Deuterated Compounds

<p>Applications (±)-(1-Bromoethyl-2,2,2-d3)benzene (CAS# 23088-42-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications tert-Butyl-d9-phosphine is the labeled analogue of tert-Butylphosphine (B809330), a reactant in the synthesis of phosphine ligands in metal complexes.<br>References Wiedner, E.S., et. al.: Organometallics, 29, 5390 (2010)<br></p>

<p>Applications N-Ethylaniline-d5 is labelled N-Ethylaniline (E899362) which is a versatile organic building block used for the synthesis of various pharmaceutical and biologically active compounds. It can be used for the synthesis of benzenesulfonamides as inhibitors of microsomal prostaglandin E2 synthase 1 (mPGES-1) in mice and in humans as potential anti-inflammatory agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hanke, Th., et al.: Biorg. Med. Chem., 21 (24), 7874 (2013)<br></p>

<p>Applications Hexanedioyl-d8 Chloride (CAS# 284487-62-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Bis(2-isopropylphenyl) Phenyl Phosphate-d5 is the deuterated form of Bis(2-isopropylphenyl) Phenyl Phosphate (B451445), which is a triaryl phosphate used as plasticizers in polyvinyl chloride (PVC) as well as a flame retardant. Studies show that Bis(2-isopropylphenyl) Phenyl Phosphate inhibits the human androgen receptor.<br>References Duke, A.J.: Chimia, 32, 457 (1978); Honkakoski, P. et al.: Biochem. Pharmacol., 67, 97 (2004); Nobile, E.R. et al.: Bull. Environ. Contam. Toxicol., 25, 755 (1980);<br></p>

<p>Stability Hygroscopic<br>Applications 6-N-Acetyl-L-lysine-d8 is an isotopic analog of N-Acetyl-L-lysine (E588725(P)), which is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.<br>References Sanchez-Lopez, E., et al.: J. Pharm. Biomed. Anal., 140, 313 (2017)<br></p>

<p>Applications Furfuryl-d5 Alcohol (CAS# 1398065-62-7) is a useful isotopically labeled research compound.<br></p>

<p>Stability Extremely Volatile<br>Applications 1-Hexene-d3, an isotopically labelled 1-Hexene, is used in the synthesis of ethylene polymers and copolymers. An olefin used to synthesize diols through oxidation reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tao, X. et al.: Organometal., 32, 4185 (2013); Clerici, M. et al.: J. Catal., 140, 71 (1993);<br></p>

<p>Applications Glyceryl Tri(octadecanoate-d35) (CAS# 125941-88-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled Methylboronic Acid is an methylated derivative of boronic acid, an building block towards various intermediates in suzuki coupling.<br>References Baker, J. O., et al.: Biochem.. 22, 2098 (1983); Garner, C.W., et al.: J. Biol. Chem., 255, 5064 (1980);<br></p>

<p>Applications Pentanedioic-d6 Anhydride (CAS# 1219794-53-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.<br>References Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009); Springhorn, C. et al.: J. Clin. Endocrinol. Metab., 97, 4640 (2012); Hashimoto, K. et al.: J. Clin. Endocrinol. Metab., 97, 3016 (2012); Avelange, M. et al.: Plant. Phys., 94, 1157 (1990); Cramer, C. et al.: J. Chem. Soc., 115, 5745 (1993);<br></p>

<p>Applications Ethyl-alpha,alpha-d2-benzene (CAS# 1861-01-4) is a useful isotopically labeled research compound.<br></p>