Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1382 products of "Cytoskeletal Signaling"
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Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Formula:C20H23N5OColor and Shape:SolidMolecular weight:349.43Mps1-IN-4
CAS:<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Formula:C26H31F3N6O2Color and Shape:SolidMolecular weight:516.56AP 24149
CAS:<p>AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.</p>Formula:C23H24N5OPColor and Shape:SolidMolecular weight:417.44SB26019
CAS:<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Formula:C24H20O4Color and Shape:SolidMolecular weight:372.41YW1159
CAS:<p>YW1159 is an inhibitor of Wnt signaling.</p>Formula:C19H14FN5OColor and Shape:SolidMolecular weight:347.35AMXI-5001
CAS:<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Formula:C25H20FN5O3Color and Shape:SolidMolecular weight:457.46Tubulin polymerization-IN-21
CAS:<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Formula:C30H29NO7Color and Shape:SolidMolecular weight:515.55AM-9635
CAS:<p>AM-9635: Potent PI3Kδ inhibitor, cellular IC50 4.2 nM, reduces IgG/IgM, well-tolerated, affects cell growth/division.</p>Formula:C19H14F2N8Color and Shape:SolidMolecular weight:392.36Clathrin-IN-2
CAS:<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Formula:C17H18Br2N2OColor and Shape:SolidMolecular weight:426.15Tubulin inhibitor 20
CAS:<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34BIIB028
CAS:<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Formula:C19H21ClN5O5PColor and Shape:SolidMolecular weight:465.83Tubulin inhibitor 26
CAS:<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Formula:C17H19N3O3Color and Shape:SolidMolecular weight:313.35O-GlcNAcase-IN-4
CAS:<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Formula:C16H22FN5O3SColor and Shape:SolidMolecular weight:383.44BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formula:C26H20Cl2N4O4SColor and Shape:SolidMolecular weight:555.43Tubulin polymerization-IN-37
CAS:<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formula:C25H29N3NaO7SColor and Shape:SolidMolecular weight:538.57THK-5117
CAS:<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formula:C13H14N2O4Purity:99.61%Color and Shape:SolidMolecular weight:262.26XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formula:C25H21Cl2N3O8Color and Shape:SolidMolecular weight:562.36Debio 0617B
CAS:<p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>Formula:C28H23ClF3N7O2Color and Shape:SolidMolecular weight:581.98Antitumor agent-68
CAS:<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Formula:C17H11NO2Color and Shape:SolidMolecular weight:261.27Antitumor agent-71
CAS:<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Formula:C26H31N5O4SColor and Shape:SolidMolecular weight:509.62BMS-358233
CAS:<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Formula:C25H25ClN6O2SColor and Shape:SolidMolecular weight:509.02PU24FCl
CAS:<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Formula:C20H21ClFN5O3Color and Shape:SolidMolecular weight:433.86KIF18A-IN-4
CAS:<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Formula:C22H27N3O3SColor and Shape:SolidMolecular weight:413.53Sabeluzole
CAS:<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Formula:C22H26FN3O2SPurity:98.51%Color and Shape:SolidMolecular weight:415.52Valategrast hydrochloride
CAS:<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formula:C28H35F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:672.67K-80003
CAS:<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Formula:C22H21FO2Purity:99.76%Color and Shape:SolidMolecular weight:336.4PS315
CAS:<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Formula:C23H19ClO2Purity:98%Color and Shape:SolidMolecular weight:362.85AKT-IN-2
CAS:<p>AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).</p>Formula:C25H34F3N7OPurity:98%Color and Shape:SolidMolecular weight:505.58Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formula:C30H32ClN7OSPurity:98%Color and Shape:SolidMolecular weight:574.14GB1874
CAS:<p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>Formula:C24H27N3O2SColor and Shape:SolidMolecular weight:421.56AMP-PCP
CAS:<p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>Formula:C11H18N5O12P3Purity:98%Color and Shape:SolidMolecular weight:505.21SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Formula:C15H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:319.81Eg5 Inhibitor V, trans-24
CAS:<p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>Formula:C26H21N3O3Purity:99.75%Color and Shape:SolidMolecular weight:423.46BBO-10203
CAS:<p>BBO-10203 is an oral small molecule that disrupts PI3Kα-Ras interaction, inhibits Akt signaling selectively, and targets KRAS-mutant tumors.</p>Formula:C34H30F2N6O3SPurity:98.62%Color and Shape:SolidMolecular weight:640.7ZINC194100678
CAS:<p>ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.</p>Formula:C10H13N5OPurity:98.3%Color and Shape:SolidMolecular weight:219.24TC-Mps1-12
CAS:<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Formula:C17H20N6OPurity:98%Color and Shape:SolidMolecular weight:324.38KP-23172
CAS:<p>KP-23172 is a inhibitor of PI3-K/Akt pathway.</p>Formula:C10H4N6OPurity:98%Color and Shape:SolidMolecular weight:224.18Tau-aggregation and neuroinflammation-IN-1
CAS:<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Formula:C25H20N2O7Purity:99.85%Color and Shape:SolidMolecular weight:460.44BCR-ABL-IN-7
CAS:<p>BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.</p>Formula:C19H16FN3O3SPurity:98.28%Color and Shape:SolidMolecular weight:385.41CpCDPK1/TgCDPK1-IN-1
CAS:<p>CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.</p>Formula:C18H17N5Purity:99.61%Color and Shape:SolidMolecular weight:303.36AM-5308
CAS:<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Formula:C26H35N5O5SPurity:98.06% - 99.58%Color and Shape:SolidMolecular weight:529.65CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formula:C18H18ClN5OPurity:98.81%Color and Shape:SolidMolecular weight:355.82Pentachloropseudilin
CAS:<p>Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.</p>Formula:C10H4Cl5NOPurity:98.14%Color and Shape:SolidMolecular weight:331.41Tyrphostin AG 568
CAS:<p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>Formula:C13H9N5O2Purity:98%Color and Shape:SolidMolecular weight:267.24DHNQ
CAS:<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Formula:C18H14N2OColor and Shape:SolidMolecular weight:274.32NSC305787
CAS:<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Formula:C25H30Cl2N2OPurity:99.40%Color and Shape:SolidMolecular weight:445.42Clathrin-IN-25
CAS:<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Formula:C19H13KNO5SColor and Shape:SolidMolecular weight:406.47
