Biochemicals and Reagents

Applications Black PN is a synthetic dye used in foods and cosmetics. Additive. Also used as a modulator of adenosine A1/A3 receptors as potential therapeutic agents for conditions involving metabolic stress. Dyes and metabolites, Environmental Testing.
References Ganesan, L. et al.: Biochem. Pharm., 81, 810 (2011)l; Aguilar, F. et al.: EFSA J., 8, 1540 (2010); May, L. et al.: Mol. Pharm., 77, 678 (2010);

Applications L-Lysine-2,6,6-d3 HCl is a useful isotopically labeled compound of L-Lysine HydrochlorideDISCONTINUED PLEASE SEE L486915 (L468923)

Impurity Cholecalciferol EP Impurity A
Stability Light Sensitive, Temperature Sensitive
Applications 5,6-trans-Vitamin D3 (Cholecalciferol EP Impurity A) is the major photoisomer of Vitamin D3 analog, as an impurity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bikle, D., et al.: Biochemistry, 25, 1545 (1986), Webb, A., et al.: J. Clin. Endocrinol. Metab., 68, 882 (1989), Baran, D., et al.: J. Cell Biochem., 50, 124 (1992), Tian, X., et al.: J. Biol. Chem., 268, 14888 (1993),

Applications S-Phenylmercapturic Acid-d5 is the labelled analogue of S-Phenylmercapturic Acid (P335600), an important metabolite of Benzene.
References Qu, Q., et al.: Am. J. Ind. Med., 37, 522 (2000); Ghittori, S., et al.: Int. Arch. Occup. Environ. Health, 67, 195 (1995);

Applications Labelled L-Methionine, an essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier.
References Benevenga, N.J., et al.: J. Agric. Food Chem., 22, 2 (1974), Fleisher, L.D., et al.: Clin. Endocrinol. Metab., 3, 37 (1974), Meinnel, T., et al.: Biochimie, 75, 1061 (1993),

Stability Light Sensitive
Applications Indigo carmine is a dye consisting of an indigo dimer with sodium salts of sulfonic acids at positions 5 and 5'. This compound has been used as a tissue stain, pH indicator, and tool for the determination of hypochlorite in solutions.
References 1. Reinle, G.G. and Depuy, E.S. 1920. Cal State J Med. 18: 49-52. PMID: 187381042. Monson, F.C., et al. 1991. J. Urol. 145: 842-845. PMID: 20057163. Harriram, A., et al. 2003. J Environ Sci Health A Tox Hazard Subst Environ Eng. 3: 1055-1064. PMID: 127749084. Archer, T.L. 2009. J Clin Anesth. 21: 544-546. PMID: 200062695. Lee, B.E., et al. 2010. BMC Gastroenterol. 10 97. PMID: 207318306. Park, H.J., et al. 2010. J Clin Ultrasound. 38: 305-308. PMID: 20544866

Applications 11beta-Hydroxyprogesterone (CAS# 600-57-7) is a useful research chemical compound.

Applications Pigment Red 146 can be used for aqueous inkjet set and inkjet printing.
References Masatoki, M., et.al.: Jpn. Tokkyo Koho, 52, (2021);

Applications A red azoic dye. Dyes and metabolites, Environmental Testing
References Hoover, K., et al.: Chem. Res. Toxicol., 18, 1497 (2005), Altenburger, R., et al.: Environ. Toxicol. Chem., 24, 324 (2005), Gonzalez, M., et al.: Bioorg. Med. Chem., 13, 1775 (2005),

Applications Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.
References Fukada, S., et al.: J. Nut., 136, 2797 (2006), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006), Yamada, T., et al.: Biochem. Pharmacol., 73, 981 (2007), Enman, J., et al.; J. Agric. Food Chem., 56, 2609 (2008),

Applications Used in peptide synthesis.
References Flohr, S., et al.: Chem. Eur. J., 5, 669 (1999), Kadereit, D., et al.: ChemBioChem., 1, 144 (2000), Volkert, M., et al.: Biol. Chem., 382, 1133 (2001),

Applications Pigment Yellow 42 is used in the topical solar composition protecting skin exposed to irradiation of high energy visible light.
References Thorel, J. N.: Fr. Demande 36 pp. (2020)

Applications Biotinyl Tyramide is a Biotin (B389040) derivative, a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.
References Griesser, R. et al.: Biochem., 12, 1917 (1973); du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942); Traub, et al.: Nature, 178, 649 (1956); Siegel, H., et al.: Experienta, 37, 789 (1981); Vesely, D.L., Science, 216, 1329 (1982); Hugues, M., et al.: Biochemistry, 31, 12 (1992);

Applications L-Allo-isoleucine-d10 is a derivative compound of L-allo-isoleucine (A548200), which has been suggested to induce epithelial β-defensin expression. In addition, L-allo-isoleucine is utilized in the biosynthesis pathway for coronamic acid.
References Fehlbaum, P., et al.: Proc. Natl. Acad. Sci. USA 97, 12723 (2000); Parry, R. J., et al.: J. Am. Chem. Soc. 113, 1849 (1991)

Applications N-(2,4-Dimethylphenyl)-3-oxobutanamide (cas# 97-36-9) is a useful research chemical.

Applications Tocofersolan is a polyethylene glycol derivative of α-Tocopherol (T526125). Tocofersolan is a synthetic water-soluble vitamin E unlike its natural counterpart which are fat soluble. Tocofersolan is used in pediatrics in the treatment vitamin E-deficient cholestatic children. Tocofersolan has potential application as a absorption enhancer in drug delivery systems. Typical batch, n = 21
References Socha, P. et al.: J. Pediatric Gastroenterol. Nutr., 24, 189 (1997); Chang, T. et al.: Clin. Pharmacol. Therap., 59, 297 (1996); Wu, S.H.W. et al.: Pharmac. Technol., 23, 52 (1999);