Building Blocks

Applications 9α-Hydroxy 1,2-Dihydro Betamethasone 17,21-Dipropionate is a compound useful in organic synthesis.

Applications Intermediate in the production of Isosafrole and Ethylone.
References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),

Applications Hexadecanoic-13,13-d2 Acid (CAS# 62690-28-2) is a useful isotopically labeled research compound.

Applications 2-Ethoxyethanol-1,1,2,2-d4 (CAS# 1219805-07-8) is a useful isotopically labeled research compound.

Applications 2'-Hydroxypropiophenone (cas# 610-99-1) is a useful research chemical.

Applications 3,4-(Methylenedioxy)phenylacetic Acid (cas# 2861-28-1) is a compound useful in organic synthesis.
References Perez-Medrano, A., et al.: J. Med. Chem., 52, 3366 (2009), Moon, J., et al.: Bioorg. Med. Chem. Lett., 20, 734 (2010),

Applications 1-Chlorohexane-d13 (CAS# 1219798-45-4) is a useful isotopically labeled research compound.

Applications 4-Methoxybenzoic-2,3,5,6-d4 Acid (CAS# 152404-46-1) is a useful isotopically labeled research compound.

Applications Hexadecanoic-11,11,12,12-d4 Acid (CAS# 75736-57-1) is a useful isotopically labeled research compound.

Applications Propazine-d14 (di-iso-propyl-d14) (CAS# 1219802-87-5) is a useful isotopically labeled research compound.

Applications 2-(quinolin-4-yl)ethan-1-amine (cas# 860720-12-3) is a useful research chemical.

Stability Hygroscopic
Applications 3-Bromo-1-(trimethylsilyl)-1-propyne is a reactant used in the preparation of a novel lipid mediator with anti-inflammatory activity. Also used in the preparation of (+)-Rubriflordilactone A, a natural nortriterpenoid.
References Goto, T. et al.: Tetrahedron., 71, 8320 (2015); Goh, S. et al.: Angew. Chem. Int. Ed., 54, 12618 (2015);

Applications 4-Methoxybenzaldehyde-alpha-d1 (CAS# 19486-71-6) is a useful isotopically labeled research compound.

Applications 2-Isopropoxy-2-phenylacetic acid

Applications A Cortisol metabolite.
References Grillitsch, B. et al.: Environ. Toxicol. Chem. 29, 1613 (2010)

Applications (Bromomethyl)cyclohexane is a reagent that is used in the synthesis of cyano thiouracils as SecA inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chaudhary, A. S., et al.: Bioorg. Med. Chem., 23, 105 (2015);

Applications 2-Methylcoumaran is an impurity formed during the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor.

Applications 4-Hydroxychlorpropham is an intermediate in synthesizing 4-Hydroxychlorpropham Sulfate Sodium Salt (H825075), which is a chemical herbicide used in the protection of crops. It also maintains the ability to induce mitochondrial dysfunction in rat hepatocytes.
References EPA.: Fed. Reg., 72, 37646 (2007); Nakagawa, Y. et al.: Toxicol., 200, 123 (2004);

Applications Bromosuccinic acid is prepared from Succinic acid (S688765), an important precursor in many chemicals used in the food, chemical and pharmaceutical fields. Bromosuccinic acid is also used as a reagent to prepare L-Hydrazinosuccinic acid.
References Gutowsky, H., et al.: J. Chem. Phys., 31, 1278 (2004); Song, H. & Lee, S.: Enzyme Microb. Tech., 39, 352 (2006); Yamada, R., et al.: BBA-Prot. Struc. Mol. Enzym., 831, 82 (1985)

Applications Hexadecanoic-3,3-d2 Acid (CAS# 83293-32-7) is a useful isotopically labeled research compound.

Applications 4-Methylcatechol-d8 (CAS# 1219803-18-5) is a useful isotopically labeled research compound.

Applications Reagent used in the preparation of pharmaceutically active Dibenzocyclohenptenes.

Applications (±)-1,2-Propylene-3,3,3-d3 Oxide (CAS# 2245-32-1) is a useful isotopically labeled research compound.

Applications A thiozole derivative that is converted to L-cysteine by the enzyme 2-amino-Δ2-thiazoline-4-carboxylic acid hydrolase (ATCase) upon induction by S-compounds in certain bacteria.
References Tamura, Y. et al.: J. Gen. Appl. Microbiol., 47, 193 (2001); Shiba, T. et al.: J. Gen. Appl. Microbiol., 68, 2179 (2002);

Applications 2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Montzka, T.A., et al.: Tetrahedron Lett., 15, 1325 (1974); Kono, M., et al.: Bioorg. Med. Chem., 22, 1468 (2014); Gillespie, P., et al.: Bioorg. Med. Chem. Lett., 24, 949 (2014)

Applications 1,2-Dimethoxybenzene-4,5-d2 (CAS# 203645-56-1) is a useful isotopically labeled research compound.

Applications 5-Methyl-1,3-cyclohexanedione has been used in the synthesis of racemic (±)-fawcettimine and 3,6-dimethyl-2-phenylsulfanyl-3,5,6,7-tetrahydro-2H-benzofuran-4-one.
References Xin, L., et al.: Angewandte Chemie (International Edition), 46, 7671 (2007); Lee, Y., et al.: Korean Chem. Soc., 23, 1477 (2002)

Applications 2-Bromo-5-iodobenzoic acid

Applications trans-Ethylene-1,2-d2 (Low Enrichment) is a useful isotopically labeled compound of Ethylene (E546215)

Applications Ethyl-n-methyl malonamide

Applications 1-Bromo-3-iodobenzene is a useful compound for preparing an organic light-emitting device.
References Park, S. U., et al.: Repub. Korea (2020), KR 2176164 B1

Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Aminobenzeneboronic acid pinacol ester is a reagent used to synthesize regiospecific quinolines. It can also be used to synthesize (±)-Epimeloscine and (±)-Meloscine.
References Zhang, H., et al.: J. Am. Chem. Soc. 133, 10376 (2011); Horn, J., et al.: Org. Lett 10, 4117 (2008)

Applications (±)-Tetrahydro-2-furoic-d7 Acid (CAS# 1219798-42-1) is a useful isotopically labeled research compound.

Applications Isoxazolo[5,4-b]pyridin-3-amine
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications (3-Bromopropoxy)-tert-butyldimethylsilane is a reagent in the preparation of piperidinylcarbonyl sulfamates as a novel class of antihyperlipidemic agents with LDL-receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia.
References Asano, S., et al.: J. Med. Chem., 53, 3284 (2010)

Applications 1,5-Dinitronaphthalene-d6 (CAS# 1219804-48-4) is a useful isotopically labeled research compound.

Applications Hexadecanoic-9,9-d2 Acid (CAS# 272442-14-5) is a useful isotopically labeled research compound.

Applications 3-Methylcrotonic acid is used as a starting material to synthesize 3-Methylcrotonyl-CoA, an intermediate in the metabolism of Leucine.
References Anderson, M., et al.: Plant Physiol., 118, 1127 (1998); Hector, M., et al.: Biochemistry, 15, 3465 (1976)

Applications 1-Dodecane-d25-thiol (CAS# 869563-00-8) is a useful isotopically labeled research compound.

Stability Light Sensitive
Applications 5-Amino-3-methylpyrazole (cas# 31230-17-8) is a compound useful in organic synthesis.

Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.

Applications 3-Amino-2-methyl-2-propanol, is a versatile intermediate used for the synthesis of more complex compounds, including inhibitors. It is an intermediate in the preparation of metabolites of Darunavir (D193500), such as (A581405).
References Debouck, C., et al.: Drug Dev. Res., 21, 1 (1990), Krohn, A., et al.: J. Med. Chem., 34, 3340 (1991), Vazquez, M., et al.: J. Med. Chem., 38, 581 (1995),

Applications 2-Thiopheneethanol is a thiophene derivative used in the preparation of oligothiophene isothiocyanates as fluorescent markers for biopolymers. 2-Thiopheneethanol is also used in the preparation of other biologically active compounds such as the analgesic Sulfentanyl and the antithrombotic Clopidogrel Hydrogen Sulfate (C587250).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Barbarella, G. et al.: J. Am. Chem. Soc., 123, 11600 (2001); Yang, Z.: Yiy. Gong., 16, 241 (1985); Lin, Z. et al.: Ship. Yu Yao., 12, 235 (2010):

Applications A component of alkyl sulfobetaine-type detergents.
References Bailyes, E., et al.: Biochem. J., 203, 245 (1982), Wetzler, L., et al.: J. Exp. Med., 168, 1883 (1988), Haeuw, J., et al.: Dev. Biol., 103, 245 (2000), Kramer, R., et al.: Eur. J. Biochem., 267, 885 (2000), Beck, A., et al.: Biologicals, 29, 293 (2001),

Applications 6-hydroxyquinoline-2-carboxylic acid (cas# 75434-18-3) is a useful research chemical.

Applications 4-Hydroxypyridine, is a building block used in various chemical synthesis. It is used for the synthesis of bicyclic pyridinol analogues acting as antioxidants and capable of preserving mitochondrial function.
References Xiaoqing, X. C., et al.: Bioorg. Med. Chem., 20 (11), 3584 (2012);

Applications 1-Chlorohexadecane-d33 (CAS# 352431-13-1) is a useful isotopically labeled research compound.

Applications 4-Dodecylbenzenesulfonic acid
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Methylcyclohexanemethanol is patented for use as an ingridient of air fresheners. It can also be used to synthesize thiazolidinedione (2,4-thiazolidinedione, T344250) derivatives as 15-PGDH inhibitors.
References Wu, Y., et al.: Bioorg. Med. Chem., 18, 1428 (2010);

Applications 1,12-Dodecanedioic-2,2,11,11-d4 Acid (CAS# 97543-02-7) is a useful isotopically labeled research compound.

Applications 3,5-DINITRO-4-HYDROXYBENZOIC ACID (cas# 1019-52-9) is a useful research chemical.

Applications Reagent used in the synthesis of Imidazole derivatives.
References Prasad, J., et al.: Bioorg. Med. Chem., 6, 1707 (1998),

Applications Diquat-d12 Dibromide is a useful isotopically labeled compound

Applications Methyl 2-Bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
References Gangloff, A et al.: Bioorg. Med. Chem. Lett., 23, 4501 (2013); Zhao, G. et al.: Bioorg. Med. Chem. Lett., 23, 3914 (2013);

Applications Hexadecanoic-7,7,8,8-d4 Acid (CAS# 75736-49-1) is a useful isotopically labeled research compound.

Applications Hydroxypropyl Chitosan is an antibacterial used to make organic rectorite-based nanofibrous mats with bacterial inhibition. Hydroxypropyl Chitosanhas been shown to exhibit inhibitory effects on the levels of Fe, Zn and Ca in liver, heart, lung, spleen, kidney and femur at high dosages in mice.
References Deng, H., et. al.: J. Biotma. Sci-Polym. E., 24, 485 (2013); Wang, Z., et. al.: Int. J. Biol. Macromol., 64, 25 (2014);

Applications Hexadecanoic Acid-1,2-13C2 (CAS# 86683-25-2) is a useful isotopically labeled research compound.

Applications N,N-Dimethyl-d3-glycine HCl (N-methyl-d3) (CAS# 1219795-14-8) is a useful isotopically labeled research compound.

Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.

Applications 4-Chloro-1-butanol is a reagent used in the preparation of pharmaceutical compounds such as canthine analogues for their activity against HeLa cervical cells. Also used in the preparation of novel and highly potent Bryostatin, another anti-cancer agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Naik, P. et al.: Tetrahedron, 69, 6545 (2013); Wender, P. et al.: J. Am. Chem. Soc., 124,13648 (2002);

Applications Trifluorothymine is an antitumor and antiviral agent. Trifluorothymine was found in patients’ urine as a metabolite of Trifluorothymidine as cancer treatment.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cirak, C., et al.: J. Mol. Model., 18, 4453 (2012); Dexter, D., et al.: Cancer Res., 32, 247 (1972)

Applications p-Hydroxypropiophenone is a 4-hydroxyphenyl ketone used in the preparation of potential antitumor agents. p-Hydroxypropiophenone is a lignin degrradation product.
References Masselter, S. et al.: Chromatographia, 40, 51 (1995); Andreani, A. et al.: Arch. Pharm., 317, 583 (1984);

Applications An aromatic intermediate compound useful for the preparation of substituted melamine, ammelides, and ammelines.
References Sunaga, S., Bioorg. Med. Chem., 14, 4217 (2006),

Applications L-Glutamic Acid γ-p-Nitroanilide is a substrate for γ-glutamyltransferase (GGT), which is an important enzyme with wide applications in biocatalysis and clinical diagnosis.
References Li, Zh., et al.: J. Zh. Univer. Sci., 12, 180 (2011); Qin, D., et al.: Huagong Xuebao , 62, 378 (2011);

Applications 1-Bromo-2,3-dimethyl-benzene is a useful synthetic intermediate. It is used as a reagent to synthesize vaniprevir. It can also be used to synthesize various piperidine derivatives, e.g., 4-arylpiperidines and cinnamoylpiperidine, which are 5-HT2C agonist and PAR1 antagonist, respectively.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Song, Z., et a;.: J. Org. Chem., 76, 9553 (2011); Conway, R., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012); Planty, B., et al.: Bioorg. Med. Chem. Lett., 20, 1735 (2010)

Applications (2-Ethynylphenyl)boronic acid