Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
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NVS-PAK1-1
CAS:1783816-74-9
NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).
Formula:
C23H25ClF3N5O
Purity:
99.35%
Color and Shape:
Solid
Molecular weight:
479.93
Ref: TM-T16367
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 362.00 € | ||
| 50mg | 541.00 € | ||
| 100mg | 769.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BNC105
CAS:945771-74-4
BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
Formula:
C20H20O7
Purity:
96.57%
Color and Shape:
Solid
Molecular weight:
372.37
Ref: TM-T14694
| 1mg | 81.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 910.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Danicamtiv
CAS:1970972-74-7
Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of …
Formula:
C16H20F3N5O4S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
435.42
Ref: TM-T15050
| 1mg | 134.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 449.00 € | ||
| 25mg | 740.00 € | ||
| 50mg | 1,013.00 € | ||
| 100mg | 1,388.00 € | ||
| 1mL*10mM (DMSO) | 299.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Col003
CAS:328565-16-8
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding …
Formula:
C14H11NO4
Purity:
98.67% - 99.03%
Color and Shape:
Solid
Molecular weight:
257.24
Ref: TM-T10860
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 531.00 € | ||
| 200mg | 761.00 € | ||
| 500mg | 1,143.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
ALK inhibitor 1
CAS:761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
Formula:
C23H28BrN7O3S
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
562.48
Ref: TM-T10285
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 621.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Entasobulin
CAS:501921-61-5
Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
Formula:
C26H18ClN3O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
439.89
Ref: TM-T15236
| 5mg | 44.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 250.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Bisindolylmaleimide VIII acetate
CAS:138516-31-1
Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in …
Formula:
C26H26N4O4
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
458.51
Ref: TM-T10549
| 1mg | 46.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 592.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Tubulin inhibitor 6
CAS:105925-39-1
Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple …
Formula:
C20H14ClNO2S
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
367.85
Ref: TM-T13224
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 249.00 € | ||
| 200mg | 355.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.
Formula:
C17H31N7O10
Purity:
98.14%
Color and Shape:
Solid
Molecular weight:
493.47
Ref: TM-T10366L
| 5mg | 41.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 155.00 € | ||
| 100mg | 271.00 € | ||
| 200mg | 407.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Arimoclomol maleate
CAS:289893-26-1
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
Formula:
C18H24ClN3O7
Purity:
99.9% - 99.98%
Color and Shape:
Solid
Molecular weight:
429.85
Ref: TM-T13554
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 230.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Rifabutin
CAS:72559-06-9
Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.
Formula:
C46H62N4O11
Purity:
99.27% - 99.8%
Color and Shape:
Red-Violet Crystalline Powder
Molecular weight:
847
Ref: TM-T1501
| 25mg | 49.00 € | ||
| 50mg | 60.00 € | ||
| 100mg | 85.00 € | ||
| 200mg | 136.00 € | ||
| 500mg | 222.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Nilotinib
CAS:641571-10-0
Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be …
Formula:
C28H22F3N7O
Purity:
99.61% - 99.83%
Color and Shape:
Off-White Solid
Molecular weight:
529.52
Ref: TM-T1524
| 50mg | 46.00 € | ||
| 100mg | 54.00 € | ||
| 200mg | 59.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Crolibulin
CAS:1000852-17-4
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
Formula:
C18H17BrN4O3
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
417.26
Ref: TM-T15012
| 1mg | 63.00 € | ||
| 2mg | 92.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 214.00 € | ||
| 25mg | 372.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 748.00 € | ||
| 1mL*10mM (DMSO) | 149.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Recilisib
CAS:334969-03-8
Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.
Formula:
C16H13ClO4S
Purity:
98.85% - 99.84%
Color and Shape:
Solid
Molecular weight:
336.79
Ref: TM-T13862
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 520.00 € | ||
| 500mg | 1,140.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
RWJ 50271
CAS:162112-37-0
RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.
Formula:
C18H17F3N4O2S
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
410.41
Ref: TM-T12783
| 1mg | 156.00 € | ||
| 5mg | 372.00 € | ||
| 10mg | 557.00 € | ||
| 25mg | 875.00 € | ||
| 50mg | 1,167.00 € | ||
| 100mg | 1,584.00 € | ||
| 1mL*10mM (DMSO) | 421.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Dasatinib monohydrate
CAS:863127-77-9
Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.
Formula:
C22H28ClN7O3S
Purity:
100% - 99.89%
Color and Shape:
Solid
Molecular weight:
506.03
Ref: TM-T1448L
| 50mg | 44.00 € | ||
| 100mg | 59.00 € | ||
| 200mg | 77.00 € | ||
| 500mg | 103.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
ATN-161 trifluoroacetate salt
CAS:904763-27-5
ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival …
Formula:
C25H36F3N9O10S
Purity:
98% - 99.98%
Color and Shape:
Solid
Molecular weight:
711.67
Ref: TM-T10397
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 548.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Paprotrain
CAS:57046-73-8
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and …
Formula:
C16H11N3
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
245.28
Ref: TM-T12359
| 5mg | 48.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 250.00 € | ||
| 200mg | 373.00 € | ||
| 500mg | 609.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Imatinib Mesylate
CAS:220127-57-1
Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, …
Formula:
C29H31N7O·CH4SO3
Purity:
100% - 98.92%
Color and Shape:
White Crystalline Powder
Molecular weight:
589.71
Ref: TM-T1621
| 1u | 163.20 € | ||
| 200mg | 59.00 € | ||
| 500mg | 89.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CMPD101
CAS:865608-11-3
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).
Formula:
C24H21F3N6O
Purity:
98.34% - 99.01%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T14989
| 1mg | 65.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 582.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
