Deuterated Compounds

Applications 4-Azidobutyl-d8-amine is the labeled analogue of 4-Azidobutylamine (A822560), which is weakly or non-mutagenic to Salmonella typhimurium.
References Owais, W.M., et. al.: Mutat. Res. Genetic Toxicol. Testing, 118, 229 (1983)

Applications Isotope labelled D-Glucitol is a sugar alcohol obtained from the reduction of glucose and is naturally found in various fruits such as apples, pears and peaches. D-Glucitol has been widely used as a sweetener, laxative, various medical applications and in cosmetic products.
References Wang, Z.J., et al.: Anal. BIoanal. Chem., 405, 3899 (2013); Vinarta, S.C., et al.: Carb. Poly., 92, 1107 (2013); Kaumanu, M.L., et al.: Soil. Biol. Biochem., 57, 644 (2013); Hailu, T., et al.: Anal. Biochem., 434, 181 (2013);

Applications trans-9-Octadecenyl phosphocholine-D9 is a labelled analogue of trans-9-Octadecenyl phosphocholine (O235600).

Applications 2-Nitropropane-1,1,1,3,3,3-d6 (CAS# 52809-86-6) is a useful isotopically labeled research compound.

Applications 1-(2-Pyridinyl)benzotriazole-15N3 (cas# 1189465-04-0) is a compound useful in organic synthesis.

Applications Ethylene Glycol Dimyristate-d4 is a deuterated version of Ethylene Glycol Dimyristate (E917560), a pearling agents for cosmetics.
References Onozaki, T., et al.: Journal of SCCJ, 15, 38-44 (1981)

Applications Glyceryl Trihexadecanoate-13C2 [1,3-Di(hexadecanoate-1-13C)] (CAS# 339080-65-8) is a useful isotopically labeled research compound.

Applications Ethyl β-Alanine-2,2,3,3-d4 Ester is an intermediate used in the synthesis of N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine-d4 (C424342), which is an isotope labelled N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine is a metabolite of Tianeptine (T436800), a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.
References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991), Nair, M. et al.: Analyst, 123, 2267 (1998)

Applications 5-Methyl-2(1H)-pyridinone-d6 is a reagent used in the preparation of substituted N-aryl pyridinones as fibrotic inhibitors.

Applications 1-Bromotridecane-1,1,2,2-d4 (CAS# 284474-45-9) is a useful isotopically labeled research compound.

Applications Terconazole-d4 is the isotope labelled analog of Terconazole (T110600); a compound used for topical treatment of mycotic vaginitis. Terconazole may also be used in vitro as a potent antifungal agent to prevent the morphogenetic transformation of yeast into the (pseudo-)mycelium form of Candida albicans.
References Cauwenbergh, G., Vanden Bossch H.: J. Reprod. Med., 34, 588 (1989); Del Palacio-Hernanz, A., et. al.: Chemioterapia, 3, 192 (1984); Van Cutsem, J., et. al.: Chemotherapy, 29, 322 (1983)