Deuterated Compounds

Applications N,N-Diisopropylamine-d14 is used in the synthesis of trideuterated propantheline bromide;Also, it is an intermediate used in the synthesis of Disopyramide-d14 Tosylate Salt (D493452), which is an anti-arrhythmic (class IA). Sodium channel blocker.
References Buckley, P. H., et al.: J. Label. Compd. Radiopharm., 15, 657-664 (1978); Adelstein, et al.: J. Med. Chem., 16, 309 (1973), Czeisler, J.L., et al.: J. Pharm. Sci., 74, 750 (1985), Taylor, E.H., et al.: Ann. Clin. Lab. Sci., 16, 289 (1986)

Applications 1,1-Dimethyl-d6-urea (CAS# 1219802-32-0) is a useful isotopically labeled research compound.

Applications 3-Pentyl-2,2,3,4,4-d5 Alcohol (CAS# 144032-75-7) is a useful isotopically labeled research compound.

Applications 1-Bromopropane-2,2-d2 (CAS# 40422-15-9) is a useful isotopically labeled research compound.

Applications 1,3-Propane-d6-dithiol (CAS# 1219803-51-6) is a useful isotopically labeled research compound.

Applications N-Acetyl-DL-alanine-3,3,3-d3 is an isotopic analog of N-Acetyl-DL-alanine (A167965), a derivative of DL-Alanine (A481400) and is used as a reagent in the synthesis of potent new agents for the treatment of epilepsy.
References Conley, J.D., et al.: J. Med. Chem., 30, 567 (1987)

Applications N-Boc-2-(methylthio)ethylamine-d3 is the isotope labelled analog of N-Boc-2-(methylthio)ethylamine (B657055); a compound used as a reagent in the synthesis of anthranilic diamide insecticides and new glycopeptidomimetics based on N-substituted oligoglycines bearing N-linked lactoside side chains.
References Hua, X., et al.: Austr. J. Chem., 67, 1491 (2014); Saha, U.K., et al.: J. Chem. Soc. Chem. Comm., no vol., 2571 (1995)

Applications Octadecanoic-9,9,10,10-d4 Acid (CAS# 130048-57-6) is a useful isotopically labeled research compound.

Applications Used in the preparation of labelled indolizine compounds for use in antifungal combination therapy.

Applications 3,5-Dihexanamido-2,4,6-triiodo-benzoic Acid-d22 is the isotope labelled analog of 3,5-Dihexanamido-2,4,6-triiodo-benzoic Acid (D448150); a derivative of 3,5-Diamino-2,4,6-triiodobenzoic Acid (D416820) which is a metabolite of Diatrizoate with mutagenic and cytotoxic properties.
References Kalsch, W., et al.: Sci. Total Environ., 225, 143 (1999); Parkesh, R., et al.: Org. Biomol. Chem., 4, 3611 (2006)

Applications Labelled 1-Hexadecene. 1-Hexadecene is one of the alpha olefins used as comonomers in polymer such as low density polyethylenes for the properties of lighter, thinner, better flexibility and more tearing resistance.
References Conde, R., et al.: Phytomedicine, 18, 1197 (2011),

Applications n-Hexadecyltrimethylammonium-d42 Chloride (CAS# 2095863-88-8) is a useful isotopically labeled research compound.

Applications Methoxy Deethoxy Loteprednol Etabonate-d5 is labelled Methoxy Deethoxy Loteprednol Etabonate (M262230), a derivative of Loteprednol Etabonate (L471400) which is an ophthalmic corticosteroid.
References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)

Applications Benzyl-2,3,4,5,6-D5 Alcohol is an isotopically labeled analog of Benzyl Alcohol (T536635), which is used in the synthesis of Cephalosporolide B as a versatile biomimetic synthetic precursor for chemical synthesis of other cephalosporides.
References Song, L. et al.: Org. Lett., 15, 5850 (2013);

Applications Estradiol 17-Palmitate-d31 is the isotope analog of Estradiol 17-Palmitate. Estradiol 17-Palmitate is a metabolite of estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.
References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),