Organic Halides

<p>2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide is a carboxamide analog of dibucaine. It is synthesized from chloroacetyl chloride and isatin in the presence of sodium hydroxide. The synthesis has been scaled to an industrial level. 2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide has been shown to have analgesic properties, similar to those of dibucaine. Radiolysis of this compound gives a carboxylic acid and a heterocyclic ring product.</p>

<p>Desmethyl cyclobenzaprine hydrochloride is a metabolite of cyclobenzaprine, a drug used for the treatment of muscle spasms. Desmethyl cyclobenzaprine hydrochloride has been shown to have an increased potency for the termination of nerve impulses. These results were determined by in vivo studies using an assay on rat sciatic nerve and a study on human adrenergic receptors. This metabolite also shows potentiation effects with other drugs such as clonidine and prazosin, which are used to treat hypertension and anxiety, respectively. However, clinical relevance is still unknown due to the lack of data on desmethyl cyclobenzaprine hydrochloride's uptake and enhancement in humans.</p>

<p>Please enquire for more information about VIP Receptor-Binding Inhibitor L-8-K trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethyl 2-(chlorosulfonyl)acetate is a drug candidate that inhibits the enzyme cholesterol acyltransferase (ACAT), which is responsible for the formation of cholesterol esters. It has been shown to be effective in animal models for the treatment of metabolic disorders, such as hypercholesterolemia and hypertriglyceridemia. In addition, it has been shown to inhibit the activity of serine proteases, which are involved in coagulation, amido hydrolase, and nucleophilic attack reactions. Ethyl 2-(chlorosulfonyl)acetate has also been shown to activate gene product in cellular studies with mouse fibroblasts.</p>

<p>Please enquire for more information about DABCYL-gamma-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 2-(2-chloroethoxy)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Leu-Glu-His-Asp-chloromethylketone is a creatine kinase inhibitor that prevents the conversion of ATP to ADP. It inhibits mitochondrial pathways, leading to apoptotic and proapoptotic effects. Ac-Leu-Glu-His-Asp-chloromethylketone also has a kinetic effect on cells, where it causes necrotic cell death. This compound can cause proteolytic activity, which leads to the activation of caspase 9 and matrix metalloproteinases. Ac-Leu-Glu-His-Asp chloromethylketone has been shown to have antiinflammatory properties in cellular assays, as well as an ability to inhibit the synthesis of cellular proteins.</p>

<p>Please enquire for more information about Biotinyl-Hepcidin-25 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,4-Dibromobenzoic acid ethyl ester is a high quality reagent that can be used as an intermediate for the synthesis of complex compounds. It is also useful as a building block for the synthesis of speciality chemicals and research chemicals. 3,4-Dibromobenzoic acid ethyl ester can be used in reactions such as Friedel-Crafts reactions, reducing reactions, and condensations. This chemical is a versatile building block that can be used to construct organic molecules with diverse structures. 3,4-Dibromobenzoic acid ethyl ester is a fine chemical with CAS number 60469-88-7.</p>

<p>2-Bromoethane-1-thiol (2BET) is a hydrogen bond sensitive sensor that can be used in the detection of reactive oxygen species. 2BET has been shown to have a high sensitivity and selectivity to hydrogen peroxide, with an observed response time of less than 1 second. This sensor has been found to be useful for detecting short-term changes in hydrogen peroxide concentrations and can also detect long term changes due to its stability in the membrane. 2BET is also highly selective for hydrogen peroxide and does not react with other compounds, such as nitric oxide or sulfur dioxide. 2BET is a cavity type sensor that consists of two gold electrodes with a polyelectrolyte membrane between them. When exposed to reactive oxygen species, the polyelectrolyte membrane becomes crosslinked and this change in permeability can be detected by measuring the current across the electrodes. 2BET sensors are able to distinguish between isotopomers</p>

<p>Please enquire for more information about (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Chloro-2-nitrobenzaldehyde is a reactive intermediate that has been used to investigate the reaction mechanism of protonation. It is an n-oxide and has been shown to react with calcium carbonate under acidic conditions, forming a stable product. 4-Chloro-2-nitrobenzaldehyde has also been used in the synthesis of amides and nitro compounds. This compound possesses two functional groups, which are a nitro group and a chloro group on the aromatic ring.</p>

<p>CART (55-102) is a specific amino acid that has been shown to bind to the CART receptor. It has been found in human and rat tissue, including the brain, pituitary gland, and pancreas. This compound is thought to be involved in regulating appetite and energy expenditure. The CART (55-102) trifluoroacetate salt has been shown to be active in a variety of animal models for obesity and diabetes, as well as for reducing food intake.</p>

<p>Please enquire for more information about 8-Chloroimidazo[1,2-a]pyrazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The compound H-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-OH trifluoroacetate salt is a synthetic antigen for use in the production of immunoadsorbent conjugates. It is a postulated fluorescence molecule that interacts with specific antibodies to form an antigen. This antigen can be used as a probe for detecting antibodies in biological fluids and tissues by fluorescence microscopy and has been shown to have no antigenicity in skin reactions.</p>

<p>Please enquire for more information about 6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-(4-Chlorophenyl)-2-cyanoacetamide is a pyridine compound that can be synthesized from chloroacetonitrile and acetamide. It has been shown to react with an active methylene group in benzene or pyridine to produce a heterocycle. This reaction is reversible and can be used as a preparative method for the synthesis of heterocycles. The 1,3-dipolar cycloaddition of N-(4-chlorophenyl)-2-cyanoacetamide with nitro groups in nitrobenzene produces the corresponding 2-nitropyridines, which are important intermediates in the synthesis of other heterocycles. N-(4-Chlorophenyl)-2-cyanoacetamide has been used as an efficient method for the preparation of nitrogen nucleophiles that are useful for catalysis.</p>

<p>Please enquire for more information about H-Lys-Ala-AMC hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,9-Dimethyl-methylene blue zinc chloride double salt is a fluorescent dye that has been used in the study of hyaluronic acid and mesenchymal stem cells. The compound absorbs light at a wavelength of 580 nm, which is the same as the absorption wavelength for hyaluronic acid and mesenchymal stem cells. 1,9-Dimethyl-methylene blue zinc chloride double salt can be used to measure the amount of these compounds in tissues. This dye also shows sensitivity to artifacts such as hemolysis and lipemia, making it useful for research purposes.</p>

<p>Please enquire for more information about (R)-2-Methylmorpholine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-[2-Trifluoroethoxyphenoxy]ethyl methanesulfonate is a research chemical that is commonly used in the synthesis of enantioselective compounds. It has been clinically studied for its potential use in the treatment of prostatic hyperplasia, a condition characterized by an enlargement of the prostate gland. This compound has shown promising results in inhibiting the growth of prostatic cells and reducing symptoms associated with hyperplasia. Its enantioselective properties make it an ideal candidate for targeted therapy, allowing for more precise and effective treatment options. Researchers continue to explore the potential applications of 2-[2-Trifluoroethoxyphenoxy]ethyl methanesulfonate in various fields, including medicine and pharmaceuticals.</p>

<p>Please enquire for more information about (D-Lys6)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Arg-4MbetaNA hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fibrinopeptide B is a fibrinogen-derived peptide that has shown to inhibit the growth of HL-60 cells. It may be active as a receptor antagonist for thrombin and caproic acid. Fibrinopeptide B also inhibits angiogenesis by inhibiting the binding of acidic, basic proteins to the vascular endothelium in atherosclerotic lesions. The biological sample can be obtained from human serum or plasma.</p>

<p>Retrocyclin-1 trifluoroacetate salt is a synthetic antimicrobial peptide, which is derived from humanized sequences based on the theta-defensin family, originally found in certain primates. Retrocyclin-1 is particularly notable for its circular structure which contributes to its stability and biological activity. The peptide is produced through a process of solid-phase peptide synthesis, designed to mimic the native cyclic conformation of natural theta-defensins.</p>

<p>Nalpha-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide is a chemical compound that inhibits the activity of proteases. It has been shown to inhibit leukemia cells and actinomycetes. This chemical binds to the active site of proteases, inhibiting the hydrolysis of peptides by blocking the access of water molecules to the reactive site. In addition, Nalpha-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide can also be used as a fluorescent probe for protease activity in analytical methods. The product research on this compound has shown that it is a potent inhibitor of cyclic peptide synthetases and can be used as an anti-inflammatory agent.</p>

<p>Please enquire for more information about 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Bromoquinolin-8-amine is a topoisomerase inhibitor that can be used as an antitumor agent. It has been shown to inhibit the growth of tumor cell lines and suppress the growth of colon carcinoma cells in rats and human colon carcinomas in mice. 5-Bromoquinolin-8-amine interacts with DNA, specifically inhibiting the formation of supercoiled DNA. This interaction may lead to the inhibition of tumor cell growth. 5-Bromoquinolin-8-amine also inhibits protein synthesis by interacting with proteins at the ribosomal level, leading to inhibited cell growth.</p>

<p>Please enquire for more information about 1-Bromo-9-(4,4,5,5,5-pentafluoropentylthio)nonane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>ACV trifluoroacetate salt H-Aad (Cys-D-Val-OH)-OH trifluoroacetate salt is a nonheme iron that has been shown to be an oxidizing agent. It is used in the synthesis of antibiotics and other organic compounds. ACV trifluoroacetate salt H-Aad (Cys-D-Val-OH)-OH trifluoroacetate salt also has synthetase activity, which catalyzes the formation of a thiolate ligand from two molecules of acetyl coenzyme A (ACCOA) and one molecule of propionyl coenzyme A (PCCOA). This ligand binds to metal ions such as Fe2+, which are then reduced to Fe3+ by the metal cluster. The water ligands on the coordination sphere may be replaced by other ligands, such as lysine.</p>

<p>1,3-Difluoro-2-vinylbenzene is a hydroborating reagent that can be used to make alcohols from alkyl halides. It is also a potential sensor for the environment and has linearity in its response. 1,3-Difluoro-2-vinylbenzene may be an alternative to traditional hydroborating agents, such as diborane, which are toxic and expensive. This compound is sensitive to moisture and should be stored under nitrogen or argon gas.</p>

<p>Please enquire for more information about N,N'-Dimethyl-2,7-Diazapyrenium bistetrafluoroborate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (D-Tyr5,D-Trp6)-LHRH trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Chlorouracil is a drug that is used to treat cancer. It has been shown to have biological properties, and its mechanism of action is not yet fully understood. 5-Chlorouracil can be synthesized in the laboratory by reacting sodium hydroxide with 5-chloro-2,4(1H,3H)-pyrimidinedione. In wastewater treatment plants, it reacts with organic matter in the water to form nontoxic products, such as carbon dioxide and urea. The reaction solution contains 5-chlorouracil, which undergoes tautomerization spontaneously or through the addition of base. This reaction is reversible, and both the erythro and threo forms are present in solution at equilibrium. The biological properties of 5-chlorouracil have been investigated using sublethal doses in experimental animals. In one study, 5-chlorouracil was found to inhibit xanthine oxidase activity in rats significantly more</p>

<p>Please enquire for more information about Alpha-Helical CRF (9-41) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Z-Val-Lys-Lys-Arg-4MbNA is a synthetic peptide that is used for staining of fixed cells. It binds to lysosomal membrane proteins and stains with a red color when reacted with a chromogen. This product is used as an intermediate in the production of monoclonal antibodies. Z-Val-Lys-Lys-Arg-4MbNA is also used to detect lysosomes in unfixed cells by histochemically staining the reaction product with a solution of buffers and biochemical, following incubation at 37°C for 24 hours. This product has been shown to bind to cellular morphology, fibroblasts, and stained tissue sections.</p>

<p>Please enquire for more information about PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rhodium(III) chloride hydrate is a catalyst that is used in the oxidation of aromatic hydrocarbons. It has been shown to have an acidic reaction with hydrochloric acid and is used in the oxidation of benzene, toluene, ethylbenzene, and xylene. Rhodium(III) chloride hydrate has also been shown to be a good catalyst for the production of polycyclic aromatic hydrocarbons from light emitting diodes. This product can be used as an oxidizing agent in organic synthesis reactions. The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of</p>

<p>A carboxyl-terminal cleavage product of collagen 6 alpha-3 chain which is produced and released by adipocytes and massively upregulated in malignant tumors of breast, liver colon and pancreas. Endotrophin provides a link between obesity and aggressive tumor growth and may serve as sensitive diagnostic marker and valid therapeutic target for designing better strategies to treat cancer and ameliorate obesity-induced insulin resistance.</p>

<p>Please enquire for more information about Z-Tyr-Val-Ala-DL-Asp-fluoromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ([13C6]Leu5)-Ghrelin (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 3,5-dichloro-4-methoxybenzoate is a fine chemical and useful building block for research chemicals. It belongs to the class of speciality chemicals and can be used as a reagent in organic synthesis. Methyl 3,5-dichloro-4-methoxybenzoate is a versatile building block that has been reported in the synthesis of many complex compounds. This compound can also be used as an intermediate or scaffold for medicinal chemistry applications.</p>

<p>Please enquire for more information about Galanin-Like Peptide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Catestatin (human) trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4,5-Dibromo-1,2,6,7-tertahydro-8H-indeno[5,4-b]furan-8-one is a chemical reagent that is used for the debromination of ethyl cyanoacetate. The nucleophilic nature of the hydroxyl group in the target compound makes it an efficient substrate for this reaction. This reagent can be used to synthesize ramelteon which is a drug approved by the U.S. Food and Drug Administration (FDA) for insomnia treatment. This high yield synthesis highlights 4,5-dibromo-1,2,6,7-tertahydro-8H-indeno[5,4b]furan-8one's usefulness as a debrominating agent.</p>

<p>Please enquire for more information about 1b-(4-Fluorophenyl)hexahydro-',7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic Acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Urotensin II is a peptide that is expressed in the brain and has hypotensive effects. It is an endogenous ligand for the urotensin II receptor, which is found in various tissues including the heart, vascular system, and lungs. Urotensin II-Related Peptide (URP) was identified from cDNA sequences of human, mouse, and rat tissues. The URP consists of a sequence of amino acids with a molecular weight of 1219. This peptide has been shown to have diagnostic use in tissues and animals as well as being immunoreactive in monoclonal antibodies. The gene encoding URP has been cloned and its protein product has been characterized by mass spectroscopy.</p>