Organic Halides

Applications 4-Fluoro-2-formylphenylboronic acid

Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.

Applications N-Phenyl 2-Bromo-5-Fluorobenzamide (cas# 949443-48-5) is a useful research chemical.

Applications 1,2,3,4-tetrachlorocyclopenta-1,3-diene (cas# 695-77-2) is a useful research chemical.

Applications 6-Chloro-7-deazaguanine (cas# 84955-31-7) is a compound useful in organic synthesis.

Applications Tetrabutylammonium tetrafluoroborate (cas# 429-42-5) is a useful research chemical.

Applications 1,3-Difluoro-2-propanol is the major ingredient of Gliftor (G410000), a rodenticide. 1,3-Difluoro-2-propanol was also used in the synthesis of 1,3-difluoroacetone.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Menon, K., et al.: J. Biochem. Mol. Toxicol., 15, 47 (2001); Xie, W., et al.: J. Hygiene Res. 31, 316 (2002); Menon, K., et al.: J. Biochem. Mol. Toxicol., 15, 47 (2001)

Stability Moisture Sensitive, Toxic
Applications Benzyl Chloromethyl Ether is a reagent in the preparation of benzoyl-hydroxypyrimidine-diones, which are dual inhibitors of HIV reverse transcriptase and integrase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tang, J., et al.: Bioorg. Med. Chem. Lett., 21, 2400 (2011); Berkley, S., et al.; Nat. Med. 16, 981 (2010)

Applications 4-Nitrobenzyl Bromide is used in the synthesis of di and tri-substituted azoles. Also used in the preparation of N6-Benzyladenosine-5’-uronamides as selective A3 adenosine agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gallo-Rodriguez, C. et al.: J. Med. Chem., 37, 636 (1994); Appukkuttan, P. et al.: Org. Lett., 6, 23 (4223);

Applications (1R)-4-Bromo-2,3-dihydro-1H-inden-1-amine is used to prepare sphingosine 1 phosphate receptor modulators useful in treatment of S1P1-associated diseases.
References Boehm, M., et al.: PCT Int. Appl., WO 2012158550 A2 20121122 (2012)

Applications 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol is a polyethylene glycol used in the synthesis of novel glycolipids that bind HIV-1 cell surface glycoprotein Gp120 with potential application to pharmaceutical HIV-1 drugs. Also used in the synthesis of PET imaging agents targeting brain β-amyloid.
References LaBell, R. et al.: Bioconj. Chem., 13, 143 (2002); Zhang, W. et al.: Nucl. Med. Biol., 32, 799 (2005);

Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxopropanamide (cas# 87310-69-8) is a compound useful in organic synthesis.

Applications Ethyl Succinoyl Chloride, used in the synthesis of bivalent ligands for D2/D3 dopamine receptors. Also used in the preparation of antimicrobial pyrrolo-isoquinolinones.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gogoi, S. et al.: ACS Med. Chem. Lett., 3, 991 (2012);

Applications 2,4-Dichloro-3-Nitrobenzotrifluoride is a useful reagent in the preparation of aryl ethers as HIF-2α inhibitors used in the treatment of cancers.
References Dixon, D. D., et al.: From PCT Int. Appl. (2015), WO 2015035223 A1 20150312

Applications 1,3-Dibenzyl-5-fluorouracil (cas# 75500-02-6) is a compound useful in organic synthesis.

Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.

Applications Bis[2-(2-chloroethoxy)ethyl] Ether, is an impurity in the synthesis of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (C365875), which is a polyethylene glycol used in the synthesis of novel glycolipids that bind HIV-1 cell surface glycoprotein Gp120 with potential application to pharmaceutical HIV-1 drugs. Also used in the synthesis of PET imaging agents targeting brain β-amyloid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References LaBell, R. et al.: Bioconj. Chem., 13, 143 (2002); Zhang, W. et al.: Nucl. Med. Biol., 32, 799 (2005);

Applications 3-Bromo-benzenebutanoic Acid is a reactant used in the preparation of pyrrolo-(di)-benzazocinones via an intramolecular cyclization of N-acyliminium ions formed from 4,4-diethyoxybutyl amides (Erratum)
References King, F.D., et al.: Org. Biomol. Chem., 7, 5271 (2009); King, F.D., et al.: Org. Biomol. Chem., 7, 167 (2009)

Applications Methyl adipoyl chloride is a reagent that is used for improved heme-mimetics based on BAY 58-2667 (cinaciguat) and their effects on soluble guanylyl cyclase (sGC) activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References von Wantoch Rekowski, M., et al.: J. Med. Chem., 56, 8948 (2013);

Applications Thallium(I) trifluoromethanesulfonate is an used as a reagent in inorganic synthesis such as transition metal catalysts for intramolecular hydroamination of alkynes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mueller, T. E., et al.: Organometallics, 19, 170 (2000);

Applications Chlorocyclohexane, is a building block used in various chemical synthesis.

Applications 4-{[(p-Fluorophenyl)imino]methyl}phenol is used in the preparation of benzylacetones which promote anti-fungal activity.
References Sandhar, R. et al.: J. Ind. Council Chem., 22, 32 (2005);

Applications 4-(Dimethylphosphinyl)benzenamine Hydrochloride is the salt form of 4-(Dimethylphosphinyl)benzenamine, a reactant in the preparation of 9-(arenethenyl)purines as dual Src/Abl kinase inhibitors.
References Huang, Wei-Sheng, et al.: J. of Med. Chem., 52(15), 4743-4756 (2009)

Applications 4-Fluoro-1,2-phenylenediamine has shown anticancer activity in human prostate adenocarcinoma cell.
References Ahmed, H.A.: Bull. Faculty Pharmacy, 49, 25 (2011)

Stability Moisture Sensitive
Applications 1,5-Dichlorohexamethyltrisiloxane is a useful chemical in organic synthesis.
E0
References Tagne Kuate, Alain C., et al.: J. of Organometallic Chem., 751, 628-637 (2014);Basenko, S. V., et al.: Doklady Chem., 450(1), 135-138 (2013);Gao, Fei, et al.: Polymer Journal, 43(2), 136-140 (2011)

Applications 2-((3-Chloro-2-formylphenyl)thio)acetic Acid is a useful research chemical.