Building Blocks

7-Bromo-1-methylnaphthalene is a fluorescent dye that can be used to measure the concentration of DNA, RNA, and proteins. This compound is an intercalator, which means that it can bind to double stranded DNA or RNA near the center of the molecule where there is a space for binding. It has been used in the study of the thymic gland because it binds to DNA and RNA in cells from this organ. 7-Bromo-1-methylnaphthalene has also been used as a skeleton for organic compounds, such as dimethylammonium. The bromine atom in this compound can be replaced with other atoms like iodine or chlorine to make different colored dyes.

Versatile small molecule scaffold

2-Hydroxyethyl benzoate is a model system that has been used to study the mechanism of hydrolysis of an ester with a hydroxyl group. The reaction products are a metal hydroxide and a chloride ion. 2-Hydroxyethyl benzoate is an antimicrobial agent that has shown activity against bacteria, fungi, and protozoa. It is thought to work by reacting with fatty acids in the cell membrane, leading to disruption of the membrane and leakage of cellular contents. It also reacts with chloride ions to form hydroxybenzoic acid and water molecules. The activation energy for this reaction was found to be around 19 kJ mol−1.

3-Methoxythiophene-2-carbaldehyde is a ligand that has been shown to form a stable complex with potassium chloride. This compound is also reactive, and can be stabilized in the reaction vessel. In the presence of sulfate ions, 3-methoxythiophene-2-carbaldehyde will react to form a phosphotungstic acid precipitate. The dehydrated salt can be recrystallized by adding phosphotungstic acid, which stabilizes the product.

4-(2-Bromoethyl)morpholine hydrobromide is a solvent that is used as an agent in the production of other chemicals. It is a colorless, crystalline solid with a constant melting point of 130 to 131 degrees Celsius. 4-(2-Bromoethyl)morpholine hydrobromide is soluble in acetone, ethanol, ether, and water. This chemical has been shown to be toxic and should be handled with care.

Cabozantinib is a small molecule that is the first to target VEGFR-2, which is a receptor tyrosine kinase involved in the development of fibrosis. Cabozantinib inhibits the activity of VEGFR-2 by binding to its ATP-binding site and blocking the phosphorylation of downstream signaling pathways. Cabozantinib has been shown to have antifibrotic properties in both preclinical and clinical models. The drug candidate has been shown to reduce kidney fibrosis in animal models. The standard dose for cabozantinib was found to be 5 mg/kg, with a maximum tolerated dose of 20 mg/kg. In vitro studies have indicated that cabozantinib binds with high affinity to the ATP-binding pocket of VEGFR-2, exhibiting competitive inhibition against other kinases such as PDGFR-beta and cKit, as well as diaryliodonium (a specific inhibitor). Caboz

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,3-Dihydro-1H-pyrrolo[3,2-c]pyridine is an alkaloid compound that has various applications in research and chemical studies. It has been found to interact with dopamine receptors and exhibit photothermal properties. This compound has been studied in the context of G. lucidum (also known as Reishi mushroom) and its potential therapeutic effects. Additionally, it has shown interactions with quinpirole, lithium, ergovaline, efrotomycin, and other compounds. The photocatalytic and fatty acid properties of 2,3-Dihydro-1H-pyrrolo[3,2-c]pyridine make it a versatile compound for various research purposes.

Versatile small molecule scaffold

Versatile small molecule scaffold

Diethyl Acetylphosphonate is a synthetic chemical that is used in the production of ethyl esters, which are used as intermediates for the production of epoxides. It has shown to be a bidentate ligand and reacts with primary amines. Diethyl Acetylphosphonate can be made by reacting phosphorus pentachloride with ethyl acetate and hydrochloric acid. The reaction mechanism is similar to that of other organophosphorus compounds, in which a phosphine oxide intermediate reacts with an organic halide. Diethyl Acetylphosphonate has shown to be effective in detergent compositions and triethyl orthoformate, as well as alkanoic acid.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

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Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Tripropylphosphine is a fatty acid that can be synthesized by reacting tripropyl alcohol with phosphorus trichloride. Tripropylphosphine is soluble in organic solvents, and has an optical rotation of +58°. It has been shown to have cancer-inhibiting properties, as well as the ability to inhibit tumor growth and induce apoptosis in cancer cells. This compound may also be used as a growth regulator, since it inhibits the synthesis of certain proteins and enzymes.

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about N-(2-Methyl-6-benzoxazolyl)-2-propenamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.

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Versatile small molecule scaffold