Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1381 products of "Cytoskeletal Signaling"
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Microtubule inhibitor 1
CAS:<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Formula:C21H19NO3Purity:98%Color and Shape:SolidMolecular weight:333.38KY-04031
CAS:<p>KY-04031 is an inhibitor of p21-activated kinase 4.</p>Formula:C21H20N8OColor and Shape:SolidMolecular weight:400.44AFG210
CAS:<p>AFG210 is a novel first-generation “type II” FLT3 inhibitor.</p>Formula:C19H14F3N3O2Color and Shape:SolidMolecular weight:373.33Antitumor agent-68
CAS:<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Formula:C17H11NO2Color and Shape:SolidMolecular weight:261.27Tubulin inhibitor 28
CAS:<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Formula:C12H8Br2S2Color and Shape:SolidMolecular weight:376.13BCR-ABL-IN-5
CAS:<p>BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.</p>Formula:C25H21Cl2N5O2Color and Shape:SolidMolecular weight:494.37cemadotin free base
CAS:<p>Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks</p>Formula:C35H56N6O5Purity:98.70% - 99.64%Color and Shape:SolidMolecular weight:640.86Tubulin polymerization-IN-10
CAS:<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43Iso-Fludelone
CAS:<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Formula:C27H36F3NO6Color and Shape:SolidMolecular weight:527.5710-DEBC hydrochloride
CAS:<p>10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].</p>Formula:C20H26Cl2N2OColor and Shape:SolidMolecular weight:381.34DRP1i27
CAS:<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Formula:C20H26N6OColor and Shape:SolidMolecular weight:366.46KY-04045
CAS:<p>KY-04045 is a PAK4 inhibitor.</p>Formula:C13H14BrN5Color and Shape:SolidMolecular weight:320.19HSP90-IN-22
CAS:<p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>Formula:C25H30N4O3Purity:98%Color and Shape:SolidMolecular weight:434.53SSTC3
CAS:<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Formula:C23H17F3N4O3S2Purity:98.65% - 99.94%Color and Shape:SolidMolecular weight:518.53IQTub4P
CAS:<p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>Formula:C19H18NNa2O8PColor and Shape:SolidMolecular weight:465.305CHMFL-ABL-053
CAS:<p>CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.</p>Formula:C28H26F3N7O2Color and Shape:SolidMolecular weight:549.55BuChE-IN-5
CAS:<p>"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."</p>Formula:C25H35N3Color and Shape:SolidMolecular weight:377.57CHPG sodium salt
CAS:<p>CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways.</p>Formula:C8H7ClNNaO3Purity:>99.99%Color and Shape:SolidMolecular weight:223.59Tubulin inhibitor 27
CAS:<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Formula:C21H19NO4Color and Shape:SolidMolecular weight:349.38AJH-836
CAS:<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Formula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53ARUK3001185
CAS:<p>ARUK3001185 (8l): potent, selective Notum inhibitor; oral, brain-penetrant; IC50=6.7 nM; for rodent disease models.</p>Formula:C9H4Cl2F3N3Color and Shape:SolidMolecular weight:282.05Microtubule inhibitor 5
CAS:<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Formula:C22H15FN2O4Color and Shape:SolidMolecular weight:390.36AM-9635
CAS:<p>AM-9635: Potent PI3Kδ inhibitor, cellular IC50 4.2 nM, reduces IgG/IgM, well-tolerated, affects cell growth/division.</p>Formula:C19H14F2N8Color and Shape:SolidMolecular weight:392.36Pentachloropseudilin
CAS:<p>Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.</p>Formula:C10H4Cl5NOPurity:98.14%Color and Shape:SolidMolecular weight:331.41Debio 0617B
CAS:<p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>Formula:C28H23ClF3N7O2Color and Shape:SolidMolecular weight:581.98Tubulin polymerization-IN-21
CAS:<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Formula:C30H29NO7Color and Shape:SolidMolecular weight:515.55Bimoclomol
CAS:<p>Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.</p>Formula:C14H20ClN3O2Color and Shape:SolidMolecular weight:297.78Cardionogen 1
CAS:<p>Wnt signaling modulator</p>Formula:C13H14N4OSPurity:98%Color and Shape:SolidMolecular weight:274.34Creatine monohydrate
CAS:<p>Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.</p>Formula:C4H11N3O3Purity:99.87%Color and Shape:White SolidMolecular weight:149.15Amphethinile
CAS:<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Formula:C15H11N3SPurity:98%Color and Shape:SolidMolecular weight:265.33Microtubule inhibitor 4
CAS:<p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>Formula:C25H23FN4O3Color and Shape:SolidMolecular weight:446.47BIIB028
CAS:<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Formula:C19H21ClN5O5PColor and Shape:SolidMolecular weight:465.83Microtubule inhibitor 3
CAS:<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Formula:C26H23FN4O3Color and Shape:SolidMolecular weight:458.48UR-3216
CAS:<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Formula:C27H29N7O7Purity:98%Color and Shape:SolidMolecular weight:563.56KUNB31
CAS:<p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>Formula:C19H18N2O3Color and Shape:SolidMolecular weight:322.36Synstab A
CAS:<p>Synstab A is a microtubule stabilizer.</p>Formula:C15H13BrCl3N3O3SColor and Shape:SolidMolecular weight:501.61HSP90-IN-14
CAS:<p>HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.</p>Formula:C14H8Cl2N4O4SColor and Shape:SolidMolecular weight:399.21GNF-1331
CAS:<p>GNF-1331: potent, selective oral porcupine inhibitor; IC50=12 nM; targets aberrant Wnt signaling in cancers.</p>Formula:C20H20N6O2S2Color and Shape:SolidMolecular weight:440.54Tau protein aggregation-IN-1
CAS:<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Formula:C17H11BrN2O2Color and Shape:SolidMolecular weight:355.19Tubulozole
CAS:<p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>Formula:C23H23Cl2N3O4SPurity:98%Color and Shape:SolidMolecular weight:508.42CK2-IN-9
CAS:<p>CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter</p>Formula:C23H29N9OColor and Shape:SolidMolecular weight:447.54Tubulin inhibitor 20
CAS:<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34S516
CAS:<p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>Formula:C21H19N5O4SPurity:98%Color and Shape:SolidMolecular weight:437.47FAK inhibitor 2
CAS:<p>FAK inhibitor 2, antitumor and anti-angiogenesis activitiesis ,is a potent focal adhesion kinase (FAK) inhibitor with an IC50 of 0.07 nM .</p>Formula:C29H33F3N8O2S2Color and Shape:SolidMolecular weight:646.75BMS-688521
CAS:<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37M435-1279
CAS:<p>M435-1279 is a UBE2T inhibitor. M435-1279 blocks UBE2T-mediated degradation of RACK1, leading to inhibit the hyperactivation of Wnt/β-catenin signaling pathway.</p>Formula:C18H17N3O5S2Purity:97.16%Color and Shape:SolidMolecular weight:419.47QS11
CAS:<p>QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.</p>Formula:C36H33N5O2Purity:98.59%Color and Shape:SolidMolecular weight:567.68Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formula:C30H32Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:604.95Tubulin polymerization-IN-18
CAS:<p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>Formula:C25H25NO6Color and Shape:SolidMolecular weight:435.47β-catenin-IN-3
CAS:<p>β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces the</p>Formula:C19H20Br2N2OSColor and Shape:SolidMolecular weight:484.25
