Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Quinoline-5-carbonitrile is a cyanide compound that can be used in the synthesis of heterocyclic compounds. The reaction between quinoline and 5-cyanovaleric acid produces 6-nitroquinoline, which is then converted to dimethyl sulfoxide by alcoholysis. This reaction product can then be used to synthesize an amide or nucleophile. Quinoline-5-carbonitrile reacts with potassium in the presence of bifunctional hydrazide to produce a cyanide ion, which can be hydrolyzed by an acid to release hydrogen cyanide gas. This experiment has been shown as a model for reactions involving cyano compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-1,2,4-benzotriazine is an organic compound that is used as an anti-cancer agent. It is a cytotoxin that inhibits the growth of cells by binding to DNA. The Suzuki reaction was used to synthesize this compound in high yields. 3-Chloro-1,2,4-benzotriazine has potential anti-cancer activity and can be used in conjunction with other cytotoxic agents to treat cancer. This drug has been shown to have cytotoxic effects on tumor cells by inhibiting DNA synthesis and cell division.</p>

<p>Pyrazolo[1,5-a]pyridin-4-ol is a heteroaromatic compound that acts as an inhibitor of phosphodiesterase (PDE). It prevents the breakdown of cyclic nucleotides and thus leads to increased levels of cAMP and cGMP. Pyrazolo[1,5-a]pyridin-4-ol has been shown to have bronchodilatory activity in animal models. The drug also inhibits the production of inflammatory mediators such as prostaglandins by inhibiting cyclooxygenases. In addition, pyrazolo[1,5-a]pyridin-4-ol has been shown to be a potential PDE inhibitor replacement for the more commonly used PDE inhibitors such as sildenafil and tadalafil. However, due to its lack of stereochemistry and its bicyclic chemical structure, pyrazolo[1,5-a]</p>

<p>Versatile small molecule scaffold</p>

<p>1,4-Dimethyl 2-hydroxy-2-methylbutanedioate is an allylating agent that modifies the amino acid lysine residues in proteins. It has been shown to be effective in the treatment of skin lesions caused by Staphylococcus aureus and other bacteria because it inhibits bacterial growth through an antimicrobial effect. 1,4-Dimethyl 2-hydroxy-2-methylbutanedioate also has been used as a precursor for the synthesis of vitamin D3. This compound is metabolized in mammalian cells to form cysteamine, which is further converted to S-(1,4-dimethylpentadienoyl)cysteamine (DMPE). The resulting product can be used as a functional group on collagen or malic acid. 1,4-Dimethyl 2-hydroxy-2-methylbutanedioate also is used for modifications of mucocutaneous tissues such as skin and oral muc</p>

<p>Thienopyridine analogs are a class of chemical compounds that function as agonists of the receptor α. These compounds have been shown to inhibit fatty acid oxidation and ATP production in rat liver cells, which may be due to their ability to activate AMP-activated protein kinase (AMPK). Thienopyridine analogs are being investigated for use as anti-inflammatory agents and cancer treatments.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methylpropyl)cyclohexan-1-one is a heterobicyclic compound with a hydroxyl group and two cyclohexane rings. It has a nitrogen atom with three substituents, one of which is a trifluoromethyl group. This molecule is used as a polymerization initiator for polyester and polycarbonate production. It also can be used in the production of liquid crystal compositions, aliphatic hydrocarbons, and organic solvents. 2-(2-Methylpropyl)cyclohexan-1-one is an organic solvent that can be used in the preparation of monomers such as carbonyl groups or cyanates.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Tetrodotoxin is a potent neurotoxin that blocks the transfer of nerve impulses. It is used as a pharmacological treatment for diseases of the urinary tract such as bladder and urethral spasms, bladder dysfunction, and urinary retention. Tetrodotoxin can also be used for the treatment of other conditions that affect the target tissue such as stenosis or cavity. This drug has been shown to be beneficial in autoimmune diseases, inflammatory diseases, and infections. Tetrodotoxin is implanted into the body through devices such as catheters or balloons to treat these conditions. The drug has anticholinergic properties which may cause side effects like dry mouth, blurred vision, difficulty urinating, and dizziness.</p>

<p>Versatile small molecule scaffold</p>

<p>Tert-butyl (2S)-2-aminohexanoate is an intermediate that is used in the synthesis of glycine by the reaction of benzyl bromide and tert-butyl amine. The stereospecifically incorporated tert-butyl group has a high degree of enantioselectivity, which makes this intermediate useful in the synthesis of glycine. Tert-butyl (2S)-2-aminohexanoate can be synthesized using lithium diisopropylamide and a tertiary amine as an alkylating agent.</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>

<p>Versatile small molecule scaffold</p>