Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Bromo-4-cyclopentylbenzene (1-BCPB) is a chlorinated aromatic compound that can be synthesized by reacting 1-bromo-4-chlorobenzene and cyclopentylmagnesium bromide. The reaction sequence begins with the addition of hydrochloric acid to the first reactant, followed by magnesium chloride and ether. The mixture is heated to produce a liquid solution of ethylhexyloxy pyridine, which reacts with the second reactant in a sequence that leads to the desired product. 1-BCPB is used as an intermediate in organic synthesis. It has been shown to have moderate interaction with paraldehyde and pyridinium salts at room temperature, but it does not react with cycloalkyls or pyridinium salts at elevated temperatures.

Please enquire for more information about 4-Bromomethyl-4'-methyl-2,2'-bipyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Propylpyrazole is a non-classical inhibitor of aldehyde oxidase that has been shown to have an inhibitory effect on pentane. 1-Propylpyrazole has peroxidase-like activity, which means it can bind to lipid hydroperoxides in the presence of hydrogen peroxide or peroxidase. It has also been shown to be an effective inhibitor of dehydrogenase, which is an enzyme that catalyzes the oxidation of aldehydes and ketones to carboxylic acids. This drug is not active against classical aldehyde oxidases such as alcohol dehydrogenase, but it does inhibit polyunsaturated fatty acid synthesis by binding with cytochrome P450 enzymes.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

JMS-17-2 is a small molecule that was shown to have a potent and selective inhibitory effect on the production of chemokines in cancer cells. It blocks the interaction between CXCL12 and its receptor, CXCR4. This interaction is important for normal bone tissue development and function, as well as for chemotaxis and metastasis of cancer cells. JMS-17-2 has been shown to prevent tumor growth in animal models by inhibiting angiogenesis, or the formation of new blood vessels to supply nutrients to tumors. The drug also inhibits tumor growth by decreasing the number of primary tumors, reducing bone lesions, and inhibiting the progression of pancreatic cancer. Clinical trials are currently being conducted to assess the efficacy of JMS-17-2 in humans with advanced solid tumors.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Tetrahydroquinolin-2(1H)-one is a hydrobromide that has been found in the environment as an environmental pollutant. Tetrahydroquinolin-2(1H)-one is used to synthesize amides and has been studied by single-crystal x-ray diffraction. The molecule is centrosymmetric, with a molecular weight of 244.06 g/mol. Tetrahydroquinolin-2(1H)-one can be used as a ligand for metals such as chlorine and magnesium. It does not dissolve in water but does dissolve in organic solvents such as ethers, chloroform, or benzene.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Chloroisoquinolin-4-ol is a phenylpyrimidine with anti-inflammatory properties. It is used in the treatment of sensitivity and mediated diseases, such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. 1-Chloroisoquinolin-4-ol inhibits the enzymatic activity of matrix metalloproteinases (MMPs), which are enzymes that break down collagen and other proteins in the body. The inhibition of MMPs by 1-chloroisoquinolin-4-ol leads to reduced inflammation and pain. This compound is also an effective inhibitor of the activities of chloride channels involved in acid secretion by cells in the stomach lining, thus inhibiting acid production. 1-Chloroisoquinolin-4-ol has been shown to have anticholesterolemic effects on liver cells due to its ability to inhibit cholesterol synthesis through inhibition of HMG CoA

1-Bromo-2-(methoxymethyl)benzene is a boronic acid that is used in the synthesis of palladium complexes. It is synthesized by reacting 1-bromobenzene with methanol and methoxymethyl chloride. The 1-bromo-2-(methoxymethyl)benzene has been used as a ligand for palladium complexes, which are often used to catalyze organic reactions, such as the metathesis reaction. Synthetic methods have been developed to produce the compound and NMR spectra have been obtained to provide kinetic data on these reactions.

2-Bromobenzaldoxime is a biologically active molecule that has been shown to have significant physiological activities. It is an aldehyde, which is metabolized by the liver or kidneys into the corresponding alcohol, 2-bromoethanol. 2-Bromobenzaldoxime has been shown to be synthesized from diethyl ether and potassium phosphate in the presence of amino acids. The reaction proceeds with dehydration of the intermediate bromohydrin to form an aldoxime. This molecule can be used as a pharmaceutical drug for various diseases such as diabetes mellitus, hypertension, and inflammation.

1-Benzothiophene-5-carbonitrile is a heterocyclic compound that is formed by condensation of ethyl azidoacetate with indole under catalysis. It can be used in the synthesis of heterocycles. The yield of 1-benzothiophene-5-carbonitrile is about 56%.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Phenylbut-2-enoic acid is a prochiral, carbonyl compound that can be used in the synthesis of chiral pharmaceuticals. Mechanistic studies have shown that 3-phenylbut-2-enoic acid is a catalytic hydrogenation reagent that converts prochiral substrates to their corresponding chiral products. When combined with binap and butenoic acid, 3-phenylbut-2-enoic acid can catalyze the asymmetric synthesis of butenoate. The reaction yields high enantiomeric excesses and good yields.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Bromo-1-methylcyclohexane is a monomolecular gas that is used as an intermediate in organic synthesis. It reacts with halides to form cyclopentyl derivatives. This reaction has been shown to be faster than the corresponding reaction of 1-bromocyclohexane with chlorides or bromides. The rate of this reaction may be due to the polarizability and conformational changes of the molecule upon substitution by a methyl group. 1-Bromo-1-methylcyclohexane is also an ionizing reagent, which means it can cause electrophilic reactions to occur on other molecules. It has been found that the solvent effect on this product can affect its reactivity, with solvents such as water having more of an effect than solvents such as benzene. 1-Bromo-1-methylcyclohexane has been shown to interact with other compounds in both transfer and complex

Versatile small molecule scaffold

4-Amino-N-(4-methoxyphenyl)benzamide is a catalytic sulfamate that has been optimized for use in the synthesis of benzimidazole derivatives. 4-Amino-N-(4-methoxyphenyl)benzamide is used as a reagent for the preparation of aldehydes from sulfamic acid and various types of carboxylic acids. The reaction mechanism involves nucleophilic attack by the hydroxyl group from the sulfamate on the carbonyl carbon atom to form an intermediate, which then reacts with water to release hydrogen sulfate and form a new double bond.

1,2,3,4,5-Pentachlorobenzene is a chlorinated hydrocarbon that is used in the production of pesticides and herbicides. It is an ingredient in the manufacturing of pentachlorophenol and pentachloronitrobenzene. 1,2,3,4,5-Pentachlorobenzene has been used as a chemical intermediate or solvent for the production of other chemicals. The emissions from this chemical can be harmful to humans and animals because it has been shown to affect enzyme activities at sublethal doses. It also affects rat liver microsomes and causes DNA damage that can lead to cancer.

2,2-Dibromopropane is a synthetic chemical that has been used as a precursor in the production of nylon. It is an activator that can be used to form covalent bonds with reactive groups on other molecules. The activation energy for the reaction with piperazine is between 104 and 106 kJ/mol. 2,2-Dibromopropane undergoes acylation reactions under certain conditions, forming reaction products such as 2,2-dibromoethyl acetate and 2,2-dibromoethanol. The molecular weight of 2,2-dibromopropane is 192.19 g/mol and its structural formula is CHBrCHBrCHBrCHBrC≡C≡C≡C≡C≡C≡CC(O)OH.

1-Monotetranoin is a fatty ester that is involved in the process of lipolysis, which is the breakdown of fat cells. Lipolysis occurs when an enzyme called lipase hydrolyzes triglycerides into glycerol and three fatty acids. 1-Monotetranoin has been shown to be a potent stimulator of growth factor production and cell proliferation in vivo models. It has also been shown to be effective at inhibiting angiogenic processes in vitro, including the release of growth factors from fat cells. The neutral pH optimum for 1-monotetranoin is between 7 and 8, which may be due to its hydrophobic nature.

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

Versatile small molecule scaffold

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.