Aliphatic compounds and derivatives

S05685 - 1,3-Diallyltetramethyldisiloxane

Applications 4-Methylindan is a shoyu flavouring that is used in soy sauce.
References Nunomura, N., et al.: Agri. Biol. Chem., 48, 1753 (1984);

2-Oxa-6-azaspiro[3.4]octane is an epidermal growth factor (EGF) inhibitor that has shown inhibitory activities against a number of different EGFR-related cell lines, including parental and mutant cell lines. This drug has been shown to inhibit the proliferation of cancer cells in vitro by binding to the epidermal growth receptor (EGFR). 2-Oxa-6-azaspiro[3.4]octane also inhibits the activity of tyrosine kinases and factor receptors, which are involved in the development of cancer cells. It is a potent inhibitor of TK1 and TK2 tyrosine kinases, and is more potent than piperazine or morpholine, which are other EGF inhibitors.

Sodium trifluoromethanesulfonate is an inorganic salt that is used as a reagent in organic synthesis. It is prepared by treating sodium metal with hydrogen fluoride and carbon disulfide. Sodium trifluoromethanesulfonate can be used to form stable complexes with copper(II) chloride, which are useful for the synthesis of organic compounds. This compound has been shown to undergo intermolecular hydrogen bonding interactions with glycol ethers, which are model systems for polymers. Sodium trifluoromethanesulfonate also has the ability to form hydrogen bonds with water molecules, which is important for its use in electrolytes. The structural analysis of sodium trifluoromethanesulfonate reveals that it contains one asymmetric center, which may be responsible for its ability to form hydrogen bonds.

12-(t-Boc-amino)-1-dodecanol is a versatile building block that is used in the synthesis of complex compounds. It can be used by itself or as a reagent or speciality chemical. This compound is useful for the synthesis of high quality research chemicals and useful scaffolds. 12-(t-Boc-amino)-1-dodecanol has CAS No. 67341-03-1 and is a fine chemical that has been widely used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.

Diazepam (also known as Valium) is a benzodiazepine drug used to treat anxiety disorders, muscle spasms, alcohol withdrawal symptoms, and other conditions. Diazepam is a tranquilizer that works by slowing down the activity of the central nervous system. It may also be used to control seizures, prevent certain types of muscle spasms, treat insomnia and relieve anxiety before surgery. Diazepam has been shown to have an affinity for nicotinic acetylcholine receptors in rat brains. This drug can work by blocking these receptors and preventing the transmission of impulses between neurons. Diazepam is marketed in many countries as an anxiolytic agent under trade names such as Valium and Librium. The clinical use of diazepam should be limited because it has been shown to cause birth defects in animal studies when given at high doses or during pregnancy.

1-Hexen-3-one is a carbonyl compound that has been shown to act as an estrogen receptor modulator. It has been isolated from the reaction product of hexene and formaldehyde, in which the intramolecular hydrogen is transferred to the carbon atom adjacent to the carbonyl group. 1-Hexen-3-one has been shown to induce muscle cell proliferation in vitro and inhibit liver microsomal protein synthesis in vivo. The 1-hexen-3-one can be prepared by reacting hexene with formaldehyde. The yield of this reaction is about 80%.
2 HCHO + C6H12 → C6H14O + 2 HCOOH

5-Bromo-1-pentene (5BP) is an antitumoral drug that has potent inhibitory activity against the t-cell leukemia cell line and other tumor cells. 5BP is an organoborane ester with a bromine atom at the 1-position. It is synthesized by reacting trifluoroacetic acid with a hydrohalic acid such as hydrochloric acid, or with a metal halide such as sodium carbonate, followed by reaction with dimethyl formamide and n-dimethylformamide. The 5BP molecule has a coordination geometry of octahedral and its structure consists of three hydrogen atoms, two methyl groups, one hydroxyl group, and one unsaturated alkyl group. The mechanism of action of 5BP is still unclear. The inhibition of protein synthesis may be due to the steric hindrance caused by the bulky bromine atom at the 1 position on the benzene ring.

M02569 - Tranilast