Deuterated Compounds

Applications 6-Nitrodopamine-d4 is the labeled analogue of 6-Nitrodopamine(N493722), a reagent used in the detection of cancer biomarker prostate specific antigen (PSA).
References Li, H., et. al.: Biosensors Bioelectronics, 26, 3044 (2011)

Applications Acridine (D9, 98%) (cas# 34749-75-2) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Dodecane-d26, is the labeled analogue of Dodecane (D494625), which is used in the synthesis of triblock polymers that deliver nanoparticles to the oil/water interface and degrade non-tocxc non-aqueous liquids.
References Saleh, N. et al.: Nano. Lett., 2489, 5 (2005); Scarso, A. et al.: J. Am. Chem. Soc., 126, 13512 (2004);

Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.
References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),

Applications cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5 is an isotopic analog of cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester is an ethyl analog of cis-7,10,13,16-Docosatetraenoic Acid (D494510). cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies.
References Mirnikjoo, B. et al.: J. Biol. Chem., 276, 10888 (2001);

Applications Isotope labelled Phosphoric Acid Tributyl Ester is used as a solvent in the solvent-detergent method for production of immunoglobulin for inactivation of viruses with lipid envelope on the model of duck hepatitis B virus. It is also used as a ligand in the extraction of lanthanide ions from solid and liquid materials by supercritical CO2.
References Zubkova, N., et al.: Bull. Exp. Biol. Med., 155, 821 (2013); Lin, Y., et al.: Anal. Chem., 66, 1971(1994)

Stability Hygroscopic
Applications Hydrochloride Salt of 2-Methyl-3-isothiazolone-d3, a pesticidal substituted 3-isothiazolinone.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Thierse, H., et al.: J. Immunol., 172, 1926 (2004), Nilsson, A., et al.: Chem. Res. Toxicol., 18, 308 (2005), Nitsche, J., eet al.: J. Pharm. Sci., 95, 649 (2006),

Applications 2-Amino-ethan-1,1,2,2-d4-ol is labelled Ethanolamine (E676500) which is used in the preparation of various pharmaceutical compounds and inhibitors. Substituted carboxamides are synthesized using Ethanolamine that show potent antitumor activity. Also used in the synthesis of aminoquinolones which display anti-plasmodial activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);

Applications A labelled metabolite of Temozolomide, an antineoplastic.

Applications 5-(4-Chlorobutyl)-1-cyclohexyltetrazole-d11 (cas# 1073608-19-1) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications Isotope labelled Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.

Applications 1,4-Dichlorobutane-d8 (CAS# 83547-96-0) is a useful isotopically labeled research compound.

Applications Glutaric Acid (2,2,4,4-D4, 98%) (cas# 19136-99-3) is a useful research chemical.

Applications 2-Benzothiazolethiol-d4 (cas# 1346598-64-8) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications A labelled form of Catechol (C215175) and has been used in the characterization of surface inclusion of unidirectional molecular motors in hexagonal tris(o-phenylene)cyclotriphosphazene.
References Kaleta, J.; et al.: J. Am. Chem. Soc., 139, 10486 (2017).

Applications A labelled metabolite of Mazindol. An imidazolinylphenyl ketone derivatives as antidepressants and diuretics.
References Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001), Murray, S., et al.: Xenobiotica, 31, 135 (2001), Lewis, D., et al.: Drug Metab. Rev., 34, 55 (2002), de Graaf, C., et al.: J. Med. Chem., 48, 2725 (2005),

Applications 1-Pyren-2,3,4,5,6,7,8,9,10-d9-amine is derived from Pyrene-d10 (P849002), which is labelled Pyrene. Occurs in coal tar. Also obtained by the destructive hydrogenation of hard coal.
References Winterstein, et al.: Z. Physiol. Chem., 230, 162 (1934)