Toxicology

<p>Applications 2-chloro-N-(2-ethyl-6-methylphenyl)acetamide (cas# 32428-71-0) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Bensulide, is an organophosphate acetylcholinesterase inhibitor used as an herbicide (1) in the protection of crops through pesticides (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Lisker, E. et al.: Bull. Environ. Contam. Toxicol. 2011 Oct;87(4):355-60.2. Pinkerton, T. et al.: Methods Mol. Biol. 2012;847:11-23.<br></p>

<p>Applications Used to stimulate root formation of plant clippings. Suitable for plant cell culture tested.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Handa, A., et al.: Plant Physiol., 69, 514 (1982), Polanco, C., et al.: Plant Sci., 162, 817 (2002), Rzepka-Plevnes, D., et al.: J. Food Agric. Environ., 5, 194 (2007),<br></p>

<p>Applications A metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>

<p>Applications An aryloxyphenoxypropionate (AOPP) post-emergence herbicide that shows an exclusive whole plant safety to rice with a high control efficacy to annual grass weeds, especially barnyardgrass.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Doroh, M.C. et al.: Weed Technol., 26, 97 (2011); Zeng, Z. et al.: Nongyao, 43, 327 (2004); Kim, T.J. et al.: Cong. Proc. BCPC Int. Cong. Crop Sci. Technol., 2, 833 (2003);<br></p>

<p>Applications Chemotherapy drug used to treat cancer of the bladder.<br>References Steinberg, G., et al.: J. Urol., 163, 761 (2000); Christmann-Franck, S., et al.: J. Med. Chem., 47, 6840 (2004); McKiernan, J., et al.: J. Clin. Oncol., 24, 3075 (2006); Steinberg, G., et al.: Drug Evaluation, 2, 1009 (2001)<br></p>

<p>Applications 2-Chloroethyl)phosphonic acid (Ethephon) is the most widely used plant growth regulator. Ethephon is often used on wheat, coffee, tobacco, cotton, and rice in order to help the plant's fruit reach maturity more quickly. The toxicity of Ethephon is actually very low, and any Ethephon used on the plant is converted very quickly to ethylene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brantley, B., et al.: J. Plant Physiol., 1428, 741 (1960), Ntui, V., et al.: J. Food Agricult. Environ., 5, 211 (2007), Vwioko, E., et al.: Biosci. Res. Communic., 21, 263 (2009),<br></p>

<p>Applications Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>

<p>Applications Sotalol (cas# 3930-20-9) is a useful research chemical.<br></p>

<p>Applications Isotope labelled 2-Phenylphenol (P335870), which is an agricultural fungicide and is no longer used as a food additive (1). It has been associated with the incidence of bladder cancer in male rats which may be related to its primary metabolite, phenylhydroquinone (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gouin T. et al.: Environ Pollut. 2012 Jun;165:208-14.2. Balakrishnan, S. et al.: Environ Mol Mutagen. 2016 Apr;57(3):210-9<br></p>

<p>Applications Labelled Tetrabenazine. Dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>

<p>Applications Isotope labelled Epoxiconazole is a fungicide used to inhibit the metabolism and growth of mycelia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gromadzka, K., et al.: Cereal. Res. Commun., 40, 518 (2012); Chen, Yu,, Plant. Disease., 96, 1495 (2012); Echeverria-Saenz, S., et al.: Sci. Total. Environ., 440, 106 (2012);<br></p>

<p>Applications Labelled Talinolol. Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>

<p>Applications Diuretic; antihypertensive. A subunit-specific inhibitor of GABAC receptors.<br>References Wentling, C.D., et al.: Anal. Profiles Drug Subs., 1, 65 (1972), Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999), Qian, H., et al.: J. Neurobiol., 40, 67 (1999), Qian, H., et al.: Mol. Pharmacol., 67, 470 (2005), Hadley, S., et al.: J. Physiol., 581, 1001 ( 2007),<br></p>

<p>Applications Iron Saccharate has been used to treat iron deficiency and iron deficiency anemia associated with different chronic diseases.<br>References Stein, J., et al.: Curr. Med. Res. Opinion, 28, 241 (2012),<br></p>

<p>Applications Paraquat is a quarternary nitrogen compound that is used as an herbicide to eliminate unwanted weeds and grasses by inducing superoxide production in the mitochondria, causing a great deal of oxidative damage. Paraquat is highly toxic to humans, causing acute poisoning, lung damage and death. Paraquat is also thought to cause Parkinson’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cochemé, H., &amp; Murphy, M.: J. Biol. Chem., 283, 1786 (2008); Suntres, Z.: Toxicology, 180, 65 (2002); Yang, W., et al.: J. Toxicol. Env. Heal. Part A: 71, 289 (2008)<br></p>

<p>Applications Sarolaner is used in the making of formulations for the control of ticks in cats, and flea infestations in dogs. A parasiiticide.<br>References Vatta, A. F., et al.: Veterinary Parasitol., 270, S19 (2019), Packianathan, R., et al.: Parasit. Vectors, 10, 387 (2017)<br></p>