Building Blocks

Applications 6-Hydroxy-5-iodo-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid γ-Lactone is an intermediate in the synthesis of neuraminidase inhibitors.
References Kunstmann, M.P., et al.: J. Am. Chem. Soc., 84, 4115 (1962);

Applications trans-3-Hexenedioic Acid is used as a starting material in the synthesis of Adipic Acid (A291590) which is primarily used in the synthesis of nylon.
References Kim, Y. et al.: Ind. Eng. Chem. Res., 51, 15801 (2012); Li, C., et al.: Electrochim. Acta, 56, 1529 (2010)

Applications N-Hydroxy-1-oxy-nicotinamidine is an intermediate in the synthesis of rac-Arimoclomol Maleic Acid (A771275), which is a potential antidiabetic agent used for the treatment of insulin resistance.
References Kurthy, M., et al.: PCT Int. Appl. WO 2000050403 A1 20000831. Aug 31, 2000; Kuerthy, M., et al.: Hung. Pat. Appl. HU 2000000552 A2 20011228. Dec 28, 2001

Applications Isoquinoline n-oxide an isoquinoline metabolite.
References LaVoie, E. J., et al.: Carcinogenesis, 4, 1169 (1983)

Applications 2-Isopropylimidazole is a imidazole based compound, classified as a diazole and as an alkaloid. 2-Isopropylimidazole was investigated in animal studies as a new bone imaging agent.
References Wang, Y., et al.: Applied. Radiation. Isotopes., 69, 1169 (2011);

Applications Methyl 3-(4-chlorophenyl)-3-oxopropanoate (cas# 22027-53-8) is a useful research chemical.

Applications p-Chloroacetophenone is a chemical reagent used in the synthesis of various pharmaceutically and biologically active compounds such as COX-2 inhibitors.
References Penning, T. et al.: J. Med. CHem., 40, 1347 (1997); Wolfe, J. et al.: Angew. Chem. Int. Ed., 38, 2413 (1999);

Applications o-Isopropylaniline was used in the synthesis of a colorless amine-coordinated zinc complex.
References Li, D., et al.: Org. Biomol. Chem., 8, 1816 (2010)

Applications 3-​Chloroiodobenzene is used in the synthesis of is a common organic reagent used i the synthesis of a prostacyclin agonist actin in the treatment of pulmonary hypertension.
References Tran, T. et al.: J. Med. Chem., 60, 913 (2017);

Applications 4-Chloro-2-fluoroaniline is a compound used in the synthesis of 4-Chloro-2-fluoro-3-iodobenzenamine (1000590-87-3).

Applications Triamylamine(mixture of branched chain isomers) (CAS# 621-77-2) is a useful research chemical compound.

Applications 2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.
References Liu, J., et al.: Synthesis., 45, 943 (2013); Rambabu, D., et al.: Bioorg. Med. Chem. Lett., 23, 1351 (2013);

Applications 4-Chlorobutanoic acid methyl ester is used as a precursor chemical for projects such as vapor deposition for attaching ionic liquid to oxide surfaces1 and the synthesis of new thiopyran-​based heterocyclic systems2.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Xu, W., et al.: Angew. Chem. Int Ed., 56, 9072-9076. (2017)2. Palchykov, V.A., and al.: New J. Chem., 42, 1403 - 1412 (2018)

Applications 3-Iodobenzonitrile

Applications (R)-(-)-Carvone, is an antinociceptive monoterpene found as the main active constituent of essential oils obtained from plants of the genus Mentha. It is a novel agonist of TRPV1 channels. It can also be used as a chiral starting material.
References Goncalves, J.C., et al.: Cytometry part A., 83(2), 212 (2013); Liebigs ann., Chem., 403 (1993);

Applications 3-Methoxybenzenethiol is a versatile reactant used in the preparation of sulfides by cuprous iodide catalyzed coupling with aryl iodides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kwong, F., Buchwald, S.: Org. Lett., 4, 3517 (2002);

Applications An intermediate in the preparation of a potential inhibitor of GAR Tfase.
References Cheng, H. et al.: Bioorg. Med. Chem., 13, 3593 (2005)

Applications Intermediate in the preparation of Ertapenem (E635000).

Applications 4-Chloro-2,6-dimethoxypyrimidine (cas# 6320-15-6) is a compound useful in organic synthesis.

Applications Insecticidal activity.
References Durden, J. et al.; J. Agr. Food Chem. 17, 94 (1969)

Applications 8-Bromooctan-1-ol (cas# 50816-19-8) is a useful research chemical.

Applications p-Vinylguaiacol-d3 is the isotope labelled analog of p-Vinylguaiacol (V424960); an aromatic substance, one of the compounds responsible for the natural aroma of buckwheat, and also one of the major pyrolytic products of (E)-N-[(4-hydroxy-3-methoxy)-phenethyl]-3-[(3-methoxy-4-O-β-D-glucopyranosyloxy) phenyl] acrylamide; a new gycloside in tobacco.
References Janes, Damjan., et al.: Food Chem., 112(1), 120-124 (2009); Zhou, Rong., et al.: Yancao Keji, (7), 34-36, 42 (2013)

Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.
References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)

Applications 3-Methyl-2-buten-1-ol can be used as an additive to improve the antiknock properties of gasoline.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mack, J. Hunter, et al.: Fuel, 117(PB), 939-943 (2014)

Applications Butyric Anhydride is a chemical reagent used in the synthesis of amidoamine dendron-based co-adsorbents used in the improvement of dye-sensitized solar cells. Also used in the synthesis of allopurinol derivatives for their activity against Trypanosoma cruzi.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Xu, J. et al.: J. Mat. Chem. Mat. Energy Sust., 1, 14524 (2013); Raviolo, M. et al.: 69, 455 (2013);

Applications 2-Butynoic Acid is used as a reagent in the synthesis of BMS 911543 (B596075); a potent JAK2 inhibitor used as a potential treatment for myeloproliferative disorders. 2-Butynoic Acid is also used in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs as anti-cancer agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fitzgerald, M.A., et al.: J. Org. Chem., 80, 6001 (2015); Ramanivas, T., et al.: Eur. J. Med. Chem., 92, 608 (2015)

Applications 2-Thiophenecarbonyl Chloride is used in the synthesis of substituted pyridines as selective and highly effective GPR119 agonists. It is also seen in the preparation of diuretics.
References Wu, Y. et al.: Bioorg. Med. Chem. Lett., 20, 2577 (2010); Plattner, J. et al.: J. Med. Chem., 27, 1016 (1984)

Applications 6-Methylheptanol is a volatile compound used as flavor and fragrance agent.
References Benn, S., et al.: J. Agric. Food Chem., 44, 557 (1996), Pinal, L., et al.: Biotech. Let., 19, 45 (1997),

Applications (4-Fluorophenyl)hydrazine, HCl

Applications 3-(Chloromethyl)pyridine Hydrochloride has been used as a reactant for the synthesis of (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-one derivatives as Polo-like kinase 4 (PLK4) inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Laufer, R., et. al.: J. Med. Chem., 56, 6069 (2013)

Applications 1,4-Cyclohexanediol is used as a reagent in the development of noviomimetics as C-terminal Hsp90 inhibitors.
References Anyika, M., et al.: ACS Med. Chem. Lett., 7, 67 (2016)

Applications 6-Chloro-1-hexanol is used as a reagent in the synthesis of 3-(4-Chloro butyl)-1H-indole-5-carbonitrile; a key intermediate of the antidepressant drug Vilazodone (V265000).
References Anitha, N., et al.: Synthetic Commun., 44, 3563 (2014)

Applications 1,4-Cyclohexanedione, is a versatile building block in the synthesis of more complex compounds. This intermediate can be hydrolysed and decarboxylated to afford the desired dione.
References Nielsen. A.T., et al.: Org. Synth.,;Coll., 5, 288 (1973);

Applications 4-Nitrophenyl Phosphorodichloridate is used as a reagent in the synthesis of dihydrobenzodioxaphosphocine oxide derivatives which have antioxidant activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siva Prasad, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2016, ahead of print)

Applications 2-Fluorobenzaldehyde is a compound that has inhibitory effects on the activity of mushroom tyrosinase, a copper-containing enzyme that is widely used in a number of applications such as direct protein-protein cross linking, and activating tyrosine residues in polypeptides for protein cross-linking to chitosan films.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Halaouli, S., et al.: J. Appl. Microbiol., 100, 219 (2006); Huang, X., et al.: J. Enzyme Inhib. Med. Chem., 21, 413 (2006); Sung-Yum, S., et al.: J. Agric. Food Chem., 51, 2837 (2003);

Applications 2-Nitro-4,5-methylenedioxybenzaldehyde (cas# 712-97-0) is a compound useful in organic synthesis.
References Kajihara, Y., et al.: Carb. Res., 331, 455 (2001)

Applications 5-Nitroisoquinoline (cas# 607-32-9) is a compound useful in organic synthesis.

Applications 3-Methoxypropionitrile (cas# 110-67-8) is a useful research chemical.

Applications 4-(Chloromethyl)benzoyl Chloride is used in the synthetic preparation of various compounds and pharmaceuticals. 4-(Chloromethyl)benzoyl Chloride was used in the synthesis of several imidazo[2,1-b]thiazoles.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bratulescu, G., et al.: Asian. J. Chem., 24, 350 (2012);

Applications 2-(Cyclopropylmethoxy-d4)-acetic Acid (cas# 1346602-05-8) is a compound useful in organic synthesis.

Applications 2-Benzylaniline was used to study efficient and convenient heterogeneous palladium-catalyzed regioselective deuteration at the benzylic position.
References Kurita, T., et al.: Chem. Eur. J., 14, 664 (2008);

Applications tert-Butyl Perbenzoate is used as a catalyst in the preparation of paper strengthening agents for papermaking.
References Xuan. S., et al.: Faming Zhuanli Shenqing. 6pp. (2020)

Applications 2-(Cyclopropylmethoxy)-acetic Acid (cas# 246869-08-9) is a compound useful in organic synthesis.

Applications 1,3-Benzothiazole-4-sulfonyl Chloride (cas# 149575-65-5) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Nitrobenzonitrile-d4 (CAS# 1219798-46-5) is a useful isotopically labeled research compound.

Applications 4-Nitrobenzonitrile (cas# 619-72-7) is a useful research chemical.

Applications is a building block used in various chemial synthesis such in the preparation of 6-(carboxymethylureido)-(±)-nicotine (CMUNic), nicotine immunogen, and  imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione.
References Y Hieda et. al,: The Journal of pharmacology and experimental therapeutics, 283(3), undefined (1998-2-12); Papadopoulos EP.Journal of Heterocyclic Chemistry 18(3), 515-518,

Applications An impurity of Atorvastatin.
References Graul, A., et al.: Drugs Fut. 22, 956 (1997),

Applications Ethyl 3-benzoylacrylate is an impurity of Enalapril (E555250), an antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor.
References Gross, M., et al.: J. Pharmacol. Exp. Ther., 216, 552 (1980), Gomez, H.J., et al.: J. Cardiovasc. Pharmacol., 15, Suppl. 3, S26-S29, (1990), MacFadyen, J., et al.: Clin. Pharmacokinet., 25, 274 (1993), Malini, P.L.: Adv. Ther., 10, 253 (1993),

Applications 4-Methoxy-3-nitrobenzoic acid is a substituted nitrobenzoic acid reagent for proteomics and organic synthesis research.
References Achary, R. et al.: Bioorg. Med. Chem. Lett., 27, 2185 (2017);

Applications 1-(Benzyloxy)propan-2-one (cas# 22539-93-1) is a useful research chemical.

Applications 2-chloro-1-(4-chlorophenyl)ethanone (cas# 937-20-2) is a useful research chemical.

Applications Methyl 4-Methoxyphenylacetate (cas# 23786-14-3) is a useful research chemical.

Applications 3-Chlorophenylboronic acid is a useful research chemical, a useful reagent for Suzuki-Miyaura cross-coupling reactions.
References Savitha, B., et al.: J. Heterocycl. Chem., 55, 2277 (2018); Liu, K., et al.: Eur. J. Org. Chem., 34, 4769 (2018)

Applications Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors.
References Dufer, M. et al.: Biochem. J. et al.: 15, 368 (2002); Andres, J. et al.: Bioorg. Med. Chem. Lett., 23, 785 (2013);

Stability Moisture Sensitive
Applications Propylphosphonic Anhydride is used to prepare aryloxybenzylmorpholines as dual serotonin and noradrenaline reuptake inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fish, P., et al.: Bioorg. Med. Chem. Lett., 18, 2562 (2008)

Applications (E)-2-Pentenal, is a flavor volatile found in tomato, virgin olive oil and sardine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1-Heptyne can be used for cycloisomerization of alkynyl imines and alkynylation of oxiranes.
References Kel’in, A. V., et al.: J. Am. Chem. Soc. 123, 2074 (2001); Yamaguichi, M., et al.: Tetrahedron Lett. 24, 391 (1983)

Applications Glyoxal Sodium Bisulfite (contains oligomers) (cas# 517-21-5) is a useful research chemical.

Applications Hexanoic Anhydride, is used as a reactant in the total synthesis of acremomannolipin A via steroselective β-mannosylation of 4,6,-O-benzylidene-protected mannosyl sulfoxide with a D-mannitol derivative.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tsutsui, N., et al.: Tetrahedron Lett. 54, 451(2013)

Applications 2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid-d3 (cas# 1346604-53-2) is a compound useful in organic synthesis.

Applications 2-Amino-5-bromo-4,6-dimethylpyridine (cas# 89856-44-0) is a compound useful in organic synthesis.

Applications Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.
References Keul, H., et. al.: Macromol. S., 19, 1 (1971)

Applications 2-​Amino-​6-​methylpyridine is a reagent used in the identification of selective inhibitor for phosphatidylinositol 3-kinase (PI3Kα).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Miller, M. S., et al.: Bioorg. Med. Chem., 25, 1481-1486 (2017);

Applications 3-(Aminomethyl)pyridine is a compound useful in organic synthesis. A pyridine derivative with vasodilating activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Uno, B. E., et al.: Adv. Syn. Catal., 360, 1719 (2018); Trcka, V., et al.: Pharmazie, 11, 242 (1956)

Applications Pyridine hydrobromide (cas# 18820-82-1) is a useful research chemical.

Applications 1,6-Dibromohexane is used as a reagent in the synthesis of novel benzo[b]xanthone derivatives which have potential antitumor activity. It is also used as a cross-linker for the cross-linking of glycuronans.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Luo, L., et al.: J. Serb. Chem. Soc., 78, 1301 (2013); Matricardi, P., et al.: Carbohyd. Polym., 27, 215 (1995)

Stability Hygroscopic
Applications Biogenic polyamine formed from spermidine and occurring in almost all tissues. Essential for both normal and neoplastic tissue growth. Involved in the modulation of calcium-dependent immune processes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Israel, et al.: J. Med. Chem., 7, 710 (1964), Janne, J., et al.: Biochim. Biophys. Acta, 473, 241 (1978). Theoharides, T.C., et al.: Life Sci., 27, 703 (1980), Horn, Y., et al.: Cancer Res., 42, 3248 (1982),

Applications This compound has been shown to inhibit iodothyronine 5’-deiodinase, the enzyme responsible for the 5’-deiodination of thyroxine in human liver cells.
References Harbottle, R., et al.: Biochem. J., 217, 485 (1984),