Organic Halides

Applications (2-Chloro-4-cyanophenyl)boronic Acid is an intermediate used to prepare fused imidazole derivatives as TTK kinase inhibitors. It is also used in the synthesis of pyrimidothiophenes as HSP90 inhibitors.
References Kusakabe, K., et al.: PCT Int. Appl., WO 2011013729 A1 20110203 (2011); Dymock, B., et al.: PCT Int. Appl., WO 2005021552 A1 20050310 (2005)

Applications 2-Chloro-5-Fluoro-3-(Trifluoromethyl)Benzoic Acid (cas# 1805955-65-0) is a useful research chemical.

Stability Moisture Sensitive
Applications BROMO-PEG3-BROMIDE (cas# 31255-10-4) is a useful research chemical.

Applications 2-Bromobutane is used in the various organic synthesis, existing as a grignard reagent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Girard, P. et al.: J. Am. Chem. Soc., 102, 2693 (1980); Apsel, B. et al.: Nat. Chem. Biol., 4, 691 (2008);

Applications 1,3-Diiodobenzene is a common chemical reagent used in the synthesis of multinuclear complexes of large porphyrinoids. Also used in the synthesis of small molecular probes as sensors with low viscosity values.
References Miguel, D. et al.: Org. Lett., 17, 2844 (2015);

Applications Methyl 5-chlorothiophene-2-carboxylate (cas# 35475-03-7) is a useful research chemical.

Applications 3-(Methylamino)-1-phenylpropan-1-one hydrochloride (cas# 2538-50-3) is a useful research chemical.

Applications Hydrobromide salt of Triphenylphosphine, used in the preparation of uridine derivatives as substrate donor analogs of UDP-sugars for glycosyltransferases. Also used in the preparation of tensioactive and antibacterial deoxyglycoside compounds via catalysis.
References Wandzik, I. et al.: Bioorg. Chem., 37, 211 (2009); Martins, A. et al.: Eur. J. Org. Chem., 2014, 1448, 2013

Applications (1S,3R)-3-(4-Bromophenyl)cyclopentanamine is a stereoisomer of (1R,3S)-3-(4-Bromophenyl)cyclopentanamine, used in the synthesis of pharmaceutical agents.

Applications methyl amino(2-bromophenyl)acetate hydrochloride (cas# 1219408-44-2) is a useful research chemical.

Applications 2-Bromo-1-(4-dimethylaminophenyl)ethanone

Applications Ethenesulfonyl chloride is a useful reactant for the preparation of oral quinoline-based ALDH1A1 inhibitors as potential antitumor agents.
References Yang, SM., et al.: J. Med. Chem., 61, 4883-4903 (2018);

Applications 2-Bromo-1,4-dichlorobenzene is a reactant used in the synthesis of C-13 and C-14-labeled versions of the investigational proteasome inhibitor MLN9708.
References Plesescu, M., et. al.: J. Labelled Compd. Rad., 56, 464 (2013)

Applications Dibromoisocyanuric acid is a bromine compound with a superior bactericidal activity.
References Gottardi, W., et al.: J. Appl. Microbiol., 116, 1427 (2014)

Stability Moisture Sensitive
Applications Oleyl Chloride is used as a chemical reagent in the preparation of Vitamin E analogs as well as antiviral nucleoside phosphoramidate prodrugs used in the treatment of HIV and HBV.
References Cho, J. et al.: Bioorg. Med. Chem., 22, 6665 (2014); Iwata, R. et al.: Bioorg. Med. CHem. Lett., 25, 815 (2015);

Applications 4-(4-Chlorophenyl)but-3-en-2-one (cas# 3160-40-5) is a useful research chemical.

Applications 3-Bromoanisole is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.
References Hura, N., et al.: ACS Omega, 3, 1955 (2018); Srinivas L. K., et al.: Bioorg. Med. Chem. Lett., 28, 778 (2018); Yoon, D., et al.: ACS Med. Chem. Letters, 8, 1336 (2017)

Applications 1-Bromo-2,3-dimethyl-benzene is a useful synthetic intermediate. It is used as a reagent to synthesize vaniprevir. It can also be used to synthesize various piperidine derivatives, e.g., 4-arylpiperidines and cinnamoylpiperidine, which are 5-HT2C agonist and PAR1 antagonist, respectively.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Song, Z., et a;.: J. Org. Chem., 76, 9553 (2011); Conway, R., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012); Planty, B., et al.: Bioorg. Med. Chem. Lett., 20, 1735 (2010)

Applications 2-[(Benzyloxycarbonyl)amino]-4,4,4-trifluorobutanoic acid is used in the preparation of benzamides and nicotinamides as spleen tyrosine kinase inhibitors.
References Jia, Z., et al.: PCT Int. Appl., 359 (2012)

Applications Reagent used in the preparation of fluorescent dyes and indicators.
References Link, J., et al.: J. Med. Chem., 48, 5295 (2005), Martin, V., et al.: Bioorg. Med. Chem. Lett., 15, 1851 (2005),

Stability Hygroscopic
Applications (2R)-Tetrahydro-2-furanmethanamine is a stereoisomer of Tetrahydro-2-furanmethanamine (T293545) which is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Tetrahydro-2-furanmethanamine (T293545) is also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
References Lopez-Rodriguez, M. et al.: 44, 4504 (2001); Liu, G. et al.: J. Med. Chem., 50, 3086 (2007);

Applications 2,6-Diiodobenzene-1,4-diol is a metabolite of the antithyroid compound, Diacetyl-2,6-diiodoohydroquinone.
References Serif, George S., et al.: Biochem. Pharma., 12(8), 885-91 (1963)

Applications [4-(Cyclopropylmethyl)phenyl]methanamine Hydrochloride is a useful research chemical for organic synthesis.

Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)

Applications N-(Bromomethyl)phthalimide (cas# 5332-26-3) is a useful research chemical.

Applications 2-Bromo-6-chlorobenzoic acid is used in the syntheis of Diclofenac Monobromo Sodium Salt Impurity (D436490).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Moser, P., et al.: J. Med. Chem., 33, 2358 (1990),

Applications 3-Bromopentane-2,4-dione (cas# 3043-28-5) is a useful research chemical.

Applications 2-(azidomethyl)-1,3-difluorobenzene (cas# 106308-60-5) is a useful research chemical.