Biochemicals and Reagents

<p>Serotonin uptake inhibitor; anti-depressant</p>

<p>Ac-CSLTVNDTGEY-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CSLTVNDTGEY-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CSLTVNDTGEY-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CSLTVNDTGEY-NH2 at the technical inquiry form on this page</p>

<p>H-VPKKPKRKKRRRRNVNCLK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VPKKPKRKKRRRRNVNCLK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VPKKPKRKKRRRRNVNCLK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VPKKPKRKKRRRRNVNCLK-OH at the technical inquiry form on this page</p>

<p>GNE-149 is a small molecule that is orally bioavailable and has anticancer activity. It binds to the target of the drug, which is involved in cancer cell proliferation, leading to cell death. GNE-149 has been shown to be effective against ER+ breast cancer cells in vitro and in vivo through an estrogen receptor-mediated mechanism.</p>

<p>H-ADSNPRGVSAYLSRPAPGGC-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ADSNPRGVSAYLSRPAPGGC-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ADSNPRGVSAYLSRPAPGGC-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ADSNPRGVSAYLSRPAPGGC-OH at the technical inquiry form on this page</p>

<p>H-RELKNSAISLLDTIA-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-RELKNSAISLLDTIA-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-RELKNSAISLLDTIA-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-RELKNSAISLLDTIA-OH at the technical inquiry form on this page</p>

<p>Please enquire for more information about Anti-Kat2 antibody - 2mg/mL including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Anti-IL34 antibody R3G - 2mg/mL including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-ANDPVFVVLHSFTDA-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ANDPVFVVLHSFTDA-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ANDPVFVVLHSFTDA-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ANDPVFVVLHSFTDA-OH at the technical inquiry form on this page</p>

<p>A kit for releasing EVs from their bound state with the Vn96 peptide.</p>

<p>H-HRCQAIRKK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-HRCQAIRKK-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-HRCQAIRKK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-HRCQAIRKK-OH at the technical inquiry form on this page</p>

<p>H-ARMVSKS-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ARMVSKS-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ARMVSKS-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ARMVSKS-OH at the technical inquiry form on this page</p>

<p>AMC conjugated molecule targeting caspase-8 and granzyme B</p>

<p>Z-Gly-Met-OH is a buffer that can be used to create an acidic solution. It is often used in liquid chromatography and peptide synthesis. Z-Gly-Met-OH has been shown to have potential use as an enzyme inhibitor, specifically for proteases and peptidases. The hydrolyzed form of Z-Gly-Met-OH has been shown to bind zinc ions and could be used in the treatment of metal ion poisoning.</p>

<p>Cyclo(Arg-Gly-Asp-D-Tyr-Lys) is a new synthetic peptide with anticancer activity. It has been shown to inhibit the growth of bladder cancer cells in vitro and in vivo, with no evidence of toxicity to normal bladder cells. Cyclo(Arg-Gly-Asp-D-Tyr-Lys) is a light sensitive molecule that can be delivered by an injection or as a pill. The peptide has been shown to have synergistic anticancer effects when combined with epirubicin, a chemotherapeutic drug used for the treatment of solid tumours, such as glioma and other cancers. Cyclo(Arg-Gly-Asp-D-Tyr-Lys) is also taken up by cells and causes DNA damage at the cellular level, leading to apoptosis.</p>

<p>Fmoc-Trp(Boc)-Wang resin is a solid phase peptide synthesis resin that can be used to synthesize peptides. It contains an amino acid sequence of Trp-Boc-Wang, which has been shown to inhibit the activity of ion channels. Fmoc-Trp(Boc)-Wang resin is also a useful tool for studying protein interactions and receptor binding. This resin is manufactured by Applied Biosystems, Inc., and is available in 100-200 mesh size. The product comes with a 1% DVB content and purity of &gt;97%.</p>

<p>H-GLEIDVTDFK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-GLEIDVTDFK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-GLEIDVTDFK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-GLEIDVTDFK-OH at the technical inquiry form on this page</p>

<p>FA-Gly-Leu-Ala-OH TFA is a high quality reagent that can be used for the synthesis of complex compounds. It is an intermediate for the production of fine chemicals and speciality chemicals, which are used as reaction components in the synthesis of versatile building blocks. This compound is also an excellent scaffold for research chemicals and useful as a building block in the synthesis of speciality chemicals.</p>

<p>H-AVIFM-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-AVIFM-OH is provided at greater that Crude (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-AVIFM-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-AVIFM-OH at the technical inquiry form on this page</p>

<p>H-LNLFSLDPDIDTLK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LNLFSLDPDIDTLK-OH is provided at greater that Flashpure (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LNLFSLDPDIDTLK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LNLFSLDPDIDTLK-OH at the technical inquiry form on this page</p>

<p>H-VVVGAGGV-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VVVGAGGV-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VVVGAGGV-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VVVGAGGV-OH at the technical inquiry form on this page</p>

<p>Acid Red 154 is a pigment that is soluble in organic solvents and has an acidic nature. It is a reddish-brown liquid with a particle diameter of 10-20 nm. This product is used as a dye, and it has been shown to have low toxicity. Acid Red 154 contains hydrogen peroxide, which is the active substance responsible for its color change. The dyestuff can be used in printing inks or as an additive to coatings and plastics.</p>

<p>Ac-SYSTTAVVTNC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-SYSTTAVVTNC-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-SYSTTAVVTNC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-SYSTTAVVTNC-NH2 at the technical inquiry form on this page</p>

<p>Methotrexate is a chemotherapeutic and immunosuppressive medication, which is a synthetic analog of folic acid. Its source is through chemical synthesis, mimicking the structure of dihydrofolate in order to exert its effects. Methotrexate acts primarily by inhibiting the enzyme dihydrofolate reductase (DHFR), leading to a decrease in tetrahydrofolate production. This disruption in folate metabolism results in the inhibition of DNA, RNA, and protein synthesis, which affects rapidly dividing cells.Methotrexate is employed broadly in clinical oncology as an antineoplastic agent, particularly in the treatment of leukemias, lymphomas, breast cancer, and osteosarcoma. Additionally, it serves as a cornerstone for managing autoimmune diseases such as rheumatoid arthritis and psoriasis, where it helps modulate the aberrant immune response. The dual role of Methotrexate in oncology and immunosuppression underscores its versatility and critical importance in therapeutic regimens. However, its use demands careful monitoring due to potential adverse effects on non-cancerous cells and organ systems, necessitating precise dosage management and patient evaluation.</p>

<p>Gly-Gly-Gly-Gly-Arg-Gly-Asp-Ser-Pro is a peptide used as an activator in research. It can be used to study protein interactions and the effects of ligands on ion channels and receptors. Gly residues are able to form hydrogen bonds, which is why they are often used as spacers in proteins. This peptide has a high purity and CAS number.</p>

<p>H-VSAADICGL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VSAADICGL-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VSAADICGL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VSAADICGL-OH at the technical inquiry form on this page</p>

<p>Please enquire for more information about Hepcidin-25 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-QNEAFSLTAK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-QNEAFSLTAK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-QNEAFSLTAK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-QNEAFSLTAK-OH at the technical inquiry form on this page</p>

<p>Class 1 PI3K enzyme inhibitor; anti-neoplastic</p>

<p>H-Asn-2-ClTrt-Resin (100-200 mesh) 1% DVB is a building block for the synthesis of peptides. It is a resin that contains amines, thiols, and alcohols. The resin has a particle size of 100 to 200 mesh and contains 1% DVB.</p>

<p>Canine Coronavirus Nucleocapsid Antigen, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Canine Coronavirus Nucleocapsid Antigen, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>H-PLLALLALWGPDPAAAF-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-PLLALLALWGPDPAAAF-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-PLLALLALWGPDPAAAF-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-PLLALLALWGPDPAAAF-OH at the technical inquiry form on this page</p>

<p>H-Gly-Phe-AMC is a synthetic substrate that is used in homogeneous enzyme assays. This product has been shown to have inhibitory properties against proteolytic enzymes such as peptidases, which are enzymes that break down proteins. H-Gly-Phe-AMC is also reactive with collagen and has been shown to be useful in the study of biochemical properties of peptide hormones.</p>

<p>Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Antigen, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Crimean-Congo Haemorrhagic Fever Virus Nucleocapsid Antigen, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Crimean-Congo Haemorrhagic Fever Virus is a tick-borne virus that causes Crimean-Congo Haemorrhagic Fever (CCHF), a serious disease that can have a case fatality rate of up to 40% during outbreaks. The virus is an RNA virus from the Nairoviridae family and is transmitted mainly through bites from infected ticks (especially Hyalomma species) or through contact with blood or tissues from infected animals or people. It is found across Africa, the Balkans, the Middle East, and parts of Asia. Symptoms can include fever, muscle aches, dizziness, neck pain, and backache and it can progress to internal and external bleeding, liver failure, and shock. Currently there is no vaccine to combat this disease, or an antiviral treatment that has been officially approved.<br>The Crimean-Congo Haemorrhagic Fever Virus nucleocapsid antigen is a structural protein of the virus. It wraps around the viral RNA genome to form the nucleocapsid, protecting the RNA and helping the virus replicate inside host cells. It's highly abundant, highly conserved, and produced early during infection. This protein is therefore a prime target for use in the development of new diagnostic assays for Crimean-Congo Haemorrhagic Fever Virus detection. The fact that the nucleocapsid protein is immunogenic it can also be used in vaccine research.Cymit Quimica's recombinant Crimean-Congo Haemorrhagic Fever Virus antigen is the full-length nucleocapsid protein from strain Nigeria/IbAr10200/1970 expressed in E. coli and containing a His-tag at the C-terminus. This antigen is potentially suitable for development of serological assays, such as ChLIA, ELISA and lateral flow, to detect the presence of antibodies to CCHF virus in patient samples.</p>

<p>H-Leu-Tyr-OH is a biphasic response amide with two phenyl groups and a primary amino group. It is most active at pH 6.5, but can be used at higher or lower pHs. The rate of H-Leu-Tyr-OH formation is highest in triticum aestivum (wheat) butyric acid extract. H-Leu-Tyr-OH has been shown to have excitatory effects on plant physiology, which may be due to its ability to bind to the specific antibody against acetylcholine receptors.</p>

<p>Ephb4 is a protein that in humans is encoded by the EPHB4 gene. This protein belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. It binds to its ligands, ephrin-A1 and ephrin-A2, as well as members of the ephrin-B class of ligands. The activation of this receptor leads to many downstream effects such as regulating cell migration, proliferation, differentiation, and survival. Ephb4 is an excellent research tool for studying human diseases such as cancer and cardiovascular disorders.</p>

<p>Ac-CRNRLSDRFKQGDESA-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CRNRLSDRFKQGDESA-NH2 is provided at greater that &gt;85% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CRNRLSDRFKQGDESA-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CRNRLSDRFKQGDESA-NH2 at the technical inquiry form on this page</p>

<p>A novel non-covalent inhibitor of the PLpro protease from SARS-CoV-2 and SARS-CoV viruses. GRL 0617 inhibits the proteolytic processing of the viral polypeptide. As PLpro also acts as a protease in pathways involved in innate immunity, there are indications that it can promote immunity against the virus.</p>

<p>Opioid receptor antagonist</p>

<p>Please enquire for more information about Plasmodium Falciparum HRP-2 (Malaria) Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Plasmodium LDH (Malaria) Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Asp(Ala-OH)-OH is an amino acid that has been found to be selectively active in the cerebral cortex. It has a high affinity for the cerebral cortex, with a Kd of 1.5 nM and a brain tissue concentration of 3.3 µg/g. H-Asp(Ala-OH)-OH has been shown to have neuroprotective effects against hypoxia, glutamate toxicity, and oxygen deprivation. This compound reverses the effects of oxidative stress in cultured cells and can also stimulate protein synthesis in cultured cells. The mechanism by which it works is not yet known but may involve inhibition of cysteine uptake into the cell or stimulation of protein synthesis by increasing intracellular levels of cAMP.</p>

<p>Kappa Free Light Chain, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Kappa Free Light Chain, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Human Sera-Gammopathy is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Human Sera-Gammopathy including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Ac-TEAAGAM-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-TEAAGAM-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-TEAAGAM-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-TEAAGAM-NH2 at the technical inquiry form on this page</p>

<p>Dipeptidyl peptidase 4 (DPP4) inhibitor</p>

<p>Analeptic</p>

<p>H-SGQQQGLPRAAGGSVPC-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-SGQQQGLPRAAGGSVPC-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-SGQQQGLPRAAGGSVPC-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-SGQQQGLPRAAGGSVPC-OH at the technical inquiry form on this page</p>

<p>H-Glu[Cyclo(Arg-Gly-Asp-D-Tyr-Lys)]2 is a cyclic peptide that contains the sequence of amino acids Arg, Gly, Asp, D, Tyr and Lys. It is a peptide macrocycle that has been shown to be effective against tumor cells. This peptide has been derivatized for targeting purposes and has been shown to be an effective imaging agent for tumor cells in vivo. H-Glu[Cyclo(Arg-Gly-Asp-D-Tyr-Lys)]2 is also biochemically active and can inhibit the growth of cancer cells through multiple mechanisms.</p>