Organic Halides

<p>Applications CHLOROMETHYL ISOBUTYRATE (cas# 61644-18-6) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Cyclobutylmethylamine Hydrochloride<br></p>

<p>Applications 4-Chloro-1-butanol is a reagent used in the preparation of pharmaceutical compounds such as canthine analogues for their activity against HeLa cervical cells. Also used in the preparation of novel and highly potent Bryostatin, another anti-cancer agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naik, P. et al.: Tetrahedron, 69, 6545 (2013); Wender, P. et al.: J. Am. Chem. Soc., 124,13648 (2002);<br></p>

<p>Applications 3-(Chloromethyl)-2,4,6-trimethylbenzoic Acid (cas# 52411-49-1) is a useful research chemical.<br></p>

<p>Applications 2-Fluoro-5-iodobenzonitrile is a compound commonly used in synthetic chemistry and is also used as a reagent to synthesize 1-alkyl-1H-indazoles. 2-Fluoro-5-iodobenzonitrile reacts with sodium sulfide to produce mercaptobenzonitriles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, H., et al.: Tetrahedron, 19, 3907 (2013); Taldone, T., et al.: Tetrahedron Lett., 53, 2548 (2012)<br></p>

<p>Applications Methyl trans-4-Bromo-2-butenoate is used as a reagent in the synthesis of several organic compounds including that of dimethoxy ketals and ketones via electrochemical oxidative decarboxylation of malonic acids.<br>References Ma, X., et al.: Org. Lett., 17, 4690 (2015);<br></p>

<p>Applications 2-Chloro-4'-nitrobenzanilide (cas# 55501-45-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,5-Diiodothyropropionic acid is an ionotropic analog of L-thyroxine.<br></p>

<p>Applications cyclopent-2-en-1-amine hydrochloride (cas# 91469-54-4) is a useful research chemical.<br></p>

<p>Applications 2-Chloro-5-Fluoro-3-(Trifluoromethyl)Benzoic Acid (cas# 1805955-65-0) is a useful research chemical.<br></p>

<p>Applications 2-Bromobutane is used in the various organic synthesis, existing as a grignard reagent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Girard, P. et al.: J. Am. Chem. Soc., 102, 2693 (1980); Apsel, B. et al.: Nat. Chem. Biol., 4, 691 (2008);<br></p>

<p>Applications (2-Carboxyethyl)-triphenylphosphonium Chloride (cas# 36626-29-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Dichloroacetonitrile is commonly used with gas chromatography-mass spectrometry instrument to evaluate and quantify the common halogenated disinfection by products using the headspace technique.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Montesinos, I., et al.: J. Chromatogr. A., 1310 113 (2013)<br></p>

<p>Applications 3,4-Dimethyl-benzamidine hydrochloride (cas# 112072-09-0) is a useful research chemical.<br></p>

<p>Applications Hydrobromide salt of Triphenylphosphine, used in the preparation of uridine derivatives as substrate donor analogs of UDP-sugars for glycosyltransferases. Also used in the preparation of tensioactive and antibacterial deoxyglycoside compounds via catalysis.<br>References Wandzik, I. et al.: Bioorg. Chem., 37, 211 (2009); Martins, A. et al.: Eur. J. Org. Chem., 2014, 1448, 2013<br></p>

<p>Applications 2-Bromoiodobenzene was used in the synthesis of diarylamines. It was also a reactant used in Suzuki Coupling reactions.<br>References Buden, M., et al.: J. Org. Chem., 74, 4490 (2009); Wolfe, J., et al.: J. Am. Chem. Soc., 121, 9550 (1999)<br></p>

<p>Applications 2-Bromo-1-(4-dimethylaminophenyl)ethanone<br></p>

<p>Applications 5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions<br></p>

<p>Applications 2-(2,4-Difluorophenyl)-1,2,3-propanetriol is used as a reagent in the synthesis of glycerol derivatives as intermediates for antifungal phenyltriazolylpropanediol derivatives. Also an impurity of the antifungal agent Fluconazole (F421000).<br>References Richard, K. et al.: Antimicrob. Ag. Chemother., 27, 832 (1985); Yasohara, Y., et al.: PCT Int. Appl. WO 9528374 A1 19951026. Oct 26, 1995<br></p>

<p>Applications (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide is used as a reactant in the synthesis of ketolides methyloxoerythromycins with antibacterial activity as highly potent against macrolide-resistant and susceptible respiratory pathogens.<br>References Agouridas, C., et al.: J. Med. Chem., 41, 4080 (1998);<br></p>

<p>Applications Cyclopropylhydrazine Dihydrochloride, is a building block used in preparation of more complex compound.<br></p>

<p>Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).<br>References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Adams, M. et al.: Synth. Comm., 29, 2419 (1999); Foroumadi, A. et al.: Arch. Pharm. Res., 30, 138 (2007);<br></p>

<p>Applications Ethyl (Z)-3-(Dimethylcarbamoylamino)-4,4,4-trifluoro-but-2-enoate is an intermediate in the synthesis of Tiafenacil (T436300), which is a uracil herbicide used as a pesticide for the prevention and control of plants.<br>References Peng, X., et al. Faming Zhuanli Shenqing, 68pp Patent 2018 CODEN:CNXXEV<br></p>

<p>Applications 5-​Bromopentyl Acetate is used to model the toxicity of haloesters on marine bacterium such as Vibrio fischeri.<br>References Cornin, M.T.D, et. al.: SAR QSAR Environ. Res., 11, 301 (2000)<br></p>

<p>Stability Moisture Sensitive<br>Applications Oleyl Chloride is used as a chemical reagent in the preparation of Vitamin E analogs as well as antiviral nucleoside phosphoramidate prodrugs used in the treatment of HIV and HBV.<br>References Cho, J. et al.: Bioorg. Med. Chem., 22, 6665 (2014); Iwata, R. et al.: Bioorg. Med. CHem. Lett., 25, 815 (2015);<br></p>

<p>Applications TRIMETHYLSTEARYLAMMONIUM CHLORIDE (cas# 112-03-8) is a useful research chemical.<br></p>

<p>Applications 2,6-Dichlorobenzonitrile (DCBN or dichlobenil) is a herbicide and is slightly toxic for humans. It is metabolized in the liver by the enzyme CYP2A6.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, H., et al.: Soil Sci. Soc. Am. J., 67, 122 (2003); Shedletzky, E., et al.: Plant Physiol., 94, 980 (1990)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2,3-Dichloropropionyl Chloride is used as a reagent in the synthesis of 6-chloro-5-cyclohexyl-1-indancarboxylic acid, a potent analgesic, antipyretic, and antiinflammatory agent, and its related compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sawa, Y., et al.: Yakugaku Zasshi, 96, 653 (1976)<br></p>

<p>Applications 4-(4-Fluorophenyl)aniline<br></p>

<p>Applications 3-amino-5-chloro-1,3-dihydro-2H-indol-2-one hydrochloride (cas# 1104895-64-8) is a useful research chemical.<br></p>

<p>Applications Methyl 2-(4-Bromophenyl)-2,2-dimethylacetate (cas# 154825-97-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Azido-3-chloro-2-propanol, Technical Grade (cas# 51275-91-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Used for preparation of substituted thiazolesulfonamides as antiglaucoma agents.<br>References Boie, Y., et al.: Eur. J. Pharmacol., 340, 227 (1997), Boyer, F., et al.: J. Med. Chem., 43, 843 (2000), Lipinski, C., et al.: J. Pharmacol. Toxicol. Methods, 44, 235 (2000), Kimura, M., et al.: Endocrinology, 142, 4428 (2001),<br></p>

<p>Applications 1-(4-CHLOROPHENYL)CYCLOBUTANAMINE HYDROCHLORIDE (cas# 1228878-71-4) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-2-nitrobenzenediazonium Chloride is reduced in the presence of hypophosphorous acid and carbon powder resulting in functionalized carbon powder with chloronitrophenyl groups attached on carbon particle surface;Also, it is an intermediate used in the synthesis of 2,4-Di-tert-butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d20 (D428017), which is an isotope labelled form of 2,4-Di-tert-butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol (D428015), which is a UV absorber.<br>References Pandurangappa, M., et al.: J. Solid State Electrochem., 12, 1411-1419 (2008); Moisan, J.: Eur. Polymer J., 16, 979 (1980); Nakata, H., et al.: Environ. Sci. Technol.,43, 6920 (2009)<br></p>

<p>Applications It is useful in photochromic materials.<br></p>

<p>Applications 2-Fluoro-4-(methylsulfonyl)benzoic acid<br></p>

<p>Applications N-​Methylcyclopropanami​ne Hydrochloride can be used as reactant/reagent in preparation of substituted benzazinones as antibacterial compounds.<br>References Jin, Q., et al.: PCT Int. Appl., WO 2017098440 A1 20170615 (2017)<br></p>

<p>Applications 4-Bromo-3-fluoroaniline is an intermediate used for the synthetic preparation of Tradizolid and various pharmaceuticals such as the synthesis of several lateral difluoro-substituted 4,4"-dialkyl- and 4,4"-alkoxyalkylterphenyls.<br>References Gray. G., et al.: Molec. Crystals. Liquid. Crystals., 204, 43 (1991); Ng, B.H., et al.: J. Chem. Soc., 2815 (1958);<br></p>

<p>Applications 4-bromo-1,1-difluorobutane (cas# 1457946-33-6) is a useful research chemical.<br></p>

<p>Applications 1-azido-4-(bromomethyl)benzene (cas# 74489-49-9) is a useful research chemical.<br></p>

<p>Applications 6,7-Dichloro-1-tetralone (cas# 25095-57-2) is a useful research chemical.<br></p>

<p>Applications Hydroxocobalamin Hydrochloride acts as a spin trap for radical polymerization in water when reduced with ascorbic acid.<br>References Ng, Y., et al.: Macromol. Res., 20, 473-476 (2012)<br></p>

<p>Applications METHYL 2-HYDROXY-4-IODOBENZOATE (cas# 18179-39-0) is a useful research chemical.<br></p>

<p>Applications 1-Fluoro-4-iodobenzene<br></p>

<p>Applications 2-Bromothiophene (cas# 1003-09-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications O-(2-Bromo-6-chlorophenyl) O-Ethyl S-Propyl Phosphorothioate is a useful intermediate.<br></p>

<p>Applications Methyl-2-bromopentanoate is a reagent used in the synthesis of oxazepinones and substituted benzofurans<br>References Kowalewska, M. et al.: Tetragedron, 64, 5085 (2008); Kwiecien, H. et al.: Synth Comm., 37, 3599 (2007);<br></p>

<p>Applications A useful synthetic intermediate.<br></p>

<p>Applications 4-Chloro-2,6-difluorophenylboronic acid<br></p>

<p>Applications 4-Bromo-3,5-dimethoxybenzoic acid<br></p>

<p>Applications Bis(2-bromoethyl)selenium dibromide is reacted with pyridine to synthesize hypervalent T-shaped coordination compounds. Bis(2-bromoethyl)selenium dibromide is also used as a transfer reagent to carry out the one-step alkoxyselenation of cyclohexene.<br>References Miura, M., et al.: J. Chem. Soc. Perk. T 1, No vol. given, 1719 (1995); Takanohashi, Y., et al.: J. Chem. Soc. Perk. T 1, No vol. given, 813 (1993)<br></p>

<p>Applications 3-Chloro-5-hydroxymethylphenylboronic acid, pinacol ester<br></p>

<p>Applications 2,3-Dichloroquinoxaline is a dichlorinated quinoxaline derivative with antimicrobial activity. 2,3-Dichloroquinoxaline is used in the preparation of quinoxaline derivatives of cancer chemopreventive activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metzner, J. et al.: Pharmazie, 36, 368 (1981); Galal, S.A&gt; et al.: Eur. J. Med. Chem., 46, 327 (2011);<br></p>

<p>Applications 1-(Bromomethyl)-2-fluoro-4-(trifluoromethyl)benzene is used in the development of quinoline derivatives, a novel small molecule that inhibit NS5b polymerase, a key enzyme of the viral life-cycle.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kumar, D. V., et al.: Bioorg. Med. Chem. Lett., 21, 82-87 (2011)<br></p>

<p>Applications 1-Bromooctadecane is a reagent in the preparation of branched glycosyl phosphatidyl inositol (GPI) anchors of rat brain Thy-1.<br>References Pekari, K., et al.: J. Org. Chem., 68, 1295 (2003);<br></p>

<p>Applications Di-[2-(4-pyridyl)ethyl]sulfide Dihydrochloride is a compound useful in organic synthesis.<br></p>

<p>Applications (2-ethoxyethyl)hydrazine dihydrochloride (cas# 809282-62-0) is a useful research chemical.<br></p>

<p>Applications 21-Desacetoxy-21-Chloro Anecortave has been used in the preparation of pregnane derivatives.<br>References Hofmeister, H., et. al.: Ger. Offen., DE 3434448 A1 19860327 (1986)<br></p>

<p>Applications Ethyl (pentafluorobenzoyl)acetate (cas# 3516-87-8) is a useful research chemical.<br></p>