Deuterated Compounds

Applications Used in the preparation of piperazine-1-carboxamide derivatives as fatty acid amide hydrolase (FAAH) inhibitors.
References Glorius, F., et al.: Org. Biomol. Chem., 3, 4171 (2005),

Applications Rosiglitazone (Rosiglitazone (R693500) Rosiglitazone (R693500) ) derivative.Thiazolidinedione derivative, with antidiabetic properties.

Applications Isotope labelled 4-Bromo-α-phenylbenzenemethanol is used in the synthesis of diarylmethylpiperazines as potent and selective nonpeptidic δ-opioid receptor agonists. Is used in the ysnthesis of bronsted acid-catalyzed benzylation of 1,3-dicarbonyl derivatives.
References Plobeck, N. et al.: J. Med. Chem., 43, 3878 (2000); Sanz, R. et al.: Org. Lett., 9, 2027 (2007);

Applications N-tert-Boc-2-(4-hydroxy-2-methoxyphenoxy)ethylamine-d3 (cas# 1189659-07-1) is a compound useful in organic synthesis.

Applications 2-(2-Aminothiazol-4-yl)acetic Acid-13C, 15N2 Hydrochloride is an intermediate used in the synthesis of Cefotiam Dihydrochloride-13C, 15N2 (C243007), which is labelled Cefotiam Dihydrochloride (C243005), which is an antibiotic product used in injections to treat bacterial infections. Cefotiam Dihydrochloride can also reduce allergic reactions and mixed with pharmaceutical carriers for medical formulations.
References Jiang, C., et al.: Faming Zhuanli Shenqing, CN 105646539 A, 20160608 (2016); Liu, X.: Faming Zhuanli Shenqing, CN 105193819 A, 20151230, (2015); Weng, Y., et al.: Faming Zhuanli Shenqing, CN 103601737 A. 20140226 (2014)

Applications 3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-propanol-d6 is a compound useful in organic synthesis.

Applications Toluene-2-d1 (CAS# 4409-84-1) is a useful isotopically labeled research compound. This compound can be used in preparation for various organic synthesis applications, and for determining deuterium isotopic effects in 13C NMR spectra of benzene derivatives.
References Zaidlewicz, M.,et.al., Sci. Synth, 6,921-943,(2004); Novak, P.,et.al., Magn.Reson.Chem., 34,610-615,(1996);

Applications Toluene-3-d1 (CAS# 4409-85-2) is a useful isotopically labeled research compound. This compound can be used for spectroscopic studies on toluene and deuterated derivatives.
References Balfour, W., et.al., Can. J. Phys., 72, 1225-1235,(1994);

Applications Cyclohexanol-d11 is the deuterated analog of cyclohexane, general organic chemical solvent. It is also used as a precursor to the synthesis of nylon.
References Hiroshi O. et al.: J. Memb. Sci., 105, 51 (1995); Rekharsky, M.V. et al.: J. Am. Chem. Soc., 124, 12361 (2002)

Applications Monomethyl Glutarate-1,5-13C2 (cas# 1189708-76-6) is a compound useful in organic synthesis.

Applications Methyl Valerimidate-d9 Hydrochloride (cas# 1030939-72-0) is a compound useful in organic synthesis.

Applications A labelled intermediate in the preparation of DOPA-decarboxylase inhibitors.

Applications 1-Bromobenzene-13C6 is the isotope labelled analog of 1-Bromobenzene, which is used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);

Applications 1-(tert-Butyldimethylsilyloxy)-1-ethynyl-cyclopropane-d4 (cas# 1246817-59-3) is a compound useful in organic synthesis.

Applications rac 10-Hydroxy-1-undecen-6-one-d6 (cas# 1246818-57-4) is a compound useful in organic synthesis.

Applications Intermediate for the preparation of Isotope Labelled Tolmetin.

Applications 2-(Cyclopropylmethoxy-d4)-acetic Acid (cas# 1346602-05-8) is a compound useful in organic synthesis.

Applications 2-​(Methoxy-​d3)​-​3-​(1-​methylethyl)​pyrazine is a useful compound in the study of isotope effect in gas liquid chromatography separation of deuterated and nondeuterated compounds using ionic liquid stationary phases.
References Schmarr, H., et al.: J. Chromatogr. A., 1270, 310 (2012);

Applications 4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile-d8 is an intermediate from the synthesis of Etravirine-d8 (E937003). Etravirine-d8 is a novel labelled HIV reverse transcriptase inhibitor useful in treatment of HIV infection.
References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008); Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008)

Applications p-Vinylguaiacol-d3 is the isotope labelled analog of p-Vinylguaiacol (V424960); an aromatic substance, one of the compounds responsible for the natural aroma of buckwheat, and also one of the major pyrolytic products of (E)-N-[(4-hydroxy-3-methoxy)-phenethyl]-3-[(3-methoxy-4-O-β-D-glucopyranosyloxy) phenyl] acrylamide; a new gycloside in tobacco.
References Janes, Damjan., et al.: Food Chem., 112(1), 120-124 (2009); Zhou, Rong., et al.: Yancao Keji, (7), 34-36, 42 (2013)

Applications N-(1,1-Dimethylethyl)-benzenemethanamine-d9 Hydrobromide (cas# 1346605-21-7) is a compound useful in organic synthesis.

Applications Balsalazide-d3 Disodium Salt is a labeled analogue of Sulfasalazine (S699084). A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).
References Prakash, A., et al.: Drugs, 56, 83 (1998); Coyne, C., et al.: Mol. Biol. Cell, 13, 3218 (2002); Willemsen, L., et al.: Clin. Exp. Immunol., 142, 275 (2005)

Applications A deuterated intermediate in the synthesis of Carisoprodol.

Applications O-Benzyl-S-(methyl-d3)-3-thioacetaminophen is a useful synthetic intermediate for organic reactions.

Applications (R)-2-Hydroxy-3-(benzoyloxy)propyl-1,1-d2 4-Toluenesulfonate is an intermediate used in the synthesis of (S)-PA 824-d4 (P122502), which is a labelled novel anti-tuberculosis drug.
References Diacon, A.H. et al.: Antimicrob. Anents Chemother., 54, 3402 (2010); Dogra, M. et al.: Br. J. Pharmacol., 162, 226 (2010); Ginsberg, A.M. et al.: Antimicrob. Agents Chemother., 53, 3720 (2009);

Applications 1,2,3,5-Tetrachlorobenzene-d2 (CAS# 2199-74-8) is a useful isotopically labeled research compound.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-Chloro-2-methoxy-benzoic Acid-13C,d3 (cas# 1346600-36-9) is a compound useful in organic synthesis.

Applications N-[2-[5-(Acetyloxy)-1H-indol-3-yl]ethyl]acetamide-D6 is an intermediate used in the synthesis of N-Acetyl-d3-5-hydroxytryptamine (A179162), which is deuterium labelled N-Acetyl-5-hydroxytryptamine (A179160), which is a metabolite of Melatonin (M215000).
References Reiter, R.J., et al.: J. Biomed. Sci., 7, 444 (2000), Chen, Z., et al.: Am. J. Physiol, 284, 1618 (2003), Barrenetxe, J., et al.: J. Physiol. Biochem., 60, 61 (2004),

Applications N,N'-Dimethyl-3,3'-dithiodipropionamide is an disulfide linked compound found in antifouling coatings and is also an intermediate in the synthesis of antimicrobial agents and biocides.
References Easton, C.J., et al.: J. Chem. Soc., 1, 153 (1985);

Applications 2,5-Dihydro-2-hydroxy-5-nitro-2-furanmethanediol-d3 Triacetate (cas# 1346604-22-5) is a compound useful in organic synthesis.

Applications Imidazol-1-yl-acetic Acid-15N2,13C2 (cas# 1184983-00-3) is a compound useful in organic synthesis.

Applications Fluorene-D10 is a labelled analogue of Fluorene (F462000). Fluorene is a polycyclic aromatic hydrocarbon that is ubiquitous in the urban environment, and is also a suspected carcinogen. Fluorene is used as a component of fluorescent probes that bind to human serum albumin, allowing researchers to study internal mechanisms more closely.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harrison, R., et al.: Env. Sci. Tech., 30, 825 (1996); Park, K., et al.: Org. Biomol. Chem., 7, 4225 (2009); Weissenfels, W., et al.: Appl. Micro. Biotech., 32, 479 (1990)

Applications Ethyl (5-Ethyl-2-pyridinyl)-1,1-d2-acetate (cas# 1189654-25-8) is a compound useful in organic synthesis.

Applications 1,2-Dimethoxybenzene-3,4,5,6-d4 (CAS# 126840-15-1) is a useful isotopically labeled research compound.

Applications Wittig reagent

Applications Isotope labelled analogue of tert-Pentyl Chloride, an alkyl chloride used as a starting material in various organic synthesis.

Applications A labelled intermediate in the syntheis of a metabolite of the anti-cancer drug Tamoxifen.

Applications 2-(Formylamino)-3-hydroxy-2-propenoic-13C2 Acid Ethyl Ester (cas# 1391062-48-8) is a compound useful in organic synthesis.

Applications α-Methyl-2-piperidinemethanol-13C2 is a labelled analogue of α-Methyl-2-piperidinemethanol (M324830), which can be used in the preparation of substances with herbicidal activity. α-Methyl-2-piperidinemethanol-13C2 is also an intermediate in synthesizing 2-Acetyl-3,4,5,6-tetrahydropyridine-13C2 Hydrochloride (A188502), which is a labelled 2-Acetyl-3,4,5,6-tetrahydropyridine (A188500), the most important bread flavor component.
References Buttery, R.G., et al.: J. Agric. Food Chem., 43, 1878 (1995)

Applications Methyl-(4-nitrophenylethyl)-4-(nitrophenoxyethyl)amine-d4 (cas# 1189869-42-8) is a compound useful in organic synthesis.

Applications 2,2-Difluoroethylamine-d2 Hydrochloride is an intermediate used in the synthesis of Flupyradifurone-d5 (F598616), which is the labeled form of Flupyradifurone (F598615), can be used as an insecticide.
References Anon, IP.com J., 12, 19 (2011)

Applications (4E)-Octenedinitrile-1,8-13C2 (cas# 1185245-34-4) is a compound useful in organic synthesis.

Applications Dimethyl-d6-(tetrahydro-3,3-diphenyl-2-furylidene)ammonium Bromide is a compound useful in organic synthesis.

Applications 4-Chloro-N-[2-(4-hydroxyphenyl)ethyl]benzamide-d4 (cas# 1189464-84-3) is a compound useful in organic synthesis.

Applications 2-(Benzoyloxy)ethyl-d4 Benzoate is an intermediate in the synthesis of Acyclovir-d4 (A192402), an orally active acyclic labelled nucleoside with inhibitory activity towards several herpes viruses. Antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)

Applications Labelled Nitisinone intermediate.

Applications Tributyl(vinyl)tin-d3 is an intermediate for the synthesis of Protoporphyrin IX Dimethyl Ester-d6 (P839127), which is the labelled version of Protoporphyrin IX P(P838900). Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme and PPIX-based strategies have been used for cancer diagnosis and treatment. It can be used in biological study for role of protoporphyrin IX in skin photosensitivity, biliary stones, hepatobiliary damage, liver failure and cancer diagnosis and treatment in human.
References Sachar, M., et al.: J. Pharmacol. Exp. Ther., 356, 267-275 (2016)

Applications Wittig reagent

Applications 2,4,6-Trimethyl-5-nitrobenzene-d11 (cas# 1126138-12-2) is a compound useful in organic synthesis.

Applications 2-Cyano-acetic Acid Sodium Salt-13C2 (cas# 1346598-51-3) is a compound useful in organic synthesis.

Applications (Z)-2-(Methoxyimino)-3-oxobutanoic Acid-d3 Methyl Ester (cas# 1331636-65-7) is a compound useful in organic synthesis.

Applications Can be used in the preparation of substances for treatment of dermatological conditions and skin protection.

Applications 5,6-Diamino-2,4-dihydroxypyrimidine-13C2, Hydrochloride Salt (cas# 1346605-20-6) is a compound useful in organic synthesis.

Applications Benzyl 2,4-Dibromobutyrate-d5 i is a useful synthetic intermediate.

Applications Isotope labelled 2-Ethyl-1-hexanol is used in the preparation of succinate-based plasticizers for replacing phthalate plasticizers. Also used in the preparation of polymeric plasticizers.
References Stuart, A. et al.: Eur. Polym. J. 49, 2785 (2013); Braslau, R. et al.: J. Polym. Sci. Part. A. Polym. Chem., 51, 1175 (2013);

Applications 3-(4-Chlorophenyl)-1-isoindolinone-d4 is the isotope labelled analog of 3-(4-Chlorophenyl)-1-isoindolinone (C378535), which is an intermediate of Chlorthalidone (C427500), a diuretic and antihypertensive agent.
References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966), Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972), Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985),

Applications Cyanoacetic Acid-13C2 is an intermediate for the synthesis of Diclazuril-13C3,15N2 (D436202), which is the labelled analogue of Diclazuril (D436200). Diclazuril is a nucleotide analogue with broad-spectrum anticoccidial activity and a coccidiostat.
References Maes, L., et al.: J. Parasitol., 74, 931 (1988)

Applications Loratadine-d4 Epoxide N-Oxide (cas# 1794754-14-5) is a compound useful in organic synthesis.

Applications Diethyl Cromoglycate-D5 is an intermediate used in the synthesis of Cromolyn-d5 Disodium Salt (C815002), which is a chromone complex which blocks mast cell degranulation.
References Ashton, M.J., et al.: Toxicol. Appl. Pharmacol., 26, 319 (1973), Friday, G.A., et al.: Am. J. Ophthalmol., 95, 169 (1983)

Applications (3,3,4,4,4-d5)-(E/Z)-1-[4-(2-Chloroethoxy)phenyl]-1-[4-(t-butyldimethylsilyloxy)phenyl]-2-phenyl-1-butene (cas# 1020719-26-9) is a compound useful in organic synthesis.

Applications pro-pro-(s) Dihydrocuscohygrine and pro-pro-(r) Dihydrocuscohygrine mixture. Cuscohygrine (C845000) derivative. An alkaloid compound found in Convolvulus lanatus.
References El-Shazly, A. et al.: J. Bioscienc. 63, 321 (2008)

Applications N-(1-Naphthyl-d7-methyl)methylamine (cas# 1189686-07-4) is a compound useful in organic synthesis.

Applications Intermediate for the synthesis of Eprosartan-d3.

Applications 4-Amino-1-pentanol-d4 Hydrochloride Salt (cas# 1216414-18-4) is a compound useful in organic synthesis.

Applications An impurity found in tramadol (T712500).
References Medvedovici, A. et al.: J. Pharmac. Biomed. Anal., 34, 67 (2004);

Applications 4-Amino-1-pentanol-d4 is an intermediate in the synthesis of Hydroxychloroquine-d4 Sulfate (H916902), which is an antimalarial; antirheumatic; lupus erythematosus suppressant.
References Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),

Applications 3-Bromopyridine-d4 is the isotope labelled analog of 3-Bromopyridine (B686740). Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Colby, J., et al.: Biochem. J., 165, 395 (1977), Damani, L., et al.: Xenobiotica, 12, 527 (1982), Balzarini, J., et al.: J. Antimicrob. Chemother., 55, 135 (2005),

Applications 4-Amino-1-pentanol-d4 Benzyl Ether is an intermediate in the synthesis of Hydroxychloroquine-d4 Sulfate (H916902), which is an antimalarial; antirheumatic; lupus erythematosus suppressant.
References Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),

Applications Lapatinib-d7 Sulfoxide Dihydrochloride is a by-product during the synthesis of Lapatinib-d7 Dihydrochloride (L175807), a labeled Lapatinib (L175800), a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.
References Kim, T.E., et al.: Drugs, 6, 886 (2003); Wood, E.R., et al.: Cancer Res., 64, 6652 (2004); Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005)

Applications 2-(Benzyloxy)-1-propanol-d6 is an intermediate in the synthesis of Isotope labelled Propylene Glycol 2-Glucuronide which is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds.
References Szczepankiewicz, B. et al.: J. Med. Chem., 49, 3563 (2006); Mateus, R. et al.: Int. J. Pharm., 444, 106 (2013);

Applications 1-Propylamine-d3 is the isotope labelled analog of 1-Propylamine, which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. Also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Goto, T. et al.: Bioorg. Med. Chem., 21, 7025 (2013); Lee, C. et al.: Bioorg. Med. Chem. 21, 7125, (2013);

Applications Labelled Anisole. Anisole is used in perfumery.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Taylor, J.M., et al.: Toxicol. Appl. Pharmacol., 6, 378 (1964),

Applications 2-Butyl-d3-4-chloro-5-benzyloxymethyl-1H-imidazole (cas# 1189919-69-4) is a compound useful in organic synthesis.

Applications 5-Hydroxy-6-methyl-4-[[(4-methylphenyl)imino]methyl]-3-pyridinemethanol-d5 is an intermediate in the synthesis of labelled Pyridoxal phosphate.
References Sharif, S., et al.: J. Am. Chem. Soc., 129, 4440 (2007);

Applications 4-Dimethylaminobutyric Acid Hydrochloride-d6 is an intermediate in synthesizing 4-​(Dimethyloxidoamino)​butanoic Acid-d6 Hydrochloride (D447162), which is a labelled form of 4-​(Dimethyloxidoamino)​butanoic Acid (D447160). 4-​(Dimethyloxidoamino)​butanoic Acid is a metabolite of Lauramine Oxide (L178530), which is a frequently used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases. 4-Dimethylaminobutyric Acid Hydrochloride-d6 is also a labelled analogue of 4-Dimethylaminobutyric Acid Hydrochloride (D456545), which acts as a reagent for the design, synthesis and in the biological evaluation of novel water-soluble prodrug of Docetaxel with amino acid as linkers.
References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006); Turan, T.S., et al.: Xenobiotica, 11, 447 (1981); Ma, H., et al.: Chem. Biol. Drug Des. 88, 363 (2016);

Applications (R)-1-Tosyloxy-2,3-propanediol-d2 is an intermediate used in the synthesis of (S)-PA 824-d4 (P122502), which is a labelled novel anti-tuberculosis drug.
References Diacon, A.H. et al.: Antimicrob. Anents Chemother., 54, 3402 (2010); Dogra, M. et al.: Br. J. Pharmacol., 162, 226 (2010); Ginsberg, A.M. et al.: Antimicrob. Agents Chemother., 53, 3720 (2009);

Applications 2-Acetylbutanoic-d5 Acid Ethyl Ester (cas# 141327-44-8) is a compound useful in organic synthesis.

Applications D-Aspartic Acid-d3 L-Alanine Copper(II) Complex is an intermediate in the synthesis of D-Aspartic-2,3,3-d3 Acid (A790019) which is derived from D-Asparatic Acid (A790020), which is a non-essential amino acid found in food sources. Its conjugate base D-aspartate has potential use as an therapeutic agent in the treatment of schizophrenia-related symptoms.
References Errico, F. et al.: J. Neurosci., 28, 10404 (2008); Denu, J.M. et al.: Biochem., 34, 3396 (1995); Chen, P.E. et al.: Mol. Pharmacol., 67, 1470 (2005);

Applications Ethyl 4-Chlorobutyrate-d4 is an isotope labelled reagent used in the preparation of cyclopropane derivatives.
References Antipenko, L., et al.: Chem. Pharm. Bull., 57, 580 (2009), Kumar, A., et al.: Bioorg. Med. Chem., 17, 5285 (2009),

Applications Dimethyl-d6 Carbonate is the labeled analogue of Dimethyl Carbonate (D446705), which is used in the synthesis of phosphine-boranes in the preparation of new bidentate ligands. Also used in the synthesis of flavonoid analogs.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Imamoto, T. et al.: J. Am. Chem. Soc., 112, 5244 (1990); Cushman, M. et al.: J. Med. Chem., 34, 798 (1991)

Applications [4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methylsulfinyl)-5-pyrimidinyl]-ethyl Ester-d6 (cas# 1189487-47-5) is a compound useful in organic synthesis.

Applications Pyrimidine with the ability to form complexes with heavy metal ions.
References Iltzsch, M., et al.: Biochem. Pharmacol., 48, 781 (1994),

Applications Pyridine-N-oxide-d5 (cas# 19639-76-0) is a compound useful in organic synthesis.

Applications A labelled reactant used in the preparation of inhibitors for treatment of neurodegenerative diseases.

Applications 2-Bromoethyl-4-nitrophenyl Ether-d4 (cas# 1190017-10-7) is a compound useful in organic synthesis.

Applications 2-Amino-4,6-dihydroxypyrimidine-13C2 is an intermediate in the production of antimicrobial guanylsulfonamides.
References Barrett, O., et al.: ChemBioChem., 7, 1882 (2006), Patel, P., et al.: Bioorg. Med. Chem. Lett., 17, 6610 (2007), Gasser, L., et al.: Environ. Sci. Technol., 41, 2445 (2007)

Applications 5-Chloro-N-cyclohexylpentanamide-d11 (cas# 1073608-18-0) is a compound useful in organic synthesis.

Applications Intermediate in the production of labelled Lapatinib.
References Godeneche, D., et al.: Drug Metab. Disposition, 21, 93 (1993),

Applications Methyl nicotinate-2,4,5,6-d4 is a labelled form of methyl nicotinate (M323240), a useful synthetic intermediate, which can be used to prepare biarylcarboxamide inhibitors of phosphodiesterase IV and tumor necrosis factor-α in treatment of rheumatoid arthritis.
References Chambers, R., et al.: Bioorg. Med. Chem. Lett., 7, 739 (1997).

Applications An intermediate of Rosuvastatin (R700500).

Applications 2,3-Dichlorobenzamidyl Guanidine-13C2 (cas# 1185047-08-8) is a compound useful in organic synthesis.

Applications 1,1,2-Trimethyl-3-(4-sulfobutyl)benz[e]indolium-d6 Inner Salt is a labelled analogue of 1,1,2-Trimethyl-3-(4-sulfobutyl)benz[e]indolium Inner Salt (T796740). It is a reactant used in the preparation of liposomally formulated indocyanine green (LP-ICG) derivatives for near infrared fluorescence imaging of lymph nodes.
References Toyota, T., et. al.: Bioorg. Med. Chem., 22, 721 (2014)