Heterocycles with Nitrogen (N)

<p>Applications 6-Desamino-6-oxo Phenazopyridine is a Phenazopyridine (P313751) degradation product/impurity, and is a useful synthetic intermediate.<br>References Nickerson, B., et al.: J. Liq. Chromatogr., 18, 3947 (1995)<br></p>

<p>Applications (R)-3-Aminopiperidine-2-one<br></p>

<p>Applications 3-Bromopropionic Acid N-Hydroxysuccinimide (cas# 101314-84-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Chloro-6-ethynylpyridazine is an pyridazine triflate intermediate used for the preparation of (alkynyl)pyridazine.<br>References Toussaint, D., et al.: Acta. Chimica, Slovenica., 41, 253 (1994);<br></p>

<p>Applications 1H-Pyrrole is a five membered heteroaromatic ring that is used as a synthetic intermediate to create products for the pharmaceutical, chemical, food and cosmetic industries. 1H-Pyrrole has the ability to undergo electrochemical polymerization, producing a durable, conductive film that can be used to coat biosensors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Diaz, A., et al.: J. Chem. Soc. Chem. Comm., 14, 635 (1979); Kaneto, K.: Curr. Appl. Phys., 5, 178 (2005); Lipshutz, B.: Chem. Rev., 86, 795 (1986)<br></p>

<p>Applications {2-[(Pyridin-4-ylmethyl)thio]-1,3-thiazol-4-yl}acetic acid (cas# 1040631-48-8) is a useful research chemical.<br></p>

<p>Applications Ethyl 4-Amino-2-mercaptopyrimidine-5-carboxylate (cas# 774-07-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Fluoropyridine-5-carbonyl chloride<br></p>

<p>Applications N-[1-[1-(4-Methoxyphenyl)-1H-tetrazol-5-yl]-1-methylpropyl]-1H-indole-3-ethanamine,<br></p>

<p>Applications 2,6-di-tert-Butylpyridine is used in the preparation of polymers with n-type nitroxide side groups to be used in organic radical batteries.<br>References Jaehnert, T., et. al.: Eur. Polymer J., 61, 105 (2014)<br></p>

<p>Applications 4-Aminopiperidine-3,3,4,5,5-d5 (CAS# 1219803-60-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-(3-Pyridinyl)-3-buten-1-amine is a useful synthetic intermediate.<br></p>

<p>Applications N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride (cas# 1219957-27-3) is a useful research chemical.<br></p>

<p>Applications Methyl 6-Amino-3,5-dibromopyridine-2-carboxylate is used as a reagent in the synthesis of imidazopyridines as Syk inhibitors. Also used as a reagent in the synthesis of quinoline, quinoxaline and naphthyridine derivatives as antibacterial agents.<br>References Blomgren, P., et al.: PCT Int. Appl. WO 2011112995 A1 20110915. Sep 15, 2011; Daines, R.A., et al.: PCT Int. Appl. WO 2007016610 A2 20070208. Feb 8, 2007<br></p>

<p>Applications N-(2-Chloroethyl)-N'-(4-pyridinyl)urea (cas# 62491-96-7) is a useful research chemical.<br></p>

<p>Applications 3-Amino-5-ethyl-5-phenylimidazolidine-2,4-dione (cas# 1139-11-3) could be useful for biological studies. An anticonvulsant.<br>References Lange, J., et al.: Pol. (1982), PL 123138 B1<br></p>

<p>Applications 2-Isopropylimidazole is a imidazole based compound, classified as a diazole and as an alkaloid. 2-Isopropylimidazole was investigated in animal studies as a new bone imaging agent.<br>References Wang, Y., et al.: Applied. Radiation. Isotopes., 69, 1169 (2011);<br></p>

<p>Applications 2,3-Dichloropyridine-5-boronic acid<br></p>

<p>Applications (4S)​-4-​Carboxy-​5,​5-​dimethyl-​α-​[[(5-​methyl-​3-​phenyl-​4-​isoxazolyl)​carbonyl]​amino]​-2-​thiazolidineacetic acid is a useful reactant for organic reactions.<br></p>

<p>Applications 2-Aminopyrimidine-5-boronic Acid Pinacol Ester is used in the preparation of phosphoinositide-3-kinases (PI3K) inhibitors.<br>References Burger, M.T. et al.: ACS Med. Chem. Lett., 2, 774 (2011); Heffron, T.P. et al.: J. Med. Chdem., 55, 8007 (2012);<br></p>

<p>Applications 2-Aminomethyl-3-nitropyridine is a derivative of 2-Methyl-3-nitropyridine (M320425).<br></p>

<p>Applications (S)-3-Hydroxypyrrolidin-2-one<br></p>

<p>Applications 4-Chloropyridine is used to synthesize Thrombin inhibitors, compounds that have potent anticoagulant activity. 4-Chloropyridine is also used as a reagent to synthesize Botryllazine A, a pyrazine alkaloid that exhibits cytotoxicity against human tumour cells.<br>References de Candia, M., et al.: J. Med. Chem., 56, 8696 (2013); Kodimuthali, A., et al.: Tetrahedron Lett., 50, 1618 (2009); Singh, P., et al.: J. Org. Chem., 78, 2639 (2013)<br></p>

<p>Applications 1-(4-aminophenyl)imidazolidin-2-one (cas# 89518-99-0) is a useful research chemical.<br></p>

<p>Applications N-Chloropiperidine is an intermediate used in the synthesis of 1-Piperidin-2-ylacetone (B449983), which is a useful research chemical.<br></p>

<p>Applications Reagent used in Guanidino transfers.<br></p>

<p>Applications N-Tosylpyrrole (cas# 17639-64-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(Phenylmethyl)-2-imidazolidinone (cas# 2385-38-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Boronopicolinic acid<br></p>

<p>Applications 1-(4-formylphenyl)-4-piperidinecarboxylic acid (cas# 727396-60-3) is a useful research chemical.<br></p>

<p>Applications Tris(4-pyridyl)-s-triazine is used in the preparation of metal-metallite coordination polymers as well as porphyrin prisms.<br>References Youm, K. et al.: Chem. Comm., 29, 3375 (2008); Li, M. et al.: CrystEngComm., 15, 1225 (2013);<br></p>

<p>Applications 2-(3-Fluorophenyl)pyrrolidine<br></p>

<p>Applications Pyridinium Formate is used as a doping agent to study different form of EHD processing for use ewith viscous surface tension solutions.<br>References Larsen, G., et al.: Adv. Mat., 16, 166 (2004);<br></p>

<p>Applications 3,5-Diethyl 1H-pyrazole-3,5-dicarboxylate<br></p>

<p>Applications 2,3-Pyrazinedicarboxylic Acid has been found to exhibit antifungal and antibacterial acitivity. It has also been used as a reagent in the preparation of transition metal pyrazinedicarboxylate complexes.<br>References Beaula, T.J., et al.: Spectrochim. Acta A, 138, 723 (2015); Premkumar, T., et al.: World J. Microb. Biot., 21, 479 (2005); Gunay, G., et al.: Inorg. Chim. Acta, 399, 19 (2013)<br></p>

<p>Applications 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a key intermediate in the synthesis of Riociguat, a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension.<br>References Arava, V., et al.: Pharma Chemica, 5, 232 (2013)<br></p>

<p>Applications N-Iodosuccinimide is a iodo substituted succinimide that is used as an iodinating agent in chemical synthesis.<br>References Castanet, A.-S. et al.: Tetrahed. Lett., 43, 5047 (2002);<br></p>

<p>Applications 4-Bromo-1H-1,2,3-triazoleare an important class of organic compounds, playing an important role in modern medicinal chemistry. Compounds with 1,2,3-triazole moieties are known to possess fungicidal, antimicrobial, antidepressant, antibacterial, anti-inflammatory, analgesic and antitumor activities.<br>References Sibgatulin, D. A., et al.: Synthesis, No. 7, 1075 (2010); Karivopalov, V. P., et al.: Chem. Rev. (Engl. Trans), 74, 339 (2005);<br></p>

<p>Applications 5-(4-methylphenyl)imidazolidine-2,4-dione (cas# 69489-37-8) is a useful research chemical.<br></p>

<p>Applications N-Benzyl-3-hydroxypiperidine has been used as a reactant in the preparation of optically active azidopiperidines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cochi, A., et. al.: Eur. J. Org. Chem., 2012, 2023 (2012)<br></p>

<p>Applications 1-(4-Nitrobenzyl)-1H-1,2,4-triazole is used in method for preparing Rizatriptan Benzoate intermediate.<br>References Chen, Y., et al.: Faming Zhuanli Shenqing, (2018);<br></p>

<p>Applications Reagent used in the synthesis of herbicides.<br>References Mekenyan, O., et al.: Chem. Res. Toxicol., 10, 994 (1997), Brown, T., et al.: Environ. Sci. Technol., 42, 5202 (2008),<br></p>

<p>Applications Oligomers of ethylene glycol have found widespread applications in a number of areas of chemistry, including the synthesis of crown ethers and podands, use as surfactants and more recently as biocompatible polymers which are capable of modifying the properties of a variety of substrates.<br>References Norgard, K., et al.: J. Biol. Chem., 268, 12764 (1993), Lin, C., et al.: Bioorg. Med. Chem., 3, 1625 (1995), Steegmaier, M., et al.: Nature, 373, 615 (1995), Murray, B., et al.: Biochemistry, 35, 11183 (1996),<br></p>

<p>Applications 1-cyclopropyl-3-phenylpiperazine (cas# 1248907-49-4) is a useful research chemical.<br></p>

<p>Applications Labelled 2-Chloropyridine (C380605). (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during the decomposition of specific insecticides. 2-CPY was found to be genotoxic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Demsia, G., et al.: Mutat. Res., 634, 32 (2007), Stapleton, D., et al.: Water Res., 43, 3964 (2009),<br></p>

<p>Applications 1H,4H,6H,7H-pyrano[4,3-c]pyrazol-3-ylmethanamine (cas# 933722-15-7) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of labelled indolizine compounds for use in antifungal combination therapy.<br></p>

<p>Applications 2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (cas# 169905-10-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 6'-Amino-1,6-dihydro-2-methyl-6-oxo[3,3'-bipyridine]-5-carbonitrile is a reagent used in the preparation of cardiotonic agents.<br>References Yamanaka, M. et al.: Chem. Pharm. Bull., 40, 666 (1992);<br></p>

<p>Applications 4-(3-Fluorophenyl)pyrimidin-2-amine (cas# 56875-59-3) is a useful research chemical.<br></p>

<p>Applications 2-Pyrazinecarbonyl Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br></p>

<p>Applications Intermediate for heterocyclic compounds as tyrosine kinase inhibitors and anticancer agents.<br>References McLean, A., et al.: J. Chem. Phys., 72, 5639 (1980), Watts, J., et al.: J. Biol. Chem., 276, 43197 (2001),<br></p>

<p>Applications 2-Amino-5-ethylpyrazine<br></p>

<p>Applications 2-Pivaloylamino-3-(α-hydroxybenzyl)pyridine (cas# 86847-67-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1H-Pyrrolo[2,3-b]pyridine 7-Oxide (cas# 55052-24-9) is a compound useful in organic synthesis.<br></p>

<p>Applications An aminopyridine derivative with potential herbicidal activity.<br>References Xiao, Y. et al.: Nongyao, 42, 15 (2003);<br></p>