Organic Halides

<p>Applications 1H,1H,2H,2H-Perfluorohexyl iodide has been used for the study for fluorinated phosphonium ionic liquids as a reagent, and in general is used as a reactant in organic reactions.<br>References Rauber. D., et al.: Phys. Chem. Chem. Phys., 19, 27251-58 (2017); Hawker,R.R., et al.: ChemComm., 54, 2296-99 (2018);<br></p>

<p>Applications (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.<br>References Wang, X., et al.: Org. Lett., 16, 4090 (2014);<br></p>

<p>Applications 2-Amino-3,5-dibromobenzoic acid (cas# 609-85-8) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-1,1’-biphenyl (cas# 2051-62-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Glycerol kinase substrate specificity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Castro, C., et al.: Biochemistry, 7, 3213 (1968), Janssen, D., et al.: Eur. J. Biochem., 171, 67 (1988), Kurihara, T., et al.: J. Biochem., 117, 1317 (1995),<br></p>

<p>Applications Di-β,β'-Chloroethylphosphoric Acid, is a dialkyl hydrogen phosphates, that can undergo the electrophilic trifluor- omethylation to produce trifluoromethyl phosphates in order to increase the lipophilicity of functional groups.<br>References Santschi, N., et al.: J. Fluorine Chem., 135, 83 (2012);<br></p>

<p>Stability Light Sensitive<br>Applications Dibromoacetonitrile is a carcinogenic nitrogenous disinfection byproduct. Dibromoacetonitrile in drinking water was linked to oral cavity cancer in rats and forestomach cancer in mice. In addition, Dibromoacetonitrile may cause oxidative damage in rat brain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, Z., et al.: Chem. Eng. J. 306, 1180 (2016); Krasner, S. W., et al.: Environ. Sci. Technol. 50, 9583 (2016); Natl Toxicol Program Tech Rep Ser. 544, 1 (2010); Klattisaksiri, P., et al.: Water Res 98, 160 (2016); Sayed, R. H., et al.: Environ Toxicol Pharmacol. 34, 849 (2012)<br></p>

<p>Applications Chlorprothixene<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3,3-Difluoroazetidine Hydrochloride is used in preparation of Dihydropyrimidine compounds as antiviral agents.<br>References Song, H., et al.:U.S. Pat. Appl. Publ., (2020);<br></p>

<p>Stability Very Hygroscopic<br>Applications (S)-Isopropyl-2-aminopropanoate Hydrochloride, is a chemical reagent used in the synthesis of anti-HCV prodrugs based on imidazotriazine and pyrrolotriazine molecules.<br>References Tyndall, E. Bioorg. Med. Chem. Lett., 25, 869 (2015);<br></p>

<p>Applications N,N-Dimethyl-3-phenylpentan-3-amine Hydrochloride is a useful research chemical.<br></p>

<p>Stability Very Moisture Sensitive<br>Applications Chlorotriphenylstannane is used in the synthesis of nanoparticles which bear triamide ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shariatinia, Z. et al.: Beil. J. Nanotech., 4, 94 (2013);<br></p>

<p>Applications Ethyl hydrazinoacetate, HCl<br></p>

<p>Applications N-[(4-chlorophenyl)methyl]cyclopentanamine is a useful reagent for the preparation of γ-​lactams.<br>References Fujii, T., et al.: Tetrahedron Letters, 61, 152276 (2020)<br></p>

<p>Applications 3-Chlorodiphenylamine (cas# 101-17-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,3,4-Trichlorophenylboronic acid (cas# 352530-21-3) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications p-(2-Bromo)vinyl Anisole (cas# 6303-59-9) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4,5-Dichlorophthalic anhydride<br></p>

<p>Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethylamine Hydrochloride a chemical used in various chemical organic syntheses and biological studies.<br>References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010);<br></p>

<p>Applications 4-Chlorobenzenesulfonic acid is an aromatic compound that is used to synthesize a variety of sulfonyl azides. 4-Chlorobenzenesulfonic acid is also used for its effectivenes in promoting para-selective reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bovonsombat, P., et al.: Tetrahedron, 66, 6928 (2010); Kiani, A., et al.: J. Sulf. Chem., 35, 119 (2014)<br></p>

<p>Applications 4,4,5,5,6,6,7,7,7-nonafluoroheptan-1-ol (cas# 83310-97-8) is a useful research chemical.<br></p>

<p>Applications 1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist.<br>References Kakasaheb, N. et al.: Int. J. Pharm. Sci., 6, 370 (2014); Mao, Y. et al.: Heterocycles, 81, 1503 (2010);<br></p>

<p>Applications 1,3-Dichloro-5,5-dimethylhydantoin is used as a reagent in the synthesis of macrolactonolides which can be used as potential antiinflammatory drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tomaskovic, L., et al.: Bioorg. Med. Chem., 21, 321 (2013)<br></p>

<p>Applications 4-Aminomethyl Benzamidine Dihydrochloride is a small molecule CXCR4 antagonist.<br>References Zhan, Weiqiang, et al.: J. of Med. Chem., 50(23), 5655-5664 (2007)<br></p>

<p>Applications Tryptamine hydrochloride (cas# 343-94-2) is a useful research chemical.<br></p>

<p>Applications 1-phenyl-2-(propylamino)-1-Butanone Hydrochloride is a α-Aminoketone derivatives and a useful building block.<br>References Koeppe, H.; et al.: DE 1493461 (1972).<br></p>

<p>Applications Propacetamol HCl (cas# 66532-86-3) is a useful research chemical.<br></p>

<p>Applications 2-[(Chloroacetyl)amino]benzoic Acid is used to prepare (thiazolyl)arylquinazolinone derivatives via cyclocondensation.<br>References Giri, R., et al.: Eur. J. Med. Chem., 44, 2184 (2009);<br></p>

<p>Applications An intermediate of racemic Atomoxetine.<br>References Hage, A., et al.: Biotechnol. Bioeng., 73, 69 (2001), La Regina, G., et al.: J. Med., Chem., 51, 3841 (2008),<br></p>

<p>Applications 2,6-Difluorobenzoylacetonitrile is used in the synthesis of thienodiazepinones which can have poor central nervous system depressant activity.<br>References Binder, D., et al.: Arch. Pharm., 313, 587 (1980)<br></p>

<p>Applications 1,2-Dichloroethane is one of the major waste products of the Vinyl Chloride industries, and has also been classified as a potential human carcinogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hung, W., et al.: Appl. Surf. Sci., 255, 2205 (2008); Rannug, U., et al.: Chem.-Biol. Int., 20, 1 (1978)<br></p>

<p>Applications 1-(Bromomethyl)pyrene (cas# 2595-90-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Bromo-3-chloropropane can be used safer and equally efficient alternative to chloroform as a phase-separation agent in the 1-step method of RNA isolation from biological samples such as animal and plant tissue.<br>References Chomczynski, P. et al.: Anal. Biochem., 225, 163 (1995); Chey, S. et al.: Anal. Biochem., 411, 164 (2011);<br></p>

<p>Stability Hygroscopic<br>Applications Heptafluorobutyric Acid (HFBA) is used in reversed-phase chromatography.<br> E0<br>References Satake, I., et al.: Biopolymers, 15, 2263 (1976), Aso, K., et al.: Biosci. Biotech. Biochem., 56, 755 (1992), Cecchi, T., et al.: J. Chromatogr., 1216, 1789 (2009),<br></p>

<p>Applications Dichlorobenzenamine is used in the synthesis of effective inhibitors of plant δ1-pyrroline-4-carboxylate reductase. Also used in the preparation of anti-tumor agents based upon diaryl urea derivatives.<br>References Forlani, G. et al.: J. Agri. Food Chem., 61, 6792 (2013); Zhai, X. et al.: Molecules, 18, 2904 (2013);<br></p>

<p>Applications Used for preparation of an inhibitor of the NLS-derived BC peptides.<br>References Byk, G., et al.: J. Med. Chem., 39, 3174 (1996), Gallay, P., et al.: J. Virol., 70, 1027 (1996), Nigg, E., et al.: Nature, 386, 779 (1997), Friedler, A., et al.: Biochemistry, 37, 5616 (1998),<br></p>

<p>Applications 11-Bromoundecanenitrile is an intermediate in synthesizing N-(12-Aminododecyl)deoxynojirimycin (A608080), which is used in the preparation of imino-alditols as glycosidase inhibitors.<br>References Jefferies, I., et al.: Bioorg. Med. Chem. Lett., 7, 1171 (1997); Hassan, A., et al.: Carbohydr. Res., 339, 1565 (2004); Lundt, et al.: Bioorg. Med. Chem., 14, 1737 (2006);<br></p>

<p>Applications 2,2-Difluoro-3-hydroxy-(3-pyridyl)propionic Acid (cas# 887354-54-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 3-Bromopyruvate is used in the preparation of 1,2,4-trisubstituted imidazoles as inhibitors of growth factor-β type I ALK5 inhibitors.<br>References Guo, C. et al.: Bioorg. Med. Chem. Lett., 23, 5850 (2013); Catarzi, D. et al.: Farmaco, 48, 447 (1993);<br></p>

<p>Applications Trichloroethylene is a common industrial solvent that is used in dry cleaning and metal degreasing. Trichloroethylene is also a suspected carcinogen to humans, and is a common groundwater contaminant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Little, D., et al., Appl. Env. Microb., 54, 951 (1988); Vogel, T. &amp; McCarty, P.: Appl. Environ. Microb., 49, 1080 (1985); Wartenberg, D., et al.: Environ. Health Persp., 108, 161 (2000)<br></p>

<p>Applications A chemical additive to control bacterial contamination in ethanol fermentation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vaisanen, O., et al.: J. Ind. Microbio., 4, 419 (1989), Costerton, J., et al.: J. Bacteriol., 176, 2137 (1994), Pirttijarvi, T., et al.: J. Appl. Bacteriol., 81, 445 (1996),<br></p>

<p>Applications A mixture of erythro and threo.<br></p>

<p>Applications 1,2,3-Tribromobenzene is an organic chemical reagent used in the synthesis of cis-trikentrin B as well as in the synthesis of diphenyl ethers for induction of CYP1A via the receptor mediated pathway.<br>References Chen, G. et al.: Env. Sci. Tech., 35, 3749 (2001); Chandrasoma, N. et al.: Tetra. Lett., 54, 913 (2013);<br></p>

<p>Applications 2,4,6-Tribromophenol a reagent used in industrial synthesis of compounds and pharmaceuticals. It is used in the synthesis of anti-HIV candidates. Identified as a metabolic impurity of industrial chemical runoff in humans and wildlife.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ludovici, D. et al.: Bioorg. Med. Chem. Lett., 11, 2229, (2001); Hovander, L. et al.: Arch. Env. Cont. Toxicol., 42, 105 (2002);<br></p>

<p>Applications 1-Chloro-4-(chlorophenylmethyl)benzene is used in the synthesis of novel benzhydrylpiperazine derivatives as cytotoxic compounds in the treatment of various cancers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gurdal, E. et al.: Drug Res., 63, 121 (2013); Yarim, M. et al.: Int. J. Mol. Sci., 13, 8071 (2013);<br></p>