Building Blocks

<p>6-Acetyl-1,2,3,4-tetrahydropyrimidine-2,4-dione is a chemical compound that has two functions. One function is as a dianion that can be used to measure the hydrogen ion concentration in an aqueous solution with the pH range of 1 to 14. The second function is as an acid complex with constant K1 and K2 values. This compound is stable in the presence of acids and bases and can react with alcohols to form esters. 6-Acetyl-1,2,3,4-tetrahydropyrimidine-2,4-dione has been used in the synthesis of orotic acid from orotic acid esters.</p>

<p>1-Benzoylpyrrolidine-2,5-dione is a ketone that can be used as an industrial coupling agent. It is used in the synthesis of saccharin and arylketones. This reagent can be used to cleave amides and succinimide esters. 1-Benzoylpyrrolidine-2,5-dione reacts with arylsiloxanes to form functional groups on the silicon atom. In addition, this compound can be used as a substrate for organic synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>2-[2-(Hydroxymethyl)phenyl]ethan-1-ol is an antibacterial agent that belongs to the group of aryl alcohols. It is a bactericidal agent that inhibits the growth and reproduction of bacteria by binding to their DNA. 2-[2-(Hydroxymethyl)phenyl]ethan-1-ol has shown effectiveness against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae and Bacillus subtilis. This compound has also been shown to be active against Mycobacterium tuberculosis, but not against Candida albicans or Aspergillus niger.</p>

<p>2-Amino-3,4,6-trichlorophenol is a versatile compound that has various applications in different fields. It is commonly used in chromatographic analysis as a reference standard and as a reagent in organic synthesis. This compound is also found naturally in plants such as monoterpenoids, isoflavones, pyrazoles, alkaloids, and chalcones. Additionally, it has been identified as a component of certain research chemicals.</p>

<p>4-Chloro-2,5-dimethoxyaniline (4CMA) is a synthetic organic compound that can be used in the synthesis of dyes and pharmaceuticals. This compound is synthesized by reacting ammonium nitrate with 4-chloro-2,5-dimethoxybenzene in the presence of sodium formate. The reaction takes place in an organic solvent such as xylene or sulfoxide. The product is then reacted with methyl alcohol and alkylation agent such as hydrogen chloride to produce the desired product.</p>

<p>Ethyl 3-cyano-3-phenylpyruvate is a chemical compound that is used as an antiviral agent. It has been shown in vitro to inhibit influenza virus and depression. Ethyl 3-cyano-3-phenylpyruvate is synthesized by the alkylation of furyl with phenyl group, followed by the reduction of the tetronic acid formed. The antiviral activity of ethyl 3-cyano-3-phenylpyruvate was analyzed by assessing the ability to inhibit viral replication and production of new viruses. The sodium salt form of this compound is used in foodstuff as a preservative.</p>

<p>Sodium 5-sulphoisophthalate is a chemical compound that is the monosodium salt of sulfonated 5-sulphoisophthalic acid. It is an important raw material in the production of polycarboxylic acids, which are used as intermediates in the production of nylon and polyester. The reaction vessel for the production of sodium 5-sulfoisophthalate is usually a stainless steel pressure reactor. Sodium carbonate and sulfur trioxide react at high temperatures to produce sodium 5-sulfoisophthalate and hydrogen sulfide. The product can be purified by fractional distillation, or it can be reacted with ammonia to form ammonium sulfite, which can then be used as a fertilizer. Sodium 5-sulfoisophthalate has been shown to have fluorescence properties and can serve as a probe for hydrogen bonding between molecules.</p>

<p>(2S)-2-Acetamido-3-hydroxy-N-methylpropanamide is a compound that belongs to the class of phosphopeptides. It is synthesized by reacting an N-acetylcysteamine with methylamine in the presence of sodium bicarbonate. This compound has shown to have antihypertensive and vasodilatory effects, as well as the ability to inhibit platelet aggregation.</p>

<p>Tert-butyl 2-azidoacetate is a synthetic chemical that is used to synthesize azides. It reacts with ethyl diazoacetate to produce tert-butyl azide and tert-butanol. This reaction can be used to synthesize the azide functional group in a single step, which is more efficient than the traditional two-step process. Tert-butyl 2-azidoacetate has been shown to have antibacterial activity against hl-60 cells, an immortalized promyelocytic leukemia cell line. The antibacterial effect of tert-butyl 2-azidoacetate may be due to its ability to react with amino groups on proteins and phosphonates on DNA, which are important for bacterial growth and replication.</p>

Versatile small molecule scaffold

<p>2-Hydroxy-4,6-dimethylbenzoic acid (HMBA) is a tumor treatment drug that can be used in combination with other drugs. HMBA inhibits proton pumps and the synthesis of DNA, RNA, and protein. The proton pump inhibitors are used to treat acid reflux disease, ulcers, and gastroesophageal reflux disease. HMBA has been shown to significantly inhibit tumor growth in animal studies. This drug also has anti-inflammatory effects and may be useful for treating arthritis.</p>

<p>Versatile small molecule scaffold</p>

<p>Acetaminophen, also known as paracetamol, is a widely used drug for pain relief and fever reduction. It is metabolized by the liver, mainly through the cytochrome P450 pathway. The cytochrome P450 pathway produces reactive intermediates that can cause oxidative stress and DNA damage. Acetaminophen has been shown to be toxic to rat primary hepatocytes in vitro at concentrations of 40-160 μM after 24 hours. Acetaminophen has also been shown to be mutagenic and carcinogenic in rats at doses of 5000 mg/kg/day, which is equivalent to a human dose of 160 mg/kg/day or higher. These effects are due to acetaminophen’s metabolic activation by reactive oxygen species (ROS) and its ability to induce cytotoxicity and oxidative stress in cells.</p>

<p>2'-Hydroxy-5'-methylacetanilide (HMA) is a methemoglobin-inducing agent that is used to study the uptake of acetylated compounds. HMA has been shown to have dose-dependent effects on methemoglobin production and can be used to study the interaction of active substances with hemoglobin. HMA is also used in preloaded doses as an antidote for exposure to nitrobenzene or phenacetin. This drug also induces monomers, which are small molecules that contain one or more acetyl groups, and suppresses the efflux of substances from cells. 2'-Hydroxy-5'-methylacetanilide is also known as acetoxybenzoic acid and has been shown to inhibit synaptic activity in rats.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Chloromethyl)-1-methoxy-2-nitrobenzene is a heterocyclic compound that belongs to the group of germicides. It is prepared by the reaction of potassium carbonate with methylamine and 4-chloro-1-methoxybenzene. The chloromethyl group in this compound can be replaced by other halogens, such as bromine or iodine, in order to produce other derivatives. This type of chemical has been used in the past as a fungicide, but is now mostly used as a precursor for dyes. 4-(Chloromethyl)-1-methoxy-2-nitrobenzene has an analogous reaction with amines, which are compounds containing nitrogen and hydrogen atoms that have one or more organic substituents. These reactions are useful for producing drugs such as amphetamines, barbiturates, and some types of antibiotics.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Nitrophenyl)oxirane is an organic compound that is used as a reactant in organic chemistry. It has been shown to be an effective anti-inflammatory agent in vitro. This compound reacts with the hydroxyl group of epoxyethane to form a stable oxirane, which can then be oxidized by hydrogen peroxide to form an epoxide. The enantiomeric purity of 2-(4-nitrophenyl)oxirane was determined using an asymmetric synthesis and found to be greater than 99%.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-oxohexanoate is a synthetic chemical that is used as a solvent in organic synthesis. It can be deuterated to produce a deuterated derivative, which has been shown to have improved stability in an organic environment. Methyl 2-oxohexanoate has been used as the starting material for the asymmetric synthesis of some medicinal drugs, including the anti-inflammatory drug piroxicam. This chemical also has been shown to have anticancer activity due to its ability to inhibit fatty acid synthase and nutrient uptake in pancreatic cancer cells.</p>

<p>2-(Isopropylthio)aniline is a synthetic chemical compound. It is a primary alkyl amine, with the chemical formula CH3CH2NHCH2CH2SCH3. It has two alkyl groups, one substituent and one trifluoroacetic acid group. 2-(Isopropylthio)aniline is synthesized in the laboratory by reacting benzene with an aminophenyl group and an alkyl group. The reaction proceeds via the following steps: <br>1) Addition of trifluoroacetic acid to benzene<br>2) Addition of aminophenyl group to benzene<br>3) Addition of an alkyl group to benzene<br>4) Reaction of the newly formed 2-chloro-benzoyl chloride with ammonia<br>5) Reaction of the newly formed 2-aminobenzamide with hydrogen sulfide</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-fluoro-1H-pyrazolo[3,4-b]pyridine is a medicament for the treatment of cardiovascular diseases and cardiovascular disorders. It is in the form of a powder that is to be taken orally. 5-fluoro-1H-pyrazolo[3,4-b]pyridine has been shown to have an effect on inhibition of platelet aggregation and vasodilation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>