Immunology Antibodies
Found 2551 products of "Immunology Antibodies"
gp96-II
Heat shock protein gp96 inhibitor which binds to and antagonizes gp96 mediated lipopolysaccharide (LPS) induced cytokine production. Anti-inflammatory in a number of in vivo and in vitro models.
Molecular weight:4,461.6 g/molAAV8 capsid protein
This peptide represents part of the capsid protein, which forms the shell, of adeno-associated virus 8 (AAV8). This peptide has high major histocompatibility (MHC) affinity, and the MHC restriction has been identified as a H-2 Dd binder. This epitope can therefore simulate CD8+ T cells and can elicit a robust response from interferon γ (IFN-γ), a cytokine critical for innate immunity and adaptive immunity against viral, and some bacterial and protozoal infections.CD8+ T cells (often called cytotoxic T lymphocytes, or CTLs) are generated in the thymus and express the dimeric co-receptor, CD8, on their surface. CD8+ T cells can recognise peptides presented by MHC class I molecules, which are found on all nucleated cells. CD8+ T cells are important for defence against intracellular pathogens, including viruses and bacteria, and for tumour surveillance, however, they can also contribute to excessive immune responses that leads to immune-mediated damage.AAV8 is a non-disease causing virus that can infect humans and can integrate into the host cell genome. Gene therapy vectors have been created using AAV8 which can persist in an extrachromosomal state without integrating into the genome of the host cell and show promise in recent human clinical trials.
Molecular weight:855.4 g/molHuman IgA protein
The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is a powerful antituberculosis drug from the rifamycin class. It is specifically designed to combat tuberculosis infections by targeting the active compounds in mycobacterium. This bactericidal drug exhibits its potent activity by binding to DNA-dependent RNA polymerase, preventing transcription and replication. Its effectiveness has been demonstrated through rigorous testing using the patch-clamp technique on human erythrocytes. The drug undergoes various metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Additionally, it specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains and inhibits their growth in culture. Tilmicosin is a macrolide antibiotic widely used in veterinary medicine to treat respiratory disorders caused by bacteria such as Clostr
Purity:>95% By Sds-PageSheep IgM
Sheep IgM is a monoclonal antibody that is widely used in Life Sciences research. It plays a crucial role in various cellular processes, including the regulation of β-catenin and caspase-9. Sheep IgM also activates the mitogen-activated protein (MAP) signaling pathway, which is involved in cell proliferation, differentiation, and survival. This antibody has antiviral properties and can be used in immunoassays to detect specific antigens. Additionally, Sheep IgM has been shown to activate p38 MAP kinase and endonuclease activity. Purified Immunoglobulins derived from sheep have an acidic pH, making them suitable for use in a wide range of applications. Overall, Sheep IgM is a valuable tool for researchers studying various aspects of cell biology and immunology.
Purity:Min. 95%Pyruvate Kinase antibody (IgG fraction)
Pyruvate kinase antibody (IgG fraction) was raised in goat using pyruvate kinase isolated from rabbit Muscle as the immunogen.
Purity:Min. 95%Mouse IgG1
Mouse IgG1 is a monoclonal antibody that specifically targets the EBNA1 protein. This antibody is highly effective in detecting and quantifying the expression of EBNA1 in various biological samples. Mouse IgG1 has been extensively used in life sciences research, particularly in studies related to immunoglobulins and autoantibodies. This antibody exhibits high specificity and sensitivity, making it an ideal tool for researchers working on projects involving glycosylation, glycation, interferon, cholinergic acetyltransferase, and phosphatase activities. Its unique binding properties allow for accurate measurements of glycopeptide viscosity and other relevant parameters. Trust Mouse IgG1 to deliver reliable results for your research needs in the field of life sciences.
Purity:Min. 95%Human IgG Fc
Human IgG Fc is a monoclonal antibody that belongs to the class of immunoglobulins. It is derived from human serum and has a wide range of applications in the field of Life Sciences. Human IgG Fc plays a crucial role in immune responses, including neutralizing pathogens, activating complement systems, and facilitating antibody-dependent cell-mediated cytotoxicity (ADCC). This antibody is involved in various biological processes such as collagen synthesis, growth factor signaling, and regulation of immune responses.Purity:Min. 95%Human IgG Fc protein
The Human IgG Fc protein is a versatile and essential component in the field of Life Sciences. It plays a crucial role in various biological processes and has a wide range of applications. This protein is commonly used in research, diagnostics, and therapeutic development.
Purity:≥95% By Sds-PageCiita antibody
Ciita antibody was raised in rabbit using CIITA peptide corresponding to a region near the N-terminus of the human protein conjugated to KLH as the immunogen.
Purity:Min. 95%Human IgG Fc fragment
The Human IgG Fc fragment is a purified immunoglobulin that is commonly used in the field of life sciences. It is derived from human serum and has been activated through various processes such as fatty acid acetylation. This fragment plays a crucial role in immune responses by binding to specific receptors, including the growth factor-1 receptor, acidic growth factor, alpha-fetoprotein, telomerase, and antibodies. Additionally, it has been found to interact with chemokines and natriuretic factors. The Human IgG Fc fragment is widely utilized in research and diagnostic applications for its ability to accurately detect and quantify target molecules. Its high specificity and affinity make it an invaluable tool for studying immune responses and developing therapeutic interventions.Purity:≥95% By Sds-Page
