Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(3-Methylbutoxy)ethan-1-ol is an organic solvent that is used as a raw material in the production of activated carbon. It is also used as a base for the neutralization of acids, and can be converted to other compounds such as ethylene glycol. 2-(3-Methylbutoxy)ethan-1-ol has a viscosity of 1.5 cP at 20 °C and a density of 0.898 g/cm³, and can be used in the production of solar cells. This chemical can be synthesized from ethanol by catalytic hydrogenation or hydroformylation using molybdenum oxide or rhodium oxide on phosphoric acid.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Allyldihydro-2,5-furandione is a compound with a carbonyl group. It has been shown to be biocompatible and chemically stable in the presence of air and water. The chemical stability of the 3-allyldihydro-2,5-furandione is dependent on the linkage between its carbonyl group and the rest of its molecular structure. The ester linkages are more stable than ether or hydroxyl linkages. This compound has been shown to be an excellent candidate for use as a solvent in detergent compositions. 3-Allyldihydro-2,5-furandione can be synthesized by reacting phenol with 2,5-dihydroxybenzaldehyde and furan in an air entrainment reaction at an activation energy of 75 kJ/mol.</p>

<p>Tert-butyl N,N-dimethylcarbamate is a surfactant that is used as an amine. It is also an intercalator, which means it has the ability to bind to DNA. Tert-butyl N,N-dimethylcarbamate binds to DNA and disrupts replication by inhibiting the enzyme DNA polymerase. It can be used in validation of regulatory section and long-chain sequences.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,3,4,5,6-Hexahydroazepino[4,5-b]indole is a synthetic opioid that binds to the κ opioid receptor. It is an inorganic compound and has two asymmetric carbon atoms. The two enantiomers of 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indole have different affinities for the κ opioid receptor. The (R) enantiomer binds more tightly than the (S) enantiomer. This drug has been shown to stimulate dopamine d3 receptors and serotonin transporter activity. It also inhibits serotonin reuptake by binding to serotonin transporters in the presynaptic neuron. This action increases extracellular levels of serotonin that can activate postsynaptic receptors and produce antidepressant effects.</p>

<p>Benzene-1,3-disulfonyl fluoride is a reagent that can be used in organic synthesis. It can be used to synthesize carboxylic acids and amides from carboxylic acid chlorides and amines. This agent yields high yields of functional groups with little or no steric hindrance. Benzene-1,3-disulfonyl fluoride is also a strong nucleophile that can react with amine to form an intermediate which reacts with another molecule of benzene-1,3-disulfonyl fluoride to form the desired product. As a nucleophile, it is reactive toward biological molecules such as proteins and DNA.</p>

<p>2-(2,4-Dichlorophenyl)-2-hydroxyacetic acid (dichlophos) is a metabolite of the herbicide 2,4-dichlorophenoxyacetic acid. It is spontaneously generated in the cytosol and eliminated in the urine as its conjugate with glutathione. Dichlophos has been shown to inhibit the activity of glutathione transferase, which may be due to its ability to demethylate phospholipids and glutathione. Dichlophos has also been found to have an inhibitory effect on alkenyl and ketone metabolism, which may be due to its ability to block hydrogen phosphate synthesis. This compound has been shown to be metabolized by uronic acid oxidase in rats and humans, leading to the production of 2-keto-gluconic acid and hydrogen peroxide.</p>

<p>Versatile small molecule scaffold</p>

<p>Quinazolin-6-ol is a quinone that is synthesized by the reaction of anilines and phthalic acid. Quinazolin-6-ol inhibits NF-κB transcriptional activity in vitro, which may be due to its ability to bind to the heme moiety of the protein. This compound has been shown to have antibacterial activity against Gram-negative bacteria such as Phytophthora, but not Gram-positive bacteria such as Staphylococcus aureus or Bacillus cereus.</p>

<p>Quinazolin-7-ol is a cancer drug that inhibits the growth of tumor cells by blocking the activity of epidermal growth factor receptors. It has been shown to inhibit tumor growth in vivo and to have an antitumor activity. Quinazolin-7-ol also inhibits the activation of epidermal growth factor receptor and tyrosine kinase, which are factors that activate the cell cycle and promote tumor cell proliferation. As an antineoplastic drug, it has shown an inhibitory effect on lung cancer cells and other types of cancer cells in vitro. Quinazolin-7-ol can be used as a chemotherapeutic agent for drug resistant tumors.</p>

<p>2-(Chloromethyl)-5-hydroxy-4H-pyran-4-one (2CHP) is a nucleophilic compound that has been shown to be effective against colorectal adenocarcinoma cells. 2CHP is synthesized from the reaction of 2,5-dichloro-4H-pyran with hydroxylamine and HCl in water. It is also used for the treatment of infectious diseases such as malaria and tuberculosis. This compound induces tyrosinase activity through an intramolecular hydrogen bond with the hydroxyl group, which causes the hydroxyl group to become nucleophilic and react with a chlorine atom in order to form an acid conjugate.</p>

<p>Versatile small molecule scaffold</p>

<p>p-Toluenesulfonylmethyl Chloride is a reactive compound that can be used as an alkylating agent. It has a carbonyl group, which reacts with nucleophiles and can be used to form carbon-carbon bonds. p-Toluenesulfonylmethyl Chloride is also able to react with aldehydes and sulfoxides, forming anions and pyridazine. This chemical is used in the synthesis of organic compounds, including acetaldehyde. In addition, it can be used in magnetic resonance spectroscopy (MRS) experiments to identify the structure of aldehydes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Methylphenyl)propan-2-ol is an abiotic chemical that is used as a solvent for ethanol. It has been shown to be toxic to microalgae and fatty acids, by inhibiting the conversion of nitrate into nitrogen gas. 2-(2-Methylphenyl)propan-2-ol has also been shown to inhibit denitrification in the presence of nitrate and carbon sources. The mechanism of inhibition is unknown, but it may be due to the formation of an unidentified aromatic hydrocarbon that prevents nitrite reduction.</p>

<p>Versatile small molecule scaffold</p>

<p>Bromomethylphosphonic acid is a molecule that contains a carbonyl group, aliphatic hydrocarbon and an aromatic hydrocarbon. When reacted with humans, the molecule can be found in the reaction solution. Bromomethylphosphonic acid has been shown to have chemical stability and is not affected by alcohol residue or nitro groups. It has also been observed to inhibit fatty acid synthesis and to inhibit the activity of animal enzymes such as carboxylesterases in animals. This compound has optical properties that are acidic and are used in pharmaceutical preparations.</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dimethylpyridine-2-carbonitrile is a chiral organic compound that has the formula CHNO. It is used in organic syntheses as a building block for various products. 3,5-Dimethylpyridine-2-carbonitrile can be synthesized by nitroaldol reaction of 3,5-dimethoxybenzaldehyde and formaldehyde catalyzed by copper(II) acetate. This product is also an important intermediate in the synthesis of bipyridines and oxazolines, which are useful in the manufacture of catalysts and amino alcohols.</p>

<p>Versatile small molecule scaffold</p>

<p>(2S)-2-(Benzylamino)propanoic acid is an optical prodrug that has a high selectivity index against viruses. It is hydrolyzed to formamide and benzylamine in the presence of water, which can be used as a precursor for the synthesis of purines. 2-(Benzylamino)propanoic acid also has antiviral activity and can be used to synthesize nitroaromatic compounds. This compound displays nonlinear optical properties with an effective wavelength range of 400-500 nm, making it useful for applications such as laser treatment and photodynamic therapy. The solvents used in this reaction are n-dimethyl formamide (DMF) and hydrochloric acid.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2E)-2-(Propan-2-yl)but-2-enedioic acid is a solid catalyst for the oxidation of alcohols to carbonyl compounds. It is used in vitro to study the effects of genotoxic agents on cells and to evaluate the efficacy of cancer treatments. (2E)-2-(Propan-2-yl)but-2-enedioic acid has been shown to induce mutations in corynebacterium, corynebacterium glutamicum, and other bacteria. This compound can also be used as a neutral pH buffer in assays. The gene product catalyzes the conversion of oxaloacetate into acetyl coenzyme A (acetyl CoA). Acetyl CoA is an important intermediate in cellular respiration that helps to generate energy. In vivo tests have shown that (2E)-2-(Propan-2-yl)but-2-enedioic acid inhibits the growth</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl phenylsulfonylacetate (EPSA) is an organic compound that contains a hydroxy group, halides, and a hydrogen bond. EPSA inhibits the activity of palladium complexes by binding to the active methylene group. The phosphite group in EPSA may act as an absorber for electron density in the benzyl groups. This results in an intramolecular hydrogen bond formation and asymmetric synthesis that leads to higher isolated yields of EPSA.</p>

<p>The reaction rate of (R)-1-(pyridin-3-yl)ethanol is dependent on the type of organic ligands that are present. The biotransformations of this compound include triazolium, mutant, and biomolecular stereoselective reactions. The coordination of this compound with ionic liquids has been shown to be stereoselective. This molecule has also been synthesized using chiral ruthenium complexes as catalysts in order to generate a chiral product.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Amino-2-(1,3-dioxoisoindolin-2-yl)-5-oxopentanoic acid is a synthetic derivative that is used as a drug substance. It has been shown to inhibit the activity of glycosylases and eicosatetraynoic acid in human serum. The drug also inhibits the growth of cancer cells in CD-1 mice and humans. 5-Amino-2-(1,3-dioxoisoindolin-2-yl)-5-oxopentanoic acid has been shown to be reactive with hydroxyl ions, nucleophilic attacks, and nucleophilic groups. This drug can be used for the treatment of diseases such as HIV/AIDS and cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Bromomethyl)benzenesulfonyl fluoride (BMF) is a covalent inhibitor that binds to the active site of serum albumin and reversibly inhibits the enzyme. It has been shown to be an effective inhibitor, with low toxicity and high specificity for human serum albumin. BMF has been shown to inhibit the synthesis of glycosaminoglycans in human fibroblast cells. It also inhibits cellular protein synthesis and reduces the amount of albumin in serum.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Phenoxypropylamine is an alkylthio-substituted phenethylamine with a hydroxy group that is used in the synthesis of nitro, quinoline derivatives. It binds to the 5-hydroxytryptamine 1A receptor and inhibits serotonin reuptake. Phenoxypropylamine also has pharmacokinetic properties and is a transport inhibitor. This drug can be hydrolyzed by hydrochloric acid to form phenol and propranolol. In addition, it has been shown that phenoxypropylamine has a magnetic resonance spectroscopy binding site on human brain tissue. Furthermore, this drug has been shown to have an anti-inflammatory effect by inhibiting malic acid production in rats.</p>

<p>5-Amino-2-(4-aminophenyl)benzimidazole is a chemical compound that is used in the synthesis of other compounds. It can be prepared by the reaction of 4-aminophenol with 2,5-dichlorobenzene imidazole followed by hydrogenation and purification. 5-Amino-2-(4-aminophenyl)benzimidazole has a high resistance to both UV and thermal degradation. It has been shown to have low solubility in water, but high solubility in organic solvents such as chloroform, ethyl acetate, and cyclohexane. This compound shows an orthorhombic crystal structure and reacts with proton (H+) or chloride ion. 5-Amino-2-(4-aminophenyl)benzimidazole is also used as a reagent for gel permeation chromatography in order to</p>

<p>Versatile small molecule scaffold</p>

<p>1-Methoxy-1-phenylpropan-2-one is a carbonyl compound that has been shown to have anti-aging properties. It is used in the synthesis of other organic compounds, such as hyaluronic acid and benzyl benzoate, with the involvement of amination reaction or organometallic reactions. This chemical can be found in human urine as a metabolite of benzyl alcohol. The symptoms and signs of nervous system diseases may be due to the effects of 1-methoxy-1-phenylpropan-2-one on the human brain. The asymmetric synthesis of this compound is a new process that has been developed by chemists.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanamido]acetate is an antimalarial drug that has been shown to be effective against the parasite Plasmodium falciparum. It is a heptapeptide with a cyclic structure. This compound has been isolated from the fungus Penicillium griseofulvum and exhibits antimalarial activity in vitro. The chemical structure of Methyl 2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanamido]acetate was determined by spectrometry. Methyl 2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanamido]acetate can be synthesized by coupling of the</p>

<p>Versatile small molecule scaffold</p>

<p>1-Nitroso-2,3-dihydro-1H-indole is a heterocyclic compound that contains a nitrogen atom with a primary amino group. It can be used as an oxidant in organic chemistry and has been shown to yield good yields. This compound is also reactive towards other compounds containing carbon-hydrogen bonds and can be used as a nitrosoamine to form amides.</p>

<p>N-Acetyl-L-cysteine methyl ester (NACME) is a reactive compound that is the methyl ester of cysteine. It belongs to the group of amides and is an important component of human serum. NACME has been shown to be effective in inhibiting the growth of bacteria such as Staphylococcus aureus, Salmonella enterica, Escherichia coli, and Pseudomonas aeruginosa. The mechanism by which NACME inhibits bacterial growth is not yet known, but it may involve oxidative reactions or irreversible inhibition of enzymes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>OR-486 is a basic dye with pharmacological properties. It has been shown to have low-energy fluorescence, and it can be used for the detection of dopamine. OR-486 can also inhibit catechol-o-methyltransferase (COMT), an enzyme that catalyzes the methylation of catecholamines, including dopamine and epinephrine. In addition, OR-486 inhibits xanthine oxidase (XO) in vitro and in vivo. It has been shown to be effective against diabetic neuropathy in Sprague-Dawley rats as well as deficient mice. OR-486 has also been shown to increase the uptake of glucose by cells in a plate test.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Bromophenyl)azetidin-2-one is a β-lactam antibiotic that is used in the treatment of bacterial infections. It has a torsion angle of 180°, which is the same as other β-lactams, and it crystallizes in the monoclinic system with crystals that are planar. The molecular structure of 1-(4-bromophenyl)azetidin-2-one was determined using X-ray diffraction techniques.</p>

<p>7-Ethylquinoline is a quinoline derivative that has been shown to have potential as an antimalarial drug. 7-Ethylquinoline has been found to be effective against malaria parasites in the laboratory, with many of its derivatives having high yields and low toxicity. The structure of 7-ethylquinoline can be analysed by nuclear magnetic resonance (NMR) spectroscopy, which can also be used to identify the isomers present. 7-Ethylquinoline is a heterocyclic ring that contains a basicity at position 3, with a pKa value of 10.2. This chemical does not contain any contaminants and can be produced using various techniques.</p>

<p>5-Methylquinoline is a quinoline derivative that is used in the synthesis of other quinoline derivatives. It can be synthesized from cinnamaldehyde, which can be obtained from cinnamic acid or benzaldehyde. 5-Methylquinoline has been shown to have antioxidant properties and inhibit colorectal carcinoma cells in vitro. The compound also inhibits the growth of caco-2 cells. One isomer of 5-methylquinoline, ethenyl, has been shown to cause a shift in the spectrum of light absorbed by caco-2 cells.</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Trimethylsilyl)phenyl]methanamine is a pharmacological molecule that has been synthesized to have fluorine atoms. 4-(Trimethylsilyl)phenyl]methanamine is used in bioconjugate chemistry, which is the process of attaching two molecules together. In this case, the molecule attaches itself to a nucleotide. The fluorine atom helps stabilize the bond between the nucleotide and the molecule by increasing its electron affinity. This radiolabeled molecule can be used as a radioactive isotope in radiotracer studies to study how cells metabolize drugs and other agents.</p>

<p>The chemical formula for 2-amino-3-(methylsulfonamido)propanoic acid is C6H12N2O4S. It has a molecular weight of 218.25, and the molecular formula is CH3N(SO2CH3)COOH. This product is a white crystalline powder that can be dissolved in water or ethanol.</p>

<p>1-Propyl-1H-1,3-benzodiazole is a nitro derivative of the benzimidazole compounds. It is used in the preparation of azo dyes and as a dye intermediate. 1-Propyl-1H-1,3-benzodiazole is metabolized through oxidative or reductive pathways to form reactive intermediates that bind to DNA and protein substrates. This compound also inhibits fatty acid synthesis by forming ternary complexes with enzyme acyl carrier protein (ACP) and coenzyme A (CoA). The metabolism of 1-propyl-1H-1,3-benzodiazole leads to the formation of reactive metabolites that can cause congestive heart failure in mammals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methyl-1,5-naphthyridine is an antitumor agent that inhibits the activity of an efflux pump in tumor cells. The drug was shown to inhibit the proliferation of a tumor cell line in vitro and inhibited tumor growth in vivo. 4-Methyl-1,5-naphthyridine also has potent synergistic effects with carbon disulfide, which is used as a chemotherapeutic agent for cancer treatment. This compound also inhibits the production of endocannabinoids and has been shown to have antidepressant and antinociceptive properties in animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Vinylcyclopropane-1,1-dicarboxylic acid diethyl ester (VCPD) is a molecule that is synthesized by the nucleophilic attack of an alcohol on the double bond of a cyclopropane ring. VCPD is used in the production of polymers and copolymers. VCPD can be copolymerized with other monomers such as styrene, chloromethylstyrene, acrylonitrile, vinyl acetate, vinyl chloride and butadiene to produce various types of polymers. The polymerization process involves three steps: initiation, propagation and termination. Initiation takes place when persulfate is added to VCPD and water at high temperature. The polymerization process ends when there are no more VCPD molecules available for reaction or when all the monomers have been consumed during the reaction.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-bromo-3-hydroxypropanoate is a linear molecule that can be used to produce polymers and copolymers. This compound is polymerized with other monomers to form poly(methyl 2-bromo-3-hydroxypropanoate) (PMBH). It can also be used as a crosslinker in the production of polyurethane. Methyl 2-bromo-3-hydroxypropanoate can be made by reacting sodium carbonate, chloride, and trifluoride with methyl 3-methoxypropanoate. The reaction produces an intermediate that is then reacted with bromine gas to yield methyl 2-bromo-3-hydroxypropanoate.<br>Methyl 2-bromo-3-hydroxypropanoate is biodegradable and has been shown to have low toxicity. It has been used in a number of biomedical applications such as</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chlorophenyl Chloroformate is a chlorinating agent that has been shown to increase intracellular levels of carbon sources. It also has been shown to selectively act on the phenyl group of histidine and amines. 4-Chlorophenyl Chloroformate can be used as a synthetic intermediate in the synthesis of other compounds, including antidiabetic agents.</p>

<p>2-Naphthyl chloroformate is a chemical reagent that is used to derivatize amines for chromatography. The compound reacts with the amine and forms an ester, which can be used as a chromatographic stationary phase. It has been shown that 2-naphthyl chloroformate can be used to detect serotonin in urine samples by fluorescence detection. This compound is also used in the production of ethylene diamine and citric acid. 2-Naphthyl chloroformate is not toxic and does not appear to cause any adverse effects on human health at levels up to 1,000 ppm.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,4-Dimethoxy-²-methylcinnamic Acid is a phthalic acid derivative that is synthesized by the reaction of cinnamic acid with dimethylsulfate. It can be found in nature as well as being produced anthropogenically. This compound is used in the synthesis of medications and medicines. The chemical properties of 2,4-dimethoxy-²-methylcinnamic Acid are similar to those of related quinones and phenols, which makes it an effective agent for the treatment of hepatitis B and C. The chloride ion binds to the hydroxyl group on 2,4-dimethoxy-²-methylcinnamic Acid, forming hydrochloric acid (HCl) and water.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Amino-2-chloro-1,3,5-triazine is a potent soil microorganism that utilizes reactive amines and naphthalene as its sole carbon source. It is a polymorphic species that can form four different types of crystals, which are typically found in untreated soil samples. 4-Amino-2-chloro-1,3,5-triazine can be used for the biotransformation of chaperones and detoxification of xenobiotics. It is also capable of deaminating hydrophobic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,5-Dichlorobenzene-1-sulfonamide is a sulfonamide herbicide that inhibits the growth of plants by inhibiting the photosynthetic electron transport chain. It has been shown to have a high thermal stability and crystallizes from water solutions. 2,5-Dichlorobenzene-1-sulfonamide has been used for weed control and as an antioxidant for rubber products and paints. This compound has been shown to inhibit the production of reactive oxygen species in cells and thus reduce oxidative stress.<br>2,5-Dichlorobenzene-1-sulfonamide has also been found to be cytotoxic to human cells in culture at higher concentrations (10 μM).</p>

<p>3-tert-Butyl-1H-pyrrole is an organic compound that belongs to the group of primary amines. It can be synthesized by reacting 3-bromopyrrole with tert-butanol in the presence of a base catalyst. The cyclic voltammetry shows that this compound has a high oxidation potential, which makes it suitable for use as an electrochemical oxidation agent. The transfer rate constants are high, making this compound suitable for use in dehydrogenation reactions. 3-tert-Butyl-1H-pyrrole has been shown to have a high yield when reacted with amines in the presence of acetic acid and water.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,5-Dimethoxy-2-methylbenzaldehyde is a reagent that can be used to synthesize esters, isopropyl groups, and guanidine hydrochloride. It is also used in the synthesis of codeine, an opioid drug. This product has been shown to be an effective virulent agent against large-scale bacterial cultures of Escherichia coli and Pseudomonas aeruginosa. 4,5-Dimethoxy-2-methylbenzaldehyde is also a component of oxazolinones, which are a class of antibiotics.</p>

<p>Versatile small molecule scaffold</p>

<p>Monoethylglycinexylidine (MEGX) is a drug that has been shown to be effective in the treatment of chronic viral hepatitis. It has an activity index of 0.6-2.0 and can be used as a diagnostic tool for hepatic impairment. MEGX has also been found to be more effective in patients with primary sclerosing cholangitis than in those with non-primary sclerosing cholangitis. MEGX inhibits the P450 enzyme, which is involved in the metabolism of xenobiotics and endogenous compounds, and also inhibits Lidocaine-induced bronchoconstriction. The structural analysis of MEGX showed that it forms a stable complex with the active site of P450 enzymes, but does not form stable complexes with other enzymes such as cytochrome P450 reductase or epoxide hydrolase. In vivo experiments have shown that MEGX inhibits liver regeneration in mice by inhibiting hepatocyte</p>