Organic Halides

<p>Applications 2-Bromothiophene (cas# 1003-09-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-amino-N,N-dimethylethane-1-sulfonamide hydrochloride (cas# 91893-69-5) is a useful research chemical.<br></p>

<p>Applications Phosphorodichloridic Acid is an intermediate used in the synthesis of Cefotiam Dihydrochloride-13C, 15N2 (C243007), which is labelled Cefotiam Dihydrochloride (C243005), which is an antibiotic product used in injections to treat bacterial infections. Cefotiam Dihydrochloride can also reduce allergic reactions and mixed with pharmaceutical carriers for medical formulations.<br>References Jiang, C., et al.: Faming Zhuanli Shenqing, CN 105646539 A, 20160608 (2016); Liu, X.: Faming Zhuanli Shenqing, CN 105193819 A, 20151230, (2015); Weng, Y., et al.: Faming Zhuanli Shenqing, CN 103601737 A. 20140226 (2014)<br></p>

<p>Applications 4-Bromo-2-nitroaniline is used for the synthesis of reagents such as ethyltriphenylphosphonium tribromide;<br>References Jamir, L., et al.: Synthetic. Comm., 41, 147 (2011); Reuter, R., et al.: Euro. J. Org. Chem., 32, 5647 (2009);<br></p>

<p>Applications 2,6-DIBROMO-3-PICOLINE (cas# 887571-15-5) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Chlorobutanal Dimethyl Acetal 90% is a compound useful in organic synthesis and other chemical processes. It is used as an intermediate in the synthesis of aripiprazole, buspirone, and NAN-190 via reductive alkylation of piperazine derivatives with aldehydes<br>References Kowalski, P., et al.: Archiv der Pharmazie, 345, 81 (2012)<br></p>

<p>Applications 4-{[(p-Fluorophenyl)imino]methyl}phenol is used in the preparation of benzylacetones which promote anti-fungal activity.<br>References Sandhar, R. et al.: J. Ind. Council Chem., 22, 32 (2005);<br></p>

<p>Applications 4-Bromo-2-ethylphenol (cas# 18980-21-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 6-Bromohexanoic Acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosen, D. B., et al.: PCT Int. Appl. (2020), WO 2020254617 A1<br></p>

<p>Applications 2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-one is an intermediate used to prepare aminothiazoles as therapeutic leads for prion diseases. It is also used in the synthesis of pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.<br>References Gallardo-Godoy, A., et al.: J. Med. Chem., 54, 1010 (2011); Keith, J., et al.: Bioorg. Med. Chem. Lett., 17, 2603 (2007)<br></p>

<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>

<p>Applications tert-Butyl 6-Chloro(R)-hydroxy-3-oxohexanoate is a chiral reagent used in the synthesis of callystatin A, a polyketide natural product that functions as an antibiotic. Also an impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Enders, D. et al.: Chem. A. Eur. J., 8, 4274 (2002);<br></p>

<p>Applications 4-(Bromomethyl)-2-fluorobenzonitrile is a useful building block for the preparation and optimization of the highly selective GLUT1 inhibitor, BAY-876.<br>References Siebeneicher, H., et al.: ChemMedChem, 11, 2261-2271 (2016);<br></p>

<p>Applications 3-​Amino-​5-​bromobenzotrifluorid​e is a general chemical reagent used in the synthesis of is a general chemical reagent used in the synthesis of trifluoromethylphenyl derivatives of methylguanidines as PET radioligands.<br>References aumiec, G. et al.: J. Med. Chem., 58, 9722 (2015);<br></p>