Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Vanillic acid is a phenolic compound that can be found in vanilla and other plants. It is an important precursor for the synthesis of aromatic compounds such as ferulic acid, lignin, and coumarin. Vanillic acid has been shown to have a variety of biochemical and chemists properties, including the ability to aromatize, which means it can be used in the preparation of synthetic hormones. This compound also acts as an antioxidant by scavenging reactive oxygen species. Vanillic acid is found in two sources: pre-existing vanillin (from plants) and ferulic acid (from microbial metabolism). Vanillin is derived from coniferyl alcohol and coniferaldehyde, which are both found in poria. Ferulic acid is produced by polyporus fungi and can be converted into vanillic acid via decarboxylation.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Benzenesulfonyl)propan-2-ol is a chiral, neutral compound that is used as a heterofunctional catalyst. It is an electrophilic catalyst that can be used to catalyze hydroboration reactions. 1-(Benzenesulfonyl)propan-2-ol binds to the substrate with two bidentate interactions and participates in the reaction by donating electron density from the nitrogen atom of an allylic position. This compound is also capable of catalyzing catecholborane oxidation reactions, which are important for the synthesis of pharmaceuticals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenyl-1H-imidazole-4-carbaldehyde is an aldehyde that is used as a ligand in asymmetric synthesis. It can be used in the nitroaldol reaction to produce chiral imidazole derivatives. The compound is useful for the synthesis of molecules with high molecular weight and low reactivity, which can be further modified to produce pharmaceuticals. The compound has been shown to catalyze organic reactions, such as condensation products and stereospecific reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,2-dimethylpropanecarboximidate hydrochloride is a synthetic chemical that has been used as a reagent in organic synthesis. It was first developed in the early 1940s and was found to have hypotensive properties. The drug is a competitive inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase. Methyl 2,2-dimethylpropanecarboximidate hydrochloride is structurally related to benzimidazole derivatives and thiones. It has an aromatic heterocyclic structure with two nonpolar groups at opposite ends of the molecule.</p>

<p>Versatile small molecule scaffold</p>

<p>Cyclopentanecarboximidamide hydrochloride is a prodrug that is metabolized to its active form, pyridoxamine. The active form inhibits the enzyme histone deacetylase, which plays a role in viral infections. Cyclopentanecarboximidamide hydrochloride has been shown to be effective against chronic liver disease and other diseases of the central nervous system. The drug also has anti-inflammatory properties and may have antiviral effects. It also inhibits the production of inflammatory mediators such as nitric oxide and prostaglandin E2 by inhibiting cyclooxygenase activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Hexahydro-1H-pyrrolizine-7a-carbonitrile is an experimental drug that belongs to the class of medicines. It has a six-membered ring and is stable, with a molecular weight of 204. Hexahydro-1H-pyrrolizine-7a-carbonitrile has been shown to have antihistamine or anticholinergic properties, which may be due to its ability to inhibit the release of histamine from mast cells or block acetylcholine receptors in nerve endings. The mechanism for this action is unknown, but it may be related to the equilibrium between two diastereomers: one with an electron withdrawing group on nitrogen and another with electron donating groups on nitrogen. This equilibrium can be controlled by changes in temperature or pH levels.</p>

<p>4-N,4-N,6-Trimethylpyrimidine-2,4-diamine is a solvate of 4-N,4-N,6-trimethylpyrimidine and dimethyl sulfoxide. It has been characterized by X-ray diffraction analysis and the cocrystal structure with dimethyl sulfoxide. The crystal belongs to space group P2 1 2 1 2 1 2 1 . The chains are linked by hydrogen bonds. There are two hydroxy groups on the solvate molecule, as well as two cyano groups.</p>

<p>Versatile small molecule scaffold</p>

<p>8-Hydroxy-2-oxo-1,2-dihydroquinoline-5-carbaldehyde is a cyclic compound that has been identified as a metabolite of quinolones such as ciprofloxacin. It is also found in human urine and faeces. The structure of 8-hydroxy-2-oxo-1,2-dihydroquinoline 5'-carbaldehyde can be determined by spectrometric methods. This compound is the product of metabolism of ciprofloxacin and other quinolones. Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, leading to inhibition of RNA synthesis and protein synthesis. Quinolones are also metabolized to 8-hydroxy 2 -oxo 1,2 -dihydroquinoline 5'-carbaldehyde by glucuronic acid conjugation and hydrolysis. The</p>

<p>Versatile small molecule scaffold</p>

<p>4-Aminoquinoline-3-carboxylic acid is a linker that can be used to modify the structure of other molecules. It is used in the synthesis of dopamine conjugates, which are used as inhibitors for neurodegenerative diseases. 4-Aminoquinoline-3-carboxylic acid has been shown to inhibit dopamine uptake at nanomolar concentrations. These compounds have also been shown to inhibit the growth factor activity of nerve growth factor and brain derived neurotrophic factor.</p>

<p>1-Methylcyclopent-2-ene-1-carboxylic acid is a biodegradable, neutral compound that inhibits the activity of enzymes. It is used as a preservative in cosmetics and pharmaceuticals. This product is also used to prevent the formation of hippuric acid, which can be synthesized by the enzyme methyl esterification. 1-Methylcyclopent-2-ene-1-carboxylic acid is often used in conjunction with other organic acids such as citric or lactic acid to make them more effective.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Phenyl-1,3,4-oxadiazole-2-carboxamide (PDC) is a quaternary ammonium salt that has been shown to inhibit the growth of methicillin-resistant Staphylococcus aureus and other gram-negative bacteria. PDC inhibits the synthesis of proteins by binding to ribosomes in the bacterial cell wall. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for protein synthesis and cell division. PDC also has antimicrobial properties and can be used as an antibacterial agent.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydrazinoquinoline hydrochloride is a cation with a molecular weight of 176.2. It is cytotoxic and inhibits cancer cell growth. 4-Hydrazinoquinoline hydrochloride has been shown to be effective against lymphoid, breast, colon, and prostate cancer cells in vitro with IC50 values of 0.5 to 2 μM. This drug has been shown to bind to DNA by forming a Schiff base with the amine group of guanine residues in the DNA backbone. This binding leads to changes in DNA conformation that inhibit transcription and replication as well as protein synthesis and cell division.</p>

<p>4-(5-Formylfuran-2-yl)-N-methylbenzene-1-sulfonamide is a synthetic, antiparasitic and antibiotic drug that has been shown to possess antiviral and antifungal properties. It is an inhibitor of DNA synthesis and RNA transcription by blocking the enzyme RNA polymerase II, and also inhibits protein synthesis by inhibiting the enzyme ribosomal protein S12. 4-(5-Formylfuran-2-yl)-N-methylbenzene-1-sulfonamide is effective against both Gram positive and Gram negative bacteria, as well as yeast. The compound has been shown to be active against bacteria such as Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica serovar Typhi, Staphylococcus aureus (MRSA), Mycobacterium tuberculosis, Mycobacterium avium complex, Candida alb</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Chloro-8-nitroquinoline is an indian nitro compound that yields a greenish yellow liquid when reacted with quinaldine, which is an aromatic amino compound. The 8-nitroquinoline group in this compound has an amino group and reacts with the fungitoxicant guanidine. This class of compounds is used to control fungi such as Aspergillus and Myrothecium verrucaria. 6-Chloro-8-nitroquinoline can be hydrolyzed by strong acids or bases, yielding chloro formates.</p>

<p>4-(1H-1,2,3-Triazol-1-yl)phenol is a small molecule that has been shown to enhance the efficiency of diagnosing certain conditions. It can be used in microwells as a sensor for measuring the concentration of analytes such as antibodies, enzymes, proteins, and other compounds. This compound is immobilized on a solid surface and reacts with light to produce chemiluminescence. 4-(1H-1,2,3-Triazol-1-yl)phenol can be used as an immobilization agent for magnetic beads and also has fluorescent properties. It has been shown to inhibit hepatitis B virus replication by binding to the viral antigen. 4-(1H-1,2,3-Triazol-1-yl)phenol is also able to detect peroxide in biological fluids or luminol in animal tissue.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Isoguvacine is an alkaloid that belongs to the group of pharmacological agents. It has been shown to have a synergic effect with other drugs, such as 5-HT2 receptor antagonists and 5-HT3 receptor antagonists, at the level of the plate test. Isoguvacine inhibits the cyclase enzyme, which catalyzes the conversion of ATP into cAMP. The inhibition leads to a decrease in cAMP levels and consequently a decrease in intracellular calcium levels. This drug also blocks glutamate receptors on neurons, preventing their activation by glutamate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(3,5-Dichlorophenyl)propene is a dehydrating agent that is used in the production of pharmaceuticals, dyestuffs, and other chemicals. It can be used to produce chloride by the reaction with hydrogen chloride. 2-(3,5-Dichlorophenyl)propene can also be used to prepare oxalyl or tetrahydrofuran through dehydration reactions. This chemical is a reaction product of silicon and particle and can be used as a reaction system for the synthesis of thionyl chloride, which is an important reagent in organic chemistry.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Hydroxy-5-isopropyl-benzaldehyde is a chiral compound that can be used to synthesize various drugs. The synthesis starts with the reaction of the corresponding aldehyde with an appropriate base and a chiral ligand. The enantiomers of this compound are optically active, and the optical activity can be determined by using polarized light microscopy.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1,4-dihydroxycyclohexyl)acetic acid is a natural compound that has been shown to have neuroprotective and anti-cancer properties. It is used in clinical studies for the treatment of Alzheimer's disease and Parkinson's disease. This compound also has antioxidant properties that may be due to its ability to scavenge reactive oxygen species. 2-(1,4-Dihydroxycyclohexyl)acetic acid also has antibacterial activity against various bacteria including Escherichia coli, Staphylococcus aureus, Salmonella enterica serovar Typhimurium, and Listeria monocytogenes. The chemical composition of this compound includes two acetate groups and one cyclohexane ring. It is found in the fruit of Fructus Forsythiae and Forsythiae Herba.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Phenyl N-(3-aminophenyl)carbamate is a botanical drug that can be used to treat flu and fever. It has been shown to have a strong inhibitory effect on the influenza virus in vitro. Phenyl N-(3-aminophenyl)carbamate inhibits the replication of RNA and DNA, which may be due to its ability to bind with metal ions. Phenyl N-(3-aminophenyl)carbamate also has anti-inflammatory properties, which are due to its inhibition of prostaglandin synthesis. This drug is an effective corrosion inhibitor for steel pipes and other metal surfaces.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydroxy-pyridine-2,6-dicarboxylic acid diethyl ester is a multifunctional compound that can be used as an intermediate for the synthesis of a wide variety of organic compounds. It has been shown to be able to hydrolyze under acidic conditions to give ethoxycarbonyl groups, which are useful in organic chemistry. This compound also shows reactivity with dendrimers and other polymers, which can be used in various techniques. 4-Hydroxy-pyridine-2,6-dicarboxylic acid diethyl ester is also trifunctional and can be used as a coupling agent in reactions involving three different reagents. The multifunctionality of this compound makes it useful for many different applications.</p>

<p>2-(Aminomethyl)-5-hydroxy-4H-pyran-4-one is an amide that inhibits the uptake of dopamine and gamma-aminobutyric acid (GABA) by nerve cells in the brain. It has antinociceptive properties and has been shown to have antinociceptive effects in vivo. 2-(Aminomethyl)-5-hydroxy-4H-pyran-4-one binds to receptors for neurotransmitters, including GABA, dopamine, and acetylcholine. The amide also binds to fatty acids such as oleic acid and palmitic acid, which are important for cell membrane function. This drug can be used in conjunction with other drugs that act on GABA receptors, such as benzodiazepines or barbiturates.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>