Toxicology

<p>Applications Cilastatin Sulfoxide is a derivative of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.<br>References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),<br></p>

<p>Applications A metabolite of Aflatoxin B1; a hepatocarcinogen in many animal models and probably a human carcinogen. It is produced by the predominant forms of cytochrome P 450 enzymes responsible for the biotransformation of AFB1. It shows potential predictive value as a marker for exposure and risk of dietary aflatoxins.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mykkaenen, H., et al.: Int. J. Cancer, 115, 879 (2005); Van Vleet, T.R. et al.: J. Toxicol. Environ. Health, 65, 853 (2002);<br></p>

<p>Applications epi-Aflatoxin Q1 is the 3R-epimer of Aflatoxin Q1 (A357530). epi-Aflatoxin Q1 is the less soluble isomer of Aflatoxin Q1 and is identical with the natural metabolite of Aflatoxin Q1.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mykkaenen, H. et al.: Int. J. Cancer, 115, 879 (2005); Van Vleet, T.R. et al.: J. Toxicol. Environ. Health, 65, 853 (2002);<br></p>

<p>Applications Isotope labelled Parathion (P192220) is an organophosphate insecticide used on cotton, rice and fruit trees.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seifert, J., et al.: Environ. Toxicol. Pharmacol., 35, 200 (2013); Ciffroy, P., et al.: Environ. Toxicol. Chem., 32, 602 (2013);<br></p>

<p>Applications 2-(Sulfoacetamido) Dimoxystrobin Acetic Acid is a metabolite of Dimoxystrobin (D480530) a pesticide component used for its antifungal activity.<br>References Hvezdova, M. et al.: Sci. Total. Env., 613-614, 361 (2018);<br></p>