Toxicology

<p>Applications Hydroxychlorothalonil is a metabolite of Chlorothalonil (C411250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Katayama, A., et al.: J. Pest Sci., 22, 12 (1997), Godard, T., et al.: Mutat. Res., 444, 103 (1999), Zeng, L., et al.: Appl. Microbiol. Biotechnol., 79, 881 (2008), Wang, G., et al.: J. Bacteriol., 192, 2737 (2010),<br></p>

<p>Applications Labelled Tamsulosin. Specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),<br></p>

<p>Applications Terbufoxon Sulfoxide is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food Chem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008); Polgar, L. et al.: J. Chrom. A., 1249, 83 (2012);<br></p>

<p>Stability Light Sensitive<br>Applications A metabolite of Ethoxyquin. An oxidation product of the antidegradant Ethoxyquin found in the muscle of Atlantic salmon.<br>References Kahl, R., et al.: Toxicology, 28, 229 (1983), Burka, L., et al.: Xenobiotica, 26, 597 (1996), Bammler, T., et al.: Toxicol. Sci., 54, 30 (2000), Hayes, J., et al.: Cancer, 174, 103 (2001),<br></p>

<p>Applications Profenofos is a broad-spectrum organophosphorous pesticide that is used widely in cotton fields for insect control (1). Acetylcholinesterase inhibiting organophosphoric pesticide (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Martin, T. et al.: J. Econ. Entomol. 2003 Apr;96(2):468-74.2. Kushwaha, M. et al.: J Environ Qual. 2016 Sep;45(5):1478-1489.<br></p>

<p>Applications It is a major metabolite of Nicotine in humans. Carcinogen.<br>References Byrd, G., et al.: Drug Metab. Dispos., 20, 192 (1992), Benowitz, N., et al.: Br. J. Clin. Pharmacol., 51, 53 (2001), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Ethell, B., et al.: Biochem. Pharmacol., 65, 1441 (2003), Yamanaka, H., et al.: Eur. J. Pharm. Sci., 22, 419 (2004),<br></p>

<p>Applications A labelled metabolite of S-propylcysteine.<br>References Jones, A.R., et al.: Xenobiotica, 10, 827 (1980), 25) Ramu, K., et al.: Chem. Res. Toxicol., 8, 515 (1995), Krause, R., et al.: Drug Metab. Dispos., 25, 1013 (1997), Powley, M., et al.: Chem. Res. Toxicol., 16, 1448 (2003),<br></p>

<p>Applications Glutaric Acid-1,5-13C2 (cas# 1185108-16-0) is a compound useful in organic synthesis.<br></p>

<p>Applications The methylated analogue of Isobutyryl L-Carnitine (I780500). 2-Methylbutyryl-L-Carnitine is one of the acylcarnitines profiled from blood or plasma samples in the diagnosis of inborn errors of metabolism.<br>References Rashed, M.S. et al.: Pediat. Res., 38, 324 (1995); Frazier, D.M. et al.: J. Inher. Metab. Dis., 29, 76 (2006);<br></p>

<p>Applications PhIP (A617000) derivative. Carcinogen.<br></p>

<p>Applications Nafronyl is a selective inhibitor of serotonin receptors. Nafronyl is a vasodilator used in the treatment of intermittent claudication.<br>References Fontaine, et al.: Chim. Ther., 4, 44 (1969), Bessin, P., et al.: Eur. J. Med. Chem., 10, 291 (1975), Clyne, C.A., et al.: Br. J. Surg., 67, 347 (1980),<br></p>

<p>Applications Mancozeb is a mixture of Maneb (M163500) and Zineb, a manganese and zinc (1:1) complex mixture with the ethylene bis(dithiocarbamate) anionic ligand. Mancozeb is a foliate fungicide used to protect crops in agriculture. Mancozeb has a broader and more effective fungacidal activity than either of its component on their own. Mancozeb also significantly enhances the copper activity against several bacteriosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tang, M. et al.: Turang Tong., 41, 1365 (2010); Navneet; M. et al.: J. Ind. Botan. Soc., 74, 19 (1995); Lecigne, P. et al.: Phytoma, 531, 13 (2000);<br></p>