Deuterated Compounds

<p>Applications Ethylbenzene-d10 (cas# 25837-05-2) is a useful research chemical.<br></p>

<p>Applications The primary aroma compound of red raspberries, used in perfume compositions, shampoos, cosmetics and as a food additive.<br>References Aggarwal, S., et al.: Mol. Pharmacol., 69, 195 (2006), Beekwilder, J., et al.: Biotechnol. J., 2, 1270 (2007), Akiyama, M., et al.: J. Food Sci., 72, C388 (2007),<br></p>

<p>Applications sotope labelled m-Cresol (C781915) is one of the components that make up liquid rice hull smoke, and may contribute to its anti-inflammatory effects in mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Hydroxybenzophenone-d4 is an isotopic analog of 4-Hydroxybenzophenone (H829305), a metabolite of benzophenone (B204980).<br>References Stocklinski, A. et al. Life Sciences 26, 365(1980)<br></p>

<p>Applications Isotope labelled 2-Toluidine (T536205) is a carcinogenic and toxic aromatic amine and is a potential bladder cancer risk, surmised from urine assessment and analysis (1). It is contained in hair dye, henna and dyed hair samples (2,3). Possible mutagen (4). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. El-Bayoumy, K. et al.: Cancer Res. 1986 Dec;46(12 Pt 1):6064-7.2. Turesky R. et al.: Chem. Res. Toxicol. 2003 Sep;16(9):1162-73.3. Andrew, A. et al.: Int. J. Cancer. 2004 Apr 20;109(4):581-6.4. Kirkland, D. et al.: Mutat. Res. 2005 Dec 30;588(2):88-105.<br></p>

<p>Applications Triclabendazole Sulfone-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>

<p>Applications Labelled Creatinine. The end product of creatine catabolism. Normal constituent of urine. Also found together with creatine in muscle tissues and blood. Occurs in all soils and in grain seeds and other vegetable matter. Has been found in certain fish and in crab meat extract.<br>References Folin, et al.: J. Biol. Chem., 17, 463 (1914),<br></p>

<p>Applications Butanoic-d7 Acid is a deuterated version of Butanoic Acid (B692235). Butanoic Acid, is found in milk, especially goat, sheep and buffalo milk. It can be used for the preparation of various esters, such as methyl butyrate, which has pleasant aromas or tastes and thus can be used as food and perfume additives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lupton, J. R., et al.: J. Nutrition, 134 (2), 479 (2004); Grummer, R. R., et al.: J Dairy. Sci., 74 (9),3244 (1991)<br></p>

<p>Applications Labelled Folpet (F402000). Agricultural fungicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, S., et al.: Crit. Rev. Toxicol., 40, 531 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5884 (2010),<br></p>

<p>Applications Sodium Formate (13c, 99%; D, 98%) (cas# 1215684-17-5) is a useful research chemical.<br></p>

<p>Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>

<p>Applications 4-tert-Butylphenol-D9 is the labelled analogue of 4-tert-Butylphenol (B694105). 4-tert-Butylphenol is a reactant in the preparation of (2-bromocyclopent-2-en-1-yl)phenols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Speck, K., et. al.: Org. Lett., 17, 1982 (2015)<br></p>

<p>Applications Isotope labelled 4-Chlorobenzoic Acid is a benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. It is used as a preservative.<br>References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),<br></p>

<p>Stability Light Sensitive, Volatile<br>Applications A labelled antibacterial agent.<br>References Kind, T., et al.: Anal. Biochem., 363, 185 (2007), Spratlin, J., et al.: Clin. Cancer Res., 15, 431 (2009),<br></p>

<p>Applications 2-Methyl-d3-pyridine (CAS# 10259-19-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Sodium Butyrate (13c4, 99%) (cas# 312623-84-0) is a useful research chemical.<br></p>

<p>Applications A labelled form of Catechol (C215175) and has been used in the characterization of surface inclusion of unidirectional molecular motors in hexagonal tris(o-phenylene)cyclotriphosphazene.<br>References Kaleta, J.; et al.: J. Am. Chem. Soc., 139, 10486 (2017).<br></p>

<p>Applications Tetraphenylstannane-d20 is an isotope labelled organometallic compound and an intermediate in the synthesis of isotope labelled Chlorotriphenylstannane (C4222525), a compound used in the synthesis of nano particles that bears triamide ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Isotope labelled 2-Bromoethanol is an widely used intermediate in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tian, Z., et al.: Int. J. Quant. Chem., 111, 631 (2011); Thayer, F.K., et al.: Org. Syntheses., 6, (1926);<br></p>

<p>Applications Dihydro uracil-d4 is deuterium labelled dihydro uracil (D449990). Modified nucleobases are useful molecular tools to study nucleic acid structures and to probe biological systems. Dihydro uracil has also been utilized in mechanistic studies relating to the base excision repair (BER) pathway during DNA repair.<br>References Chawla, M., et al.: Nucleic Acids Res 43, 9573 (2015); Jian, Y., et al.: J. Am. Chem. Soc. 137, 3318 (2015); Shaul, Y. D., et al.: Cell 158, 1094 (2014)<br></p>