C22H23F3N8OPurity:98.72% - ≥95%Color and Shape:SolidMolecular weight:472.47Go 6983
CAS:<p>Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!</p>Formula:C26H26N4O3Purity:98.41% - 99.85%Color and Shape:SolidMolecular weight:442.51Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34Asciminib
CAS:<p>Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).</p>Formula:C20H18ClF2N5O3Purity:98.82% - 99.70%Color and Shape:SolidMolecular weight:449.84Olverembatinib dimesylate
CAS:<p>Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).</p>Formula:C29H27F3N6O·2CH4O3SPurity:97.66% - >99.99%Color and Shape:SolidMolecular weight:724.77FRAX597
CAS:<p>FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).</p>Formula:C29H28ClN7OSPurity:97.34% - 99.85%Color and Shape:SolidMolecular weight:558.1GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Formula:C20H35N7O7Purity:>99.99%Color and Shape:SolidMolecular weight:485.53PF-04929113 Mesylate
CAS:<p>PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37</p>Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63PF-562271 besylate
CAS:<p>PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.</p>Formula:C21H20F3N7O3S·C6H6O3SPurity:97.65% - 99.01%Color and Shape:SolidMolecular weight:665.66Danegaptide Hydrochloride
CAS:<p>Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.</p>Formula:C14H18ClN3O4Purity:99.55%Color and Shape:SolidMolecular weight:327.76Chelerythrine
CAS:<p>1.</p>Formula:C21H18NO4Purity:98.36%Color and Shape:SolidMolecular weight:348.37Bafetinib
CAS:<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62BGG463
CAS:<p>BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.</p>Formula:C30H29F3N6O3Purity:95.05% - >99.99%Color and Shape:SolidMolecular weight:578.58Miransertib
CAS:<p>Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.</p>Formula:C27H24N6Purity:99.85% - ≥95%Color and Shape:SolidMolecular weight:432.52GNF-5
CAS:<p>GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.</p>Formula:C20H17F3N4O3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:418.37Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36DDO-5936
CAS:<p>DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.</p>Formula:C25H29N5O4SPurity:99.81%Color and Shape:SolidMolecular weight:495.59Taurochenodeoxycholic Acid
CAS:<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Formula:C26H45NO6SPurity:99.53% - 99.86%Color and Shape:SolidMolecular weight:499.7ATM-3507 trihydrochloride
CAS:<p>ATM-3507 trihydrochloride, a potent inhibitor of tropomyosin, demonstrates inhibition concentration (IC50) values ranging from 3.83 to 6.84 μM across various</p>Formula:C37H49Cl3FN5O2Color and Shape:SolidMolecular weight:721.17AG957
CAS:<p>Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in</p>Formula:C15H15NO4Purity:98.82%Color and Shape:SolidMolecular weight:273.28p5 Ligand for Dnak and DnaJ acetate
<p>p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).</p>Formula:C46H85N15O13SPurity:96.33%Color and Shape:SolidMolecular weight:1088.32Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Formula:C26H32ClN7O4SColor and Shape:SolidMolecular weight:574.09Daphnoretin
CAS:<p>1.</p>Formula:C19H12O7Purity:98% - 99.85%Color and Shape:SolidMolecular weight:352.29Cyclo(-RGDfK)
CAS:<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Formula:C27H41N9O7Purity:95.29% - >99.99%Color and Shape:SolidMolecular weight:603.67
