Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1460 products of "Cytoskeletal Signaling"
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Vindesine sulfate
CAS:Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.Formula:C43H57N5O11SPurity:97.51%Color and Shape:Amorphous SolidMolecular weight:852Asciminib
CAS:<p>Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).</p>Formula:C20H18ClF2N5O3Purity:98.82% - 99.70%Color and Shape:SolidMolecular weight:449.84MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formula:C22H34O2Purity:97.024%Color and Shape:SolidMolecular weight:330.5GNF-2
CAS:<p>GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.</p>Formula:C18H13F3N4O2Purity:98.17% - ≥95%Color and Shape:SolidMolecular weight:374.32AT7867
CAS:<p>AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.</p>Formula:C20H20ClN3Purity:99.63%Color and Shape:SolidMolecular weight:337.85VER-49009
CAS:<p>VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).</p>Formula:C19H18ClN3O4Purity:99.36% - 99.99%Color and Shape:SolidMolecular weight:387.82Tianeptine
CAS:Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。Formula:C21H25ClN2O4SPurity:99.04%Color and Shape:SolidMolecular weight:436.95PRE-084 hydrochloride
CAS:<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Formula:C19H28ClNO3Purity:99.54%Color and Shape:SolidMolecular weight:353.88Capivasertib
CAS:<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Formula:C21H25ClN6O2Purity:97.59% - 99.6%Color and Shape:SolidMolecular weight:428.92Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formula:C24H31N3O3Purity:99.01% - 99.66%Color and Shape:SolidMolecular weight:409.52MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purity:98.53%Color and Shape:Yellow PowderMolecular weight:193.16AKT-IN-1
CAS:<p>AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).</p>Formula:C22H21N3OPurity:98.63%Color and Shape:SolidMolecular weight:343.42Recilisib sodium
CAS:Recilisib (ON 01210.Na) is a radioprotective agent altering cancer cell cycles and preventing radiation-induced apoptosis.Formula:C16H13ClNaO4SColor and Shape:SolidMolecular weight:359.78TR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33Arg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36NSC45586
CAS:<p>NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.</p>Formula:C20H18N6NaO3Purity:99.31%Color and Shape:SolidMolecular weight:413.4Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Formula:C18H14N2O4Purity:95.85% - 99.22%Color and Shape:SolidMolecular weight:322.31Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formula:C31H43F6N9O12Purity:95.28% - ≥95%Color and Shape:SolidMolecular weight:847.722-hydroxy Flutamide
CAS:<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Formula:C11H11F3N2O4Purity:99.45% - 99.82%Color and Shape:SolidMolecular weight:292.21
