Deuterated Compounds

Applications 1,6-Dibromohexane-d12 (CAS# 169397-96-0) is a useful isotopically labeled research compound.

Applications Sodium Propionate-3,3,3-d3 (CAS# 1210410-35-7) is a useful isotopically labeled research compound. This compound can be used to demonstrate intereactions between ergosterol and amphotericin B in lipid bilayers using NMR spectroscopy to exert antifungal activity.
References Matsumori, N.,et.al., J.Am.Chem.Soc., 131,11855-11860,(2009);

Applications 4-[(Tetrahydro-2H-pyran-2-yl)oxy]-2-butyn-1-ol-1,2,3,4-13C4 is an intermediate in the synthesis of N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-13C4 (A173713). N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-13C4 is labelled N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine (A173710), which is a metabolite of butadiene.
References Heavner, D., et al.: J. Pharm. Biomed. Anal., 40, 928 (2006); Carmella, S., et al.: Chem. Res. Toxicol., 22, 734 (2009)

Applications N,N-Dimethylaniline-d11 (CAS# 85785-00-8) is a useful isotopically labeled research compound.

Applications Deferasirox Methyl Ester-d3 is the isotope labelled analog of Deferasirox Methyl Ester (D228675); a derivative of Deferasirox (D228650) which is an orally active tridentate iron chelator.
References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)

Stability Hygroscopic
Applications Propyl-d7 β-D-Glucuronide Sodium Salt is a glucuronide of a short-chained aliphatic alcohol formed via glucuronidation in human liver microsomes in vitro.
References Jurowich, S. et al.: Alcohol, 32, 187 (2004);

Applications Dibutyl Phenyl Phosphate-d5 is the deuterated form of Dibutyl Phenyl Phosphate (D429478), which is a phosphorus flame retardant additive.
References Sundkvist, A. M., et al.: Environ Monit Assess., 12, 943 (2010),

Applications 1-Bromobutane-3,3,4,4,4-d5 (CAS# 1219805-37-4) is a useful isotopically labeled research compound.

Applications 2-Bromopropane-1,1,1,2-d4 (CAS# 1219799-22-0) is a useful isotopically labeled research compound.

Applications Cholesterol-3-d1 (CAS# 51467-57-3) is a useful isotopically labeled research compound.

Applications Labelled 2-Furfurylthiol Acetate (F864600). 2-Furfurylthiol Acetate is a sulfur-substituted furan derivative used as flavouring agent. 2-Furfurylthiol Acetate is a precursor to furfurylmercaptan which is very prone to oxidation to the disulfide. We will provide a detailed procedure for the preparation of the thiol from the thioacetate with spectral data upon request.
References Engel, K., et al.: J. Agric. Food Chem., 39, 2249 (1991), Jones, M., et al.: J. Exp. Bot., 55, 1903 (2004), Gershater, M., et al.: J. Biol. Chem., 282, 21460 (2007),

Applications N2-Acetyl Acyclovir-d4 is the isotope labelled analog of N2-Acetyl Acyclovir (A168015); an impurity of Acyclovir (A192400) which is an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also an antiviral.
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)

Applications 1-Bromodecane-d21 (CAS# 98195-39-2) is a useful isotopically labeled research compound.