Organic Halides

Applications 4-Fluorobenzonitrile is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wan, J. et al.: Org. Lett., 15, 2742 (2013); Kormos, C. et al.: J. Med. Chem., 56, 4551 (2013);

Applications N-(2-Azidoethyl) Cyclen is used in the synthesis of lanthanide cyclen derivative complexes.
References Szijjarto, C., et al.: Dalton Trans., 41, 7660 (2012)

Applications 2-Bromo-1-(2-ethoxyphenyl)ethanone is used as a reagent in the preparation of aroylfurans and aroylthiophenes which are used in the treatment of neoplastic and autoimmune diseases.
References Eberle, M., et al.: Preparation of aroylfurans and aroylthiophenes for treating neoplastic and autoimmune diseases, WO Patent 2005061476, Jul 7, 2005;

Applications 1-Bromo-3,4-dichlorobenzene

Applications 3-Bromothioanisole (cas# 33733-73-2) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Bromo-1,4-dichlorobenzene is a reactant used in the synthesis of C-13 and C-14-labeled versions of the investigational proteasome inhibitor MLN9708.
References Plesescu, M., et. al.: J. Labelled Compd. Rad., 56, 464 (2013)

Applications 5-​Bromopentyl Acetate is used to model the toxicity of haloesters on marine bacterium such as Vibrio fischeri.
References Cornin, M.T.D, et. al.: SAR QSAR Environ. Res., 11, 301 (2000)

Applications Dibromoisocyanuric acid is a bromine compound with a superior bactericidal activity.
References Gottardi, W., et al.: J. Appl. Microbiol., 116, 1427 (2014)

Applications o-Chloramine T (cas# 110076-44-3) is a useful research chemical.

Applications 2-Amino-3-bromo-5-chlorobenzoic Acid is used as a starting material in the synthesis of a series of 3-(2-(2-methoxyphenyl)-2-oxoethyl) quinazolinone derivatives, which showed anticoccidial activity against Eimeria tenella in chicken.
References Ye, Changwen., et al.: Pestic. Biochem. Phys., 97(3), 194-198 (2010)

Applications 2-Fluoro-5-(trifluoromethyl)benzoic acid

Applications 4-(4-Chlorophenyl)but-3-en-2-one (cas# 3160-40-5) is a useful research chemical.

Applications 2,4-Dimethylbenzenesulfonyl Chloride is used as a reagent in the synthesis of dimethyl benzimidazolones as potent and selective inhibitors of BRPF1 bromodomain. 2,4-Dimethylbenzenesulfonyl Chloride is also used as a reagent in the synthesis of quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for the treatment of Gaucher disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Demont, E.H., et al.: ACS Med. Chem. Lett., 5, 1190 (2014); Marugan, J.J., et al.: J. Med. Chem., 54, 1033 (2011)

Stability Moisture Sensitive
Applications Chlorocarbonylsulfenyl chloride is a useful research chemical for organic synthesis and other chemical processes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sorra, K., et al.: Int. J. Mol. Sci., 15, 16500 (2014); Gurjar, A. S., et al.: Bioorg. Chem., 57, 90 (2014); Enache, L., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2005)

Stability Moisture Sensitive
Applications Trifluoromethanesulfonic Anhydride is a strong electrophile used in chemical synthesis for introducing the triflyl group.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cai, D. et al.: Org. Synth., 10, 112 (2004);

Applications 1-Bromo-2,3-dimethyl-2-butene is used as a reagent in the synthesis of (+)-virantmycin (CAS#: 104871-14-9).
References Morimoto, Y., et al.: Tetrahedron, 52, 10631 (1996)

Applications o-Iodochlorobenzene is a building block that has been used as a reactant for the synthesis of biaryl derivatives of seasamol used for their antioxidant activity against DPPH radical.
References Rodriguez, S.A., et. al.: Australian J. Chem., 66, 1334 (2013)

Stability Moisture Sensitive
Applications 2,3-Dichloropropionyl Chloride is used as a reagent in the synthesis of 6-chloro-5-cyclohexyl-1-indancarboxylic acid, a potent analgesic, antipyretic, and antiinflammatory agent, and its related compounds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sawa, Y., et al.: Yakugaku Zasshi, 96, 653 (1976)

Applications 1-[(6-aminohexyl)sulfanyl]ethan-1-one hydrochloride (cas# 98486-87-4) is a useful research chemical.

Applications 4-Bromocyclohexanone is an organic building block, used as a reactant in the preparation of alkylbenzenes via nickel-catalyzed cross-coupling with arylfluorosilanes.
References Powell, D., Fu, G.: J. Am. Chem. Soc., 126, 7788 (2004);

Applications 1-Bromo-2,3-dimethyl-benzene is a useful synthetic intermediate. It is used as a reagent to synthesize vaniprevir. It can also be used to synthesize various piperidine derivatives, e.g., 4-arylpiperidines and cinnamoylpiperidine, which are 5-HT2C agonist and PAR1 antagonist, respectively.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Song, Z., et a;.: J. Org. Chem., 76, 9553 (2011); Conway, R., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012); Planty, B., et al.: Bioorg. Med. Chem. Lett., 20, 1735 (2010)

Applications 2-[(Benzyloxycarbonyl)amino]-4,4,4-trifluorobutanoic acid is used in the preparation of benzamides and nicotinamides as spleen tyrosine kinase inhibitors.
References Jia, Z., et al.: PCT Int. Appl., 359 (2012)

Applications 4,4-diethylcyclohexan-1-amine hydrochloride (cas# 1087747-58-7) is a useful research chemical.

Applications 9-Fluorenemethanol is used in the design and in the synthesis of novel type somatostatin analogs with antiproliferative activities on A431 tumor cells.
References Miyazaki, A., et al.: Tetrahedron Lett., 45, 6323 (2004)

Applications 1-Bromo-4-ethylbenzene is organo bromide with flame retardant properties.
References Day, M. et al.: J. Fire Sci., 1, 255 (1983);

Applications [4-(Cyclopropylmethyl)phenyl]methanamine Hydrochloride is a useful research chemical for organic synthesis.

Applications 3-Bromo-4-isopropylbenzoic acid

Applications 1-Azido-3-chloro-2-propanol, Technical Grade (cas# 51275-91-3) is a compound useful in organic synthesis.

Applications Substrate specificity of haloalkane dehalogenases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),

Applications 2,6-Difluorobenzyl alcohol

Applications Used for preparation of substituted thiazolesulfonamides as antiglaucoma agents.
References Boie, Y., et al.: Eur. J. Pharmacol., 340, 227 (1997), Boyer, F., et al.: J. Med. Chem., 43, 843 (2000), Lipinski, C., et al.: J. Pharmacol. Toxicol. Methods, 44, 235 (2000), Kimura, M., et al.: Endocrinology, 142, 4428 (2001),

Applications N-(Bromomethyl)phthalimide (cas# 5332-26-3) is a useful research chemical.

Applications 1,1,1-Trifluoro-2-iodoethane (cas# 353-83-3) is a compound useful in organic synthesis.

Applications 6-chloro-2,4-dimethylnicotinonitrile (cas# 101251-72-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Bromo-6-chlorobenzoic acid is used in the syntheis of Diclofenac Monobromo Sodium Salt Impurity (D436490).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Moser, P., et al.: J. Med. Chem., 33, 2358 (1990),

Stability Store FROZEN
Applications Material that was assayed to be approximately 80% pure was diluted to 5% in benzene.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications O-((Perfluorophenyl)methyl)hydroxylamine Hydrochloride functions as one of the substances used in the identification of stable cytotoxic factors in extracts of cigarette smoke and in the pharmacological characterization of their cytotoxicity.
References Noya Y., et al.: Toxicology, 314, 1 (2013)

Applications Methyl 12-Aminododecanoate Hydrochloride (cas# 4271-86-7) is a compound useful in organic synthesis.

Applications 1-Chloro-4-(2,2,2-trichloroethyl)benzene is used as a compound to study effects such as singlet vs triplet reactivity of photogenerated α,n-didehydrotoluenes and as well, the polar effect in reactions with substituted benzyl radicals with carbon tetrachloride.
References Pedroli, C., et al.: J. Org. Chem., 82, 6592-6603 (2017); Dneprovskii, A.S., et al.: Russ. J. Organ. Chem., 35, 1495-98 (1999);

Applications 2,4-Dibromophenol Acetate (cas# 36914-79-1) is a compound useful in organic synthesis.

Applications [(1-Fluoroethenyl)sulfinyl]benzene is an intermediate used in the synthesis of 13-Fluorodibenzo[a,i]pyrene (F588440), which is a polycyclic aromatic hydrocarbon (PAH) thus potentially exhibiting carcinogenic properties through activation of P450 mono-oxygenase enzymes. Also, it has unique electrical and optical properties due to being a conjugated macromolecule.
References Zhang, F. et al.: J. Org. Chem., 65, 3952 (2000); Amaladass, P. et al.: Tetra., 64, 7992 (2008);

Applications 2-[(4-fluorobenzyl)amino]ethanol (cas# 22116-33-2) is a useful research chemical.

Applications It is useful in photochromic materials.

Applications Chlorsulfaquinoxaline is used to prepare carbonic anhydrase inhibitors 1,3,4-thiadiazole-2-sulfonamide derivatives as antitumor agents.
References Supuran, C., et al.: Eur. J. Med. Chem., 35, 867 (2000)

Applications 4-Iodophenol is used in chemiluminescence imaging assays and experiments, as diagnostic agents in order to detect cancer cells in patients. Also it is used in the synthesis of agonists towards the estrogen β receptor.
References Bi, S. et al.: Chem. Comm., 49, 3452 (2013); Demkowicz, S. et al.: RSC, Adv., 3, 3697 (2013);

Applications 2-Ethoxy-N,N,N-trimethylethanaminium chloride is being used for the study of antigibberellin activity and the role quaternary ammonium salts play.
References Gafurov, R.G., et al.: Doklady Biological Sciences, 394, 66-70 (2004); Gafurov, R.G., et al.: Doklady Biological Sciences, 421 (2004);

Applications 2-Fluoro-4-(methylsulfonyl)benzoic acid

Applications 4-Trifluoromethoxybenzyl Bromide is a useful synthetic intermediate. It is used to prepare (nitro)[(trifluoromethoxy)benzyloxy]dihydroimidazo[2,1-b][1,3]oxazines with antitubercular activities. It is also used to synthesize tetrahydronaphthalenols with anti-allergic activities.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, X., et al.: Bioorg. Med. Chem. Lett., 18, 2256 (2008); Barlow, J., et al.: Eur. J. Med. Chem., 46, 1545 (2011)

Applications 2-Amino-4-(trifluoromethyl)benzenethiol Hydrochloride can be used as reactant/reagent in preparation of fused benzo-diazepinones/oxazocinone/thiazapines/diazapines/diazocins/thiazine/indoles via CuI-L-proline catalyzed SN2 reaction.
References Srinivasulu, V., et al.: Tetrahedron, 73, 2139 (2017)

Applications 6-Fluoronicotinic acid

Applications Methyl 2-chloro-6-nitrobenzoate

Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.
References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)

Impurity Budesonide EP Impurity J
Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.
References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)

Stability Very Very Moisture Sensitive
Applications Difluoromethanesulfonyl Chloride is a reactant used in the synthesis of ketoconazole sulfonamide analogs as antifungal agents.
References Blass, B. et al.: Bioorg. Med Chem. Lett., 26, 5825 (2016);

Applications 1,3,5-Tribromobenzene, is a reagent that can be used in the preparation of different inhibitors. It is also a substituted Bromobenzene, a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.
References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);

Applications A derivative of dioxane.

Stability Air Sensitive
Applications 4-IODO-2-NITROANILINE (cas# 20691-72-9) is a useful research chemical.

Stability Moisture Sensitive
Applications Di-tert-butyl chloromethyl phosphate (cas# 229625-50-7) is a useful research chemical.

Applications 1-(4-Bromophenyl)ethane-1,2-diol is used as a reactant in the regioselective palladium-catalyzed O,S rearrangement of cyclic thiocarbonates.
References Mahy, William, et al.: Euro. J. of Org. Chem., 2017(43), 6441-6444 (2017)

Applications Amino(3-​chlorophenyl)​acetic Acid functions as intermediate useful in the preparation of synthetic penicillins, also used in the structure-activity relationship examination of several drugs containing the benzyl moiety, their roles in biochemical and pharmacological processes.
References Hansch, C., et al.: J. Med. Chem., 13, 957 (1970); Holdrege, C. T., et al.: Can. (1975), CA 966853 A2 19750429;

Applications 7-Chloro-4-oxo-4H-chromene-2-carboxylic acid (cas# 114741-22-9) is a useful research chemical.

Applications Methyl 5-cyano-2-fluorobenzoate