Heterocycles with Nitrogen (N)

Applications 5-(4-methylphenyl)imidazolidine-2,4-dione (cas# 69489-37-8) is a useful research chemical.

Applications (S)-1-Pyridin-2-yl-ethylamine (cas# 27854-90-6) is a useful research chemical.

Applications 5-Bromopyrimidine (cas# 4595-59-9) is a compound useful in organic synthesis.

Applications 5-fluoro-4-hydrazino-2-methoxypyrimidine (cas# 166524-64-7) is a useful research chemical.

Applications 5-(2-Methyl-1,3-dioxolan-2-yl)-2-pyridineethanol (cas# 184766-50-5) is a compound useful in organic synthesis.

Applications 4-Ethyl-1,3-Oxazolidin-2-One (cas# 16112-60-0) is a useful research chemical.

Applications 2-chloro-6-(piperidin-1-yl)pyridine (cas# 19946-28-2) is a useful research chemical.

Applications 1,2-Dimethylpiperazine (cas# 25057-77-6) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Miyamoto, T., et al.: J. Med. Chem., 33, 1645 (1990),

Applications 6,​8-​Dibromo-​3,​4-​dihydro-​3,​3-​bis(1-​pyrrolidinylmethyl)​-2H-1-benzopyran-4-ol is a useful synthetic reagent.

Applications 3-(Triethoxysilyl)propyl 2-((4-amino-5-hydrazinyl-4H-1,2,4-triazol-3-yl)thio)propanoate is a useful reagent for organic reactions.

Applications 6-Methylpyridine-3-amine, is a heterocyclic building block used in the manufacture of various pharmaceutical compounds. It can be used for the synthesis of 2-aminoquinazoline derivatives, as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators (mGluR5), leading toward a drug candidate for the treatment of l-DOPA induced dyskinesia.
References Kubas, H., et al.: Bioorg. Med. Chem. Lett., 23 (16), 4493 (2013);

Applications 2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is used as the starting material in the preparation of pyrazine derivatives that are AxI and c-Met receptor enzyme inhibitors. These inhibitors are useful in the treatment of tumors. 2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is also used in the preparation of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents.
References Rushton, L.; et al.: PCT Int. Appl. 119 pp. Patent 2009 CODEN:PIXXD2; Charrier, J-D.; et al.: J. Med. Chem, 54, 2320 (2011)

Applications 2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)