Deuterated Compounds

Applications Sulfoxaflor-d3 is the isotope analog of Sulfoxaflor. Sulfoxaflor, is a new insecticide which acts as an insect neurotoxin, and is the only member of class of chemicals called the sulfoximines which act on the central nervous system of insects with much lower toxicity to mammals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anon, IP.com J., 12, 19 (2011)

Applications Diphenyl Phthalate-3,4,5,6-d4 (CAS# 1398065-61-6) is a useful isotopically labeled research compound.

Applications Trimethyl-d9-sulfonium Iodide (CAS# 106776-17-4) is a useful isotopically labeled research compound.

Applications N-Methyl-N-nitroso Urea-d6 is the labelled form of N-Methyl-N-nitroso Urea (M325815), which is a precursor of Diazomethane. It has a cytotoxicity effect.
References Huggins, C., et al.: J. Exp. Med., 131, 321 (1970); Gullino, P.M., et al.: J. Natl. Cancer Inst., 54, 401 (1975)

Applications Fenpropidin-d10 is the labeled analogue of Fenpropidin (F249470), a fungicide.
References Leroux, P. Walker, A.: Eur. J. Plant Path., 135, 683 (2013); Zhao, H., et. al.: Ecotox. Environ. Safe., 77, 52 (2012)

Applications A labelled active ingredient formulation to prepare agrochemicals and drugs in amorphous form.
References Blair, A.M., et al.: J. Agr. Sci., 139, 385 (2002),

Applications Strobilurin fungicide; inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Agricultural fungicide. Used in Pesticide detection.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),

Applications Myristic Acid (D27, 98%) (cas# 60658-41-5) is a useful research chemical.

Applications N-Boc-piperazine-d8 is a useful synthetic intermediate for the preparation of labelled compounds.

Applications n-Dotriacontane-d66 (CAS# 62369-68-0) is a useful isotopically labelled research compound. It has been studied as a potential generator to supply charged particles to plastic nuclear track detectors for high-energy neutrons.
References Oda, K., et al.: Radiation Measurements, 36, 119 (2003)

Applications Labelled Propylparaben. An antimicrobial agent used in cosmetic products.
References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),

Applications 5,5-(Diphenyl-d10) Hydantoin is deuterium labelled Diphenylhydantoin (D491650), which is an anticonvulsant agent that suppresses abnormal brain activity associated with seizure. Diphenylhydantoin is used to treat ulcers, epidermolysis bullosa, chorea, Parkinson’s syndrome, trigeminal neuralgia, acute alcoholism, and inflammatory conditions (1,2).
References (1) Kim, S. H., et al.: Birth Defects Res B Dev Reprod Toxicol. 95, 337 (2012)(2) Younes, N., et al.: Dermatol Online J. 12, 5 (2006)

Applications 2-Methyl-d3-pyridine (CAS# 10259-19-5) is a useful isotopically labeled research compound.

Applications Bentazon-d7 is deuterium labelled Bentazon (B120580), which is a herbicide.
References Ghirardello, D., et al.: Environ. Sci. Technol., 44, 9010 (2010), Frihauf, J., et al.: Weed Technol., 24, 262 (2010), Rotroff, D., et al.: Toxicol. Sci., 117, 348 (2010),

Applications 1,2-Propanediol-d6 is the d6 labelled analogue of 1,2-Propanediol (P760310) which is used in the preparation of polymers, existing as a linker unit. Also used in the preparation of colchine derivatives as anticancer agents.
References Wayakron Phetphaisit, C. et al.: Int. J. Ad. Adhesion. 41, 127 (2013); Shen, L. et al.: Asian J. Chem., 25, 3294 (2013);

Applications DMSO is a very common aprotic solvent that is used in a variety of organic chemical reactions and spectroscopic analyses.
References Vasseur, A. et al.: J. Org. Chem., 77, 5751 (2012); Kim, D.W. et al.: J. Org. Chem., 68, 4281 (2003);

Applications Diethanolamine similar to triethanolamine (T775580) is used as a surfactant. It also has the potential to be a corrosion inhibitor by means of chemisorption. This is the labelled analog.
References Bhajiwala, H.M et al.: Bull. Electrochem., 17, 441 (2001); Yu, J. et al.: Thin. Solid. Films., 379, 7 (2000);

Applications O,O-Di(Ethyl-d5)phosphate Sodium Salt is labelled Diethyl Phosphate Sodium Salt (D444720) which is used in a cosmetic composition for treating keratin materials, for example, keratin fibers such as the hair.

Applications Labelled Disulfiram. It is used as rubber accelerator; vulcanizer; seed disinfectant; fungicide; alcohol deterrent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Child, C., et al.: Acta Pharmacol. Toxicol., 8, 305 (1952), Nash, N.G., et al.: Anal. Profiles Drug Subs., 4, 168 (1975),

Applications cis-1,2,3,6-Tetrahydrophthalimide-3,3,4,5,6,6-d6 (CAS# 203578-24-9) is a useful isotopically labeled research compound.

Applications Cyclopropyl-d5-amine is labelled Cyclopopylamine (C989140) which can inactivate major human drug-metabolizing cytochromes P450 enzymes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shaffer C., et al.: J. Am. Chem. Soc., 123, 8502 (2001); Polasek, T., et al.: Brit. J. Clin. Pharmaco., 61, 570 (2006)

Applications Isosilybin A+B mixture - d3 is the isotope labelled mixture of Isosilybin A and Isosilybin B. Isosilybin (I901000) is useful in the treatment of liver disease.
References Parthasarathy, M.R., et al.: Phytochemistry, 18, 506 (1979),

Applications A labelled metabolite of ethanol in humans and a potential biomarker of acute alcohol intake.
References Jones, A., et al.: Forensic Sci. Int., 45, 217 (1990), Schmitt, G., et al.: J. Anal. Toxicol., 19, 91 (1995), Dahl, H., et al.: J. Anal. Toxicol., 26, 201 (2002), Stephanson, N., et al.: Ther. Drug Monit., 24, 645 (2002), Helander, A., et al.: Clin. Chem., 50, 936 (2004),

Applications 25-Hydroxyvitamin D2 (6,19,19-D3,97%) 100 Ug/Ml In Ethanol (cas# 1217467-39-4) is a useful research chemical.

Applications Propanoic-13C3 Acid is labelled Propionic Acid (P786360) which is used in the synthesis of novel inhibitors of signal transducer and activator of transcription 3 signaling pathway in the potential treatment of human cancers. In addition it is used in the synthesis of morphans.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, M. et al.: Eur. J. Med. Chem., 62, 301 (2013); Bradshaw, B. et al.: Org. Lett., 15, 2458 (2013)

Applications Labelled Sodium DL Lactate used as coatings in the food industry, providing antimicrobial resistance
References Zhang, H. et al.: J. Food Sci., 74, M418 (2009); Jiang, Z. et al.: J. Food Sci., 76, M22 (2011);

Applications 4-Hydroxyphenylacetic-d6 acid is deuterium labelled 4-hydroxyphenylacetic acid (H949060), which is a compound found in olive oil.
References Shu, Y., et al.: Guangdong Huagong, 37, 108 (2010); Papadopoulos, G., et al.: J Am Oil Chem Soc, 68, 669 (1991),

Applications N-Acetyl-S-(3-hydroxypropyl-1,1,2,2,3,3-D6)cysteine Dicyclohexylammonium Salt is labelled N-Acetyl-S-(3-hydroxypropyl)cysteine Dicyclohexylammonium Salt (A179075), which is a metabolite of halopropanes.
References Barnsley, E.A.: Biochem. J., 100, 362 (1966)

Applications n-Hexatriacontane-d74 (CAS# 16416-34-5) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications rac-Propranolol-d7, is the labeled analogue of Propranolol (P831800), a β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
References Bond, et al.: Nature, 213, 721 (1967), Hansteen, V., et al.: Br. Med. J., 284, 155 (1982), Diamond, S., et al.: J. Clin. Pharmacol., 28, 193 (1988),

Applications A labelled thioxanthone derivative useful as photoinitiators.
References le Fur, Y., et al.: J. Agric. Food Chem., 47, 2860 (1999), Sanz, M., et al.: Food Chem., 84, 133 (2004), Herent, M., et al.: J. Pharm. Biomed. Anal., 43, 886 (2007),

Stability Hygroscopic
Applications N,N'-Diphenylguanidine-d10 is the labeled version of 1,3-Diphenylguanidine (CAS 102-06-7), which is a useful intermediate. N,N'-Diphenylguanidine-d10 is also a rubber vulcanizing acclerator.

Applications N-(2-Hydroxyethyl)nitotinamide-d4 is labelled N-(2-Hydroxyethyl)nitotinamide (H942365), an intermediate used to prepare oxadiazole oxide derivatives as vasodilators. It is also a derivative of Nicorandil (N398500) which is an antiaginal.
References Boschi, D., et al.: Bioorg. Med. Chem., 8, 1727 (2000); Nagai, H., et al.: Chem. Pharm. Bull., 32, 1063 (1984); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)

Applications Labelled O,O-Diethyl Dithiophosphate (D444265). Used in the synthesis of novel phosphorothioates and phosphorodithioates as cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Millard, C., et al.: J. Neurochem., 64, 1909 (1995), Nicolet, Y., et al.: J. Biol. Chem., 278, 41141 (2003), Casida, J., et al.: Chem. Res. Toxicol., 17, 983 (2004),

Applications 6-Nitrodopamine-d4 is the labeled analogue of 6-Nitrodopamine(N493722), a reagent used in the detection of cancer biomarker prostate specific antigen (PSA).
References Li, H., et. al.: Biosensors Bioelectronics, 26, 3044 (2011)

Applications Intermediate in the preparation of labelled Modafinil (M482500).
References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),

Applications Regorafenib-d3 is the isotope labelled analog of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM and is useful for the treatment of inflammation. Also an anti-proliferative agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)

Applications N,N-Dimethyl-p-phenylenediamine-d6 is labelled N,N-Dimethyl-p-phenylenediamine (DMPD) (D476760) which has been used to n-dope bilayer graphene (BG) along with p-dope of tetracyanoethylene bilayer graphene to increase the band gap of DMPD/BG. N,N-Dimethyl-p-phenylenediamine (DMPD) has been shown to inhibit corrosion of mild steel in a sulphuric acid medium.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, T.H., et. al.: J. Phys. Chem. C., 117, 12873 (2013); Singh, K.U., Dubey, R.S.: Int. J. Chem., 1, 366 (2012)

Applications Ademethionine-d3 1,4-Butanedisulfonate, is a labeled analogue of Ademethionine 1,4-Butanedisulfonate (A280355), used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts.

Stability Moisture Sensitive
Applications Isotope labelled Potassium Thiocyanate has been used as a catalyst in a one-pot reaction of dialkyl acetylenedicarboxylates with indane-1,3-dione. Potassium Thiocyanate has been used as a selective bacterial inhibitor to create ESS-3 broth to allow co-​enrichment of the target pathogens and suppress growth of some non-​target pathogens
References Hassanabadi, A., Zhiani, R., et. al.: J. Chem. Res., 37, 458 (2013); Zhang, Q., et. al.: Plant. Biotech., 29, 103 (2012)

Applications Glutaric Acid (2,2,4,4-D4, 98%) (cas# 19136-99-3) is a useful research chemical.

Applications Bis(4-hydroxyphenyl) Sulfone-d4 is the isotope labelled compound commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.
References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);

Applications Isotope labelled Sodium β-Hydroxyethoxyacetate is used in the synthesis of polymer microspheres that are magnetized and are used for enzyme catalysis or bioaffinity separations.
References Horak, D. et al.: Macromol. Biosci., 12, 647 (2012); Pestov, A. et al.: Russ. J. Coord. Chem., 38, 738 (2012);

Applications 1,4-Butane-2,2,3,3-d4-diamine 2HCl (CAS# 88972-24-1) is a useful isotopically labeled research compound.

Applications A labelled metabolite of Mazindol. An imidazolinylphenyl ketone derivatives as antidepressants and diuretics.
References Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001), Murray, S., et al.: Xenobiotica, 31, 135 (2001), Lewis, D., et al.: Drug Metab. Rev., 34, 55 (2002), de Graaf, C., et al.: J. Med. Chem., 48, 2725 (2005),

Applications Bezafibrate-d4 (cas# 1189452-53-6) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications Isotope labelled Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.

Stability Hygroscopic
Applications Labelled Cyromazine (C989300). Insect growth regulator. Insecticide.
References Hall, R.D., et al.: J. Econ. Entomol., 73, 564 (1980), Hart, R.J., et al.: Aust. Vet. J., 59, 104 (1982),

Applications D-Tyrosine-d2 is deuterium labelled D-Tyrosine (T899970). D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic polypropylene surfaces.
References Li, Ji. et al.: Chin. Chem. Lett., 23, 647 (2012); Xu, H. et al.: Water Res., 45, 5796 (2011); Ke, W. et al.: Antimicrob. Agents Chemother., 55, 174 (2011)

Applications Labelled Sulfamonomethoxine. Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.
References Bridges, et al.: Biochem. J., et al.: 96, 829 (1965), Hong, Y.-L., et al.: Antimicrob. Agents Chemother., 39, 1756 (1995)

Applications A labelled inactive metabolite of Prasugrel (P701150).
References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);

Applications Used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smyth, H.F., et al.: J. Ind. Hyg. Toxicol., 30, 63 (1948),

Applications Anthracene-d10 is an isotope labelled analogue of Anthracene (A678400), an polycyclic aromatic hydrocarbon found readily as an component in coal tar. Anthracene is also used in the preparation of various dyes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Isotope labelled 2-Toluidine (T536205) is a carcinogenic and toxic aromatic amine and is a potential bladder cancer risk, surmised from urine assessment and analysis (1). It is contained in hair dye, henna and dyed hair samples (2,3). Possible mutagen (4). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. El-Bayoumy, K. et al.: Cancer Res. 1986 Dec;46(12 Pt 1):6064-7.2. Turesky R. et al.: Chem. Res. Toxicol. 2003 Sep;16(9):1162-73.3. Andrew, A. et al.: Int. J. Cancer. 2004 Apr 20;109(4):581-6.4. Kirkland, D. et al.: Mutat. Res. 2005 Dec 30;588(2):88-105.

Applications Chloroform-13C is a ubiquitous trichlorinated organohalide solvent. It is used in the preparation of stable isotope-labeled precursors for the synthesis of capsaicinoids, capsinoids and capsiconinoids.
References Kobata, K., et al.: Biosci., Biotechnol., Biochem., 75, 1611 (2011)

Applications L-(+)-Lactic Acid-13C3 Sodium Salt is the isotope labelled analog of L-(+)-Lactic Acid Sodium Salt. Sodium Salt of Lactic Acid (L113500). L-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and other organs and body fluids.
References Borsook, et al.: J. Biol. Chem., 102, 449 (1933); Brin, M., et al.: Ann. N.Y. Acad. Sci., 119, 851 (1965);

Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.
References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)

Applications Indole-4,5,6,7-d4 is a labelled analogue of Indole (I577320), which can be used in perfumes and in the synthesis of tryptophan. It is also an intermediate in synthesizing Indoleacetic Acid-13C6 (I577343), which has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);

Applications Labelled N-Nitrosopiperidine (N545370). A carcinogenic nitrosocompound.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bos, J., et al.: Cancer Res., 49, 4682 (1989), Wong, H., et al.: Carcinogenesis, 24, 291 (2003), Gonzalez-Mancebo, S., et al.: Mutat. Res., 558, 45 (2004), Gonzalez, M., et al.: Bioorg. Med. Chem., 13, 601 (2005),

Applications Labelled Iprodione. Fungicide.
References Lacroix, L., et al.: Phytiatr.-Phytopharm., 23, 165 (1974), Brenneman, T.B., et al.: Plant Dis., 71, 546 (1987),

Applications Theobromine-d3 (7-methyl-d3) is deuterium labelled theobromine, which is a metabolite of caffeine.
References Suto, M., et al.: Anticancer Drug Des., 6, 107 (1991); Burkart, V., et al.: Nat. Med., 5, 314 (1999); Hassa, P., et al.: J. Biol. Chem., 278, 45145 2003); Veres, B., et al.: J. Pharmacol. Exp. Ther., 310, 247 (2004)

Applications A labelled acetylene glycol derivative. It is used in water-based coatings and has both antifoaming and surfactant properties. It is highly toxic and have been found in acrylic adhesives used for food packaging multilayers manufacturing.
References Schwartz, J. et al.: J. Coat. Tecnhol., 67, 21 (1995); Chinoy, N.F. et al.: Polym. Paint Colour J., 175, 438 (1985);

Applications Nordihydrocapsaicin-d3 is labelled Nordihydrocapsaicin (N672600) which is a capsaicinoid and analog and congener of capsaicin in chili peppers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)

Applications Isotope labelled analogue of p-Tolyl Sulfate Potassium Salt (T536805), a representative retained toxin that shows a high level of toxicity.
References Cuoghi, A., et al.: Anal. Bioanal. Chem., 404, 2097 (2012); Wu, I.W., et al.: Nehphrol. Dial. Transplan., 27, 1169 (2012);

Applications A labelled form of Fenoxycarb (F248870), a carbamate insect growth regulator by preventing immature insects from reaching maturity by mimicking juvenile hormone. Used as a standard for Pesticide detection. Fenoxycarb is also used in cannabis testing kits as a component of pesticide mixes (P698235).
References El-Saeid, M.H., et al.: J. Chem., 10, (2013); Coors, A., et al.: Environ. Toxicol. Chem., 31, 1239 (2012);

Applications 9-Nitroanthracene-d9 (CAS# 220381-38-4) is a useful isotopically labelled research compound. It could be useful for analytical studies that involve detecting nitrated polycyclic aromatic hydrocarbons.
References Siegmund, B., et al.: Anal. Bioanal. Chem., 375, 175 (2003)

Stability Hygroscopic
Applications N-Ethyl Benzamid-3-carboxylate-d5 is the isotope labelled analog of N-Ethyl Benzamid-3-carboxylate. N-Ethyl Benzamid-3-carboxylate is an impurity of Deet (D228500) which is an insect repellent.
References Gilbert, I.H., et al.: J. Econ. Entomol., 48, 741 (1955), Ambrose, A.M., et al.: Toxicol. Appl. Pharmacol., 1, 97 (1959), Blomquist, L., Acta Pharmacol. Toxicol., 41, 235 (1977), Yeung, J.M., et al.: Drug Metab. Dispos., 16, 600 (1988),

Applications Oxalic Acid, Disodium Salt (1,2-13c2, 99%) (cas# 260429-91-2) is a useful research chemical.

Applications 4,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C2 is a labelled analogue of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blank, I., et al.: Prog. Flav. Prec. Stud., No vol. given, 103 (1993); Guerra, P. & Yaylayan, V.: J. Agr. Food Chem., 59, 4699 (2011); Mackenzie, D. & Woolf, L.: Brit. Med. J., 1, 90 (1959); Podebrad, F., et al.: J. Inh. Metab. Dis., 22, 107 (1999)

Applications 4-Desacetamido-4-chloro Andarine-D4 is a labelled analogue of 4-Desacetamido-4-chloro Andarine (D289535). 4-Desacetamido-4-chloro Andarine is a Selective Androgen Receptor Modulator (SARM) that has potential use for treatment of androgen related diseases such as muscle wasting and osteoporosis. 4-Desacetamido-4-chloro Andarine also a derivative of Andarine (A637470), a non-steroidal SARM that is used by athletes to enhance performance.
References Jones, A., et al.: Endocrinology, 150, 385 (2009); Marhefka, C., et al.: J. Med. Chem., 47, 993 (2004); Thomas, A., et al.: Rapid Comm. Mass Spec., 24, 1124 (2010)

Applications o-Anisidine is a highly toxic environmental pollutant and digestive system carcinogen. It is also a toxin that has been identified to be present in cigarettes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Coggins, C.R.E. et al.: Inhal. Toxicol., 23, 41 (2011); Dracinska, H. et al.: Neuroendorinol. Lett., 27, 9 (2006); Naiman, K. et al.: Neuroendocrinol. Lett., 31, 36 (2010);

Applications Labeled Sucrose (S697000). Yuanzhen sugar is a polysaccharide polymer, containing a certain amount of fructooligosaccharides.
References Watanabe, T., et al.: Biosci. Biotech. Biochem., 72, 3167 (2008), You, Y., et al.: J. Agric. Food Chem., 57, 709 (2009),

Applications Furfural-3,4,5-d3 (CAS# 53599-40-9) is a useful isotopically labeled research compound.

Stability Air Sensitive
Applications 2,4-Xylidine-d6 is labelled 2,4-Xylidine (X749690) which is an aniline derived chemical reagent used in the synthesis of antiarrhythmic compounds. It is also used as a reactant in the synthesis of anticonvulsants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kalinin, D. et al.: Eur. J. Med. Chem., 63, 144 (2013); Ragavendran, J. et al.: Eur. J. Med. Chem., 42, 146 (2007);

Applications Simazine-d10 is the isotope labelled analog of Simazine (S465900); a selective pre-emergence herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bailey, G.W., et al.: Residue Rev., 10, 97 (1965); Chun, O., et al.: Food Chem. Toxicol., 41, 1063 (2003); Berrada, H., et al.: Food Control., 21, 36 (2010)

Applications Thiobencarb-d10 (diethyl-d10) (CAS# 1219804-12-2) is a useful isotopically labeled research compound.

Applications Isotope Labelled 1-Nitrosopyrrolidine (N545950), which is one of the N-nitroso compounds (NOCs) implicated in human colon carcinogenesis, but the toxicological mechanisms involved have not been elucidated. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Singer, S. et al.: J. Med. Chem. 1985 Aug;28(8):1088-93.2. Tomatis, L. et al.: Carcinogenesis. 1997 Jan;18(1):97-105.3. Helguera, A. et al.: Toxicol Appl Pharmacol. 2007 Jun 1;221(2):189-202.

Applications Sodium Formate (13c, 99%; D, 98%) (cas# 1215684-17-5) is a useful research chemical.

Applications Acetoin-13C4 is the labeled analogue of the unlabeled (A163775), which is used in food flavoring and fragrances and is also found in some fruits and vegetables.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dutta, S.M. et al.: Ind. J. Dairy Sci., 24, 107 (1971);

Applications Labelled Propafenone (P757500) impurity.
References Kitagawa, S., et al.: Biol. Pharm. Bull., 29, 1 (2006), Boccard, J., et al.: Eur. J. Pharm. Sci., 36, 254 (2009)

Applications T-705RTP-13C5 Sodium Salt is a labeled salt derivative of T-705 (F103350) which has activity against the lethal H5N1 influenza A viruses.
References Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005); Kiso, M., et al.: Proc. Natl. Acad. Sci. U.S.A., 107, 882 (2010)

Applications 1,4-Butane-1,1,2,2,3,3,4,4-d8-diamine (D416027) is a labelled isotope of 1,4-Diaminobutane (D416025). It is an amino acid degradation product. Used in the preparation of hexahydropyrimidines as novel hepatitis C virus inhibitors. Also a reagent in the synthesis of antibacterial castor oil-based polyurethane membranes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hwang, J. et al.: Eur. J. Med. Chem., 70, 315 (2013); Yari, A. et al.: J. Biomed. Mat. Res., 102A, 84 (2014);

Applications Pemetrexed-13C5 Disodium Salt, is the labeled analogue of Pemetrexed Disodium (P219500), used as Antineoplastic agent.
References McDonald, A.C., et al.: Clin. Cancer Res., 4, 605 (1998), John, W., et al.: Cancer, 88, 1807 (2000), Miller, K.D., et al.: Ann. Oncol., 11, 101 (2000),

Applications Thiodiglycolic Acid-d4 acts as a reagent for the synthesis of metabolites of S-carboxymethyl-L-cysteine and S-methyl-L-Cysteine and of some isotoically labelled (2H, 13C) analogs.
References Meese, C. O., et al.: Archiv der Pharmazie, 323, 957 (1990)

Applications 2-Butan-3,3,4,4,4-d5-ol was used to prepare and oxidize 3,3-disubstituted cyclobutenes.
References Curry, M., et al.: J. Chem. Soc., 10, 1391 (1980)

Applications Sodium Acetate-d3, is the labeled analogue of Sodium Acetate, the sodium salt of acetic acid, with a wide range of uses. Sodium Acetate is used in the textile industry to neutralize sulfuric acid waste streams, and as a photoresist while using aniline dyes. Sodium Acetate may be added to foods as a seasoning.
References Clayden, j., et al.: Org. Chem., 1st ed. (2001);