Organic Halides

<p>Applications Trityl Chloride is an alkyl halide commonly used in organic synthesis to introduce the trityl protecting group. Trityl Chloride is used in the preparation of S-trityl-L-cysteine (STLC), a tight-binding inhibitor of Eg5 that prevents mitotic progression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DeBonis, S. et al.: J. Med. Chem., 51, 1115 (2008); Chadwick, D.J. et al.: J. Chem. Soc. Perk. Trans. Org. Bio-Org. Chem., 1, 102 (1983);<br></p>

<p>Stability Volatile<br>Applications 1,2-Dichlorotrifluoroethyl trifluoromethyl ether (cas# 2356-53-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications DL-2,4-Diaminobutyric Acid Dihydrochloride (cas# 65427-54-5) is a useful research chemical.<br></p>

<p>Applications α-Isopropylbenzylamine Hydrochloride is used in the synthetic preparation of arylalkylamines by addition of Grignard reagents to phosphorylaldimines.<br>References Zwierzak, A., Napieraj, A.: Synthesis, 6, 930 (1999)<br></p>

<p>Applications 1,3-Dichloropropan-2-one O-Benzyl-oxime (cas# 188125-86-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 4-Chloropicolinate (cas# 24484-93-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Bromo-2-butyne is used in the synthesis of six to eight annulated ring compounds in reactions with indoles. It is also used in the preparation of Pseudopterane (+/-)-Kallolide B, a marine natural product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferrer, C. et al.: Chem. A. Eur. J. et al.: 13, 1358 (2007); Marshall, J. et al.: J. Org. Chem., 60, 796 (1995);<br></p>

<p>Applications N-Iodoacetyltyramine is used in iodine-125 labelling of various molecules for chemical analysis.<br>References Lin, C. et al.: Anal. Biochem., 179, 389 (1989);<br></p>

<p>Applications CHLOROFLUOROACETAMIDE (cas# 431-09-4) is a useful research chemical.<br></p>

<p>Applications 2-​Amino-​3-​chloro-​5-​trifluoromethylpyrid​ine acts as a reactant in the synthesis of novel imidazo[1,2-a]pyridine-coumarin hybrid molecules as inhibitors of NS5B in potential treatment of Hepititis C.<br>References vManvar, P. et al.: Tetrahedron 72, 1293 (2016);<br></p>

<p>Stability Moisture Sensitive<br>Applications Thiophosphoryl chloride is a starting material for O-ethyl dichlorothiophosphate synthesis.<br> E0<br></p>

<p>Stability Light Sensitive<br>Applications Dibromoacetonitrile is a carcinogenic nitrogenous disinfection byproduct. Dibromoacetonitrile in drinking water was linked to oral cavity cancer in rats and forestomach cancer in mice. In addition, Dibromoacetonitrile may cause oxidative damage in rat brain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, Z., et al.: Chem. Eng. J. 306, 1180 (2016); Krasner, S. W., et al.: Environ. Sci. Technol. 50, 9583 (2016); Natl Toxicol Program Tech Rep Ser. 544, 1 (2010); Klattisaksiri, P., et al.: Water Res 98, 160 (2016); Sayed, R. H., et al.: Environ Toxicol Pharmacol. 34, 849 (2012)<br></p>

<p>Applications 2-Amino-3,5-dibromobenzoic acid (cas# 609-85-8) is a useful research chemical.<br></p>

<p>Applications 9-Bromononanol (cas# 55362-80-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Bromo-2-phenylacetic acid<br></p>

<p>Stability Light Sensitive<br>Applications 1,3,5-Tris(2,3-dibromopropyl) Isocyanurate is a flame retardant that has applications in assessing potential bioaccumulation and impact on endocrine activity. It has been employed in flow-cytometric proliferation assay to determine potential estrogen-disruptive effects of flame retardants in MCF-7 cells.<br>References Krivoshiev, B. V., et al.: Toxicol In Vitro 33, 153 (2016); Liang, D., et al.: Environ Technol 37, 2292 (2016)<br></p>

<p>Applications 2,4-DINITROBENZYL BROMIDE (cas# 3013-38-5) is a useful research chemical.<br></p>

<p>Applications Ammonium Chloride is used as a main component and source of nitrogen in fertilizer.<br>References Crill, P. et al.: Soil Biol. Biochem., 26, 1331 (1994); Zaman, M. et al.: Biol. Fert. Soils, 29, 178 (1999);<br></p>

<p>Stability Unstable in Solution<br>Applications 2-(Trimethylsilyl)ethoxymethyl chloride is mostly used in organic synthesis to protect hydroxyl functionalities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lipshutz, B. &amp; Miller, T.: Tetrahedron Lett., 30, 7149 (1989); Wada, T., et al.: Tetrahedron Lett., 36, 1683 (1995)<br></p>

<p>Applications 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone is a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent.<br>References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009<br></p>

<p>Applications 1-CHLORO-3-ETHYLBENZENE (cas# 620-16-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-[(2-Chlorophenyl)(methylimino)methyl]cyclopentanol has potential use as a component of household cleaning solution products. IT is also an intermediate in the production of the cyclohexanone analogue.Ketamine (K165300) related compound.<br></p>

<p>Applications 5-Bromo-2-thiophenecarboxaldehyde is used in biological studies as anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.<br>References Prabhu, V.V., et al.: J. Immunotoxicol., 9, 341 (2012);<br></p>

<p>Applications Ethyl 2-Chloracetoacetate is used in the preparation of oxazoles and thiazoles as agonists for peroxisome proliferator-activated receptor δ. It is also used to synthesize dimethylimidazothiadiazolecarbohydrazides with anticancer activities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sznaidman, M., et al.: Bioorg. Med. chem. Lett., 13, 1517 (2003); Terzioglu, N., et al.: Eur. J. Med. Chem., 38, 781 (2003)<br></p>

<p>Applications 1H,1H,2H-Perfluoro-1-decene (cas# 21652-58-4) is a useful research chemical.<br></p>

<p>Applications 2-Amino-6-(chloromethyl)-4(3H)-pteridinone is a reagent/intermediate used in the preparation of Folic Acid (F680300) and its derivatives.<br>References Qi, Y., et al.: Faming Zhuanli Shenqing. CN 103755706 A 20140430. Apr 30, 2014;<br></p>

<p>Applications 3,5-Diiodothyronamine Hydrobromide is an intermediate in the synthesis of Thyronamines and related analogues.<br>References Hart, M. E., et al.: J. Med. Chem., 49, 1101 (2006);<br></p>

<p>Applications 3,5-Dichlorotoluene is a common chemical reactant used in the synthesis of various pharmaceuticals and biological agents. Used in the preparation of pyrazole amide derivatives as RORγ inhibitors as well as cross coupling reactions.<br>References WO Patent 2015129926 (Sep 3, 2015); Sun, X. et al.: Angew. Chem., Int. Ed., 52, 4440 (2013);<br></p>

<p>Applications 2-Bromo-4,5-dimethoxybenzoic Acid (cas# 6286-46-0) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications Tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate (cas# 19186-97-1) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications A phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications Dimethyldimyristylammonium bromide is a cationic surfactant used in the study of lipid raft domains in membranes.<br>References Uyama, M.; et al.: J. Oleo Sci., 67, 67 (2018).<br></p>

<p>Applications 2,6-Difluorobenzoylacetonitrile is used in the synthesis of thienodiazepinones which can have poor central nervous system depressant activity.<br>References Binder, D., et al.: Arch. Pharm., 313, 587 (1980)<br></p>