Heterocycles with Nitrogen (N)

Applications 1H-1,2,3 Triazole-1-ethanol (cas# 74731-63-8) is a useful research chemical.

Applications Fmoc-(4-carboxymethyl)piperazine

Applications 1H-1,2,3-benzotriazol-5-amine (cas# 3325-11-9) is a useful research chemical.

Applications 5-Ethylpyridine-2-carboxylic Acid (cas# 770-08-1) is a compound useful in organic synthesis.

Applications 6-(3-aminophenoxy)pyridine-3-carbonitrile (cas# 1099689-56-1) is a useful research chemical.

Applications (4-Acetyl-Piperazin-1-Yl)-Acetic Acid is a useful research chemical. It is used in the preparation of phenylpiperidines as neurokinin NK1 and NK3 antagonists for treatment of neurokinin-mediated diseases
References O'Neill, B. T., et al.: From U.S. Pat. Appl. Publ. (2005), US 20050256164 A1 20051117

Applications 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid is a useful building block and has been used in the synthesis of the pesticide Cyclaniliprole.
References Liu, A.; et al.: Nongyao, 54, 790 (2015).

Applications 2-(2,4-Dichlorophenylamino)-4-trifluoromethylpyrimidine-5-carboxylic Acid is used to prepare a selective CB2 receptor agonist for the treatment of inflammatory pain.
References Giblin, G., et al.: J. Med. Chem., 50, 2597 (2007)

Applications 3-[4-(Acetyl)piperazin-1-yl]phenol is used in the preparation of fungicidal and bactericidal 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles and -1H-1,2,4-triazoles and their salts.
References Heeres, J., et al.: Ger. Offen. (1978), DE 2804096 A1 19780803

Applications 5-benzyl-1,3-oxazolidin-2-one (cas# 42746-49-6) is a useful research chemical.

Applications Used as a heterocyclic scaffold
References Matysiak, J., et al.: Bioorg. Med. Chem., 11, 2285 (2003), Das, J., et al.: Bioorg. Med. Chem. Lett., 18, 2652 (2008),

Applications Useful spin label for studying biological systems and polymers.
References Biochemistry, 33, 3855 (1994), J. Colloid Interface Sci., 165, 236 (1994)

Applications An intermediate for the synthesis of Alpidem.

Applications (S)-3-Hydroxypyrrolidin-2-one

Applications 5,6-Diamino-2-hydroxybenzimidazole (cas# 55621-49-3) is a compound useful in organic synthesis.

Applications A labelled impurity of Cefoperazone.
References Kitson, T., et al.: Biochem. J., 175, 83 (1978), Elenbaas, R., et al.: Clin. Pharmacol. Ther., 32, 347 (1982),

Applications 4,6-Dichloroimidazo[4,5-c]pyridine (cas# 2589-12-0) is a compound useful in organic synthesis.

Applications 2,6-Dimethyl-4-piperidinol is an isomer of 2,2-Dimethyl-4-piperidinol (D465900), an intermediate used to prepare diphenylpyraline derivatives with antimycobacterial activities.
References Weis, R., et al.: Eur. J. Med. Chem., 43, 872 (2008)

Applications 2,4-Dimethoxypyrimidine, is a versatile building block used in synthesis of various chemical compounds, such as derivatives of Cytidine (C998300).
References Kammerer, B., et al.: Anal. Biol. Chem., 382, 1017 (2005); Strong, L. and Matsunaga, H.: J. Surg. Oncol., 4, 528 (1972)

Applications Pentafluoropyridine (cas# 700-16-3) is a useful research chemical.

Applications 5-Bromo-2-aminopyrimidine (cas# 7752-82-1) is a compound useful in organic synthesis.
References Robins, M., et al.: J. Med. Chem., 50, 3897 (2007),

Applications (S)-tert-butyl 4-aminoazepane-1-carboxylate (cas# 878630-84-3) is a useful research chemical.

Applications Methyl 1-Methyl-1,2,3-triazole-5-carboxylate (cas# 105020-38-0) is used as a reagent in the composition and method for treating cognitive impairments in Down syndrome subjects.
References Potier, M. C., et al.: U.S. (2015) CODEN:USXXAM

Applications 3-[3-(aminomethyl)phenyl]-1,3-oxazolidin-2-one (cas# 952391-73-0) is a useful research chemical.

Applications 6-(4,6-Dioxo-1,4,5,6-tetrahydropyrimidin-2-yl-amino)hexanoicacidtrifluoroacetate (cas# 1185302-11-7) is a useful research chemical.

Applications 2-(pyrrolidin-1-yl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine dihydrochloride (cas# 1864058-89-8) is a useful research chemical.

Applications 1-Benzyl-4-butylpiperidine is an intermediate in the synthesis of AC 42 (A115600), an allosteric agonist of acetylcholine orthosteric site.
References Jacobson, M.A., et al: Mol. Pharmacol., 78, 648 (2010);

Applications 2-Piperazinone (cas# 5625-67-2) is a compound useful in organic synthesis.

Applications A chiral fluoro-pyridine derivative used in the preparation of dihydropyrrolopyrimidinone derivatives for use as MARK inhibitors.

Applications B-(2-Cyclopropyl-4-pyridinyl)-boronic Acid Hydrochloride, can be used in synthesis of isoindole carboxamides, pyrrolopyridine carboxamides, and similar compounds as inhibitors of phosphodiesterase type 10A for treating neurological and psychiatric disorders.
References Geneste, H., et al.: PCT Int. Appl. (2013), WO 2013000994 A1 20130103