Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methyl-6-oxo-1-phenyl-1,4,5,6-tetrahydro-1,2,4-triazine-3-carboxylic acid is a research tool that is an activator of ion channels. It can be used to study the gating mechanism of potassium channels and calcium channels. This compound has been shown to inhibit the activity of protein kinase C in cells and tissues. 5-Methyl-6-oxo-1-phenyl-1,4,5,6-tetrahydro-1,2,4--triazine 3 carboxylic acid has been used to identify new ligands for receptors such as the GABA receptor and serotonin receptor. This compound can also be used as a pharmacological agent for peptides and drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(3-Methoxyphenyl)propionaldehyde is a ligand that interacts with the mosquito Aedes aegypti. It has been shown to be orally active and has an affinity for the interaction site on the mosquito's olfactory receptor, which is responsible for detecting odors. 3-(3-Methoxyphenyl)propionaldehyde modulates this receptor, thereby interfering with the mosquito's ability to detect certain odors. It is also known to have an affinity for trypsin and collagen and can be used as a potential drug in treating breast cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-2-methylpropan-1-ol is a chiral, neurotoxic alcohol. It has been shown to be a precursor for the synthesis of neurotrophic analogues, which are compounds that help maintain the structure and function of neurons, such as 3-bromo-2-methylpropanal (BMPA) and 3-bromoacetophenone. The enantiomers of BMPA have different effects on fetal rat cerebral neuronal cells. One enantiomer inhibits the growth of neurons, while the other promotes their growth. These differences may be related to their optical activity: one enantiomer is active when present in the form of left circularly polarized light and the other is active in right circularly polarized light.</p>

<p>2-(2-Iodoethyl)-2,3-dihydro-1H-isoindole-1,3-dione is a crystalline compound that is an n-substituted derivative of phthalimide. It has been shown to be effective for the treatment of tuberculosis. This drug binds to DNA and inhibits transcription and replication. 2-(2-Iodoethyl)-2,3-dihydro-1H-isoindole-1,3-dione also inhibits bacterial growth by binding to RNA polymerase.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Phenyl-1H-pyrrole-3-carbonitrile is an acrylonitrile derivative that is a fungicide. It is used to control fungal diseases on plants and to prevent the spread of fungi in commercial buildings. The compound is used as a seed treatment and as a foliar spray. 4-Phenyl-1H-pyrrole-3-carbonitrile has been shown to be effective against many types of fungi, including species of Aspergillus, Alternaria, Cladosporium, Fusarium, Penicillium, Rhizopus, Scopulariopsis and Trichoderma. However it has little or no activity against bacteria or viruses. This fungicide can be absorbed through the skin and may cause kidney damage if ingested in large quantities.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dichlorophenethyl bromide is a heterocyclic compound that is an agonist of the farnesoid X receptor (FXR). It has been shown to be effective in treating metabolic diseases such as diabetes and obesity. 2,6-Dichlorophenethyl bromide has also been shown to reduce liver damage in experimental models of nonalcoholic steatohepatitis. This drug binds to FXR and activates the receptor, which then induces the production of bile acids. These bile acids are important for the digestion of fats and absorption of fat soluble vitamins. 2,6-Dichlorophenethyl bromide is metabolized by CYP3A4 enzyme and can cause drug interactions with other drugs that are metabolized by this enzyme.</p>

<p>2-Ethynylquinoline is a molecule that has been found to be effective in the treatment of leukemia and other cancers. It inhibits protein synthesis in cells by binding to the molecule eIF4E, which prevents the production of proteins vital for cell division. 2-Ethynylquinoline has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.<br>2-Ethynylquinoline is a potent cytotoxic agent that inhibits the growth of cancer cells by inhibiting protein synthesis and mitochondrial membrane potential. The drug also suppresses oxidative injury and cardiac dysfunction induced by fatty acid oxidation. In vivo studies have shown that 2-ethynylquinoline can cause regression of bronchial tumors in mice with pulmonary carcinomas, as well as regression of alveolar tumors in mice with metastatic lung</p>

<p>2-Ethynylbenzothiazole is a synthetic chemical that can be used as a fluorescent probe. It has been shown to react with nucleophilic compounds, such as thiols and amines, in the presence of palladium complexes. The reaction is catalyzed by the addition of hydrogen chloride. 2-Ethynylbenzothiazole reacts with thiols and amines to form a new compound called 2-chlorobenzothiazole. This reaction also produces hydrogen gas and heat. When 2-ethynylbenzothiazole is combined with vitamin B1, it undergoes electrophilic attack by an electron-rich heterocycle, leading to the formation of an intermediate product that fluoresces brightly.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenylbenzene-1-sulfonamide is a biphenyl compound that inhibits the production of endothelin, a peptide hormone that plays a role in regulating blood pressure and blood flow. It has been shown to be effective in vitro against experimental models of congestive heart disease and bowel disease. 2-Phenylbenzene-1-sulfonamide also inhibits the activity of x-ray crystal structures, which are proteins involved in apoptosis or programmed cell death. 2-Phenylbenzene-1-sulfonamide is not active against bacteria, but it has been shown to inhibit Mcl-1 protein, which regulates the process of apoptosis. This drug also has sodium salt forms that are used to treat metabolic disorders such as diabetes mellitus type II.</p>

<p>Versatile small molecule scaffold</p>

<p>N-(3-Acetyl-4-hydroxyphenyl)butanamide (NAAB) is a flavonoid that has been shown to be activated by the addition of urine samples. This activation leads to protein synthesis and exfoliation. NAAB fluoresces in the presence of an ultraviolet light, making it a useful fluorescent probe for the detection of human serum amide. NAAB is also low molecular weight and linear range, making it suitable for use as a reticulum deformation agent.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Iodo-2,5-dimethylthiophene is an alkenylation agent. It can be synthesized by reacting 3-iodo-2,4,6-trimethylphenol with boronic acid in the presence of ethylene at high temperatures. The reaction is irreversible and can be used to form substituted derivatives that are irreversibly alkenylated. 3-Iodo-2,5-dimethylthiophene has a number of optical properties including photochromism and diffraction. It has been shown to be useful for the synthesis of novel materials with optical properties such as photochromism and diffraction.</p>

<p>Methyl 2-cyclopentylideneacetate is a molecule that is used in cosmetics. It has viscosity-increasing properties, which are beneficial in products that require a creamy consistency. Methyl 2-cyclopentylideneacetate also has an average particle diameter of less than 20 microns and is soluble in water. This compound can be found in fatty acids, ethyl groups, and crystalline cellulose. The deodorizing effects of this product come from the particles it produces when mixed with magnesium oxide. Methyl 2-cyclopentylideneacetate also contains acidic ph levels and is an ester compound.</p>

<p>Methyl 2-cyclohexylideneacetate is a stereospecific, geranyl, and biomimetic chemical compound. It has been shown to be an effective inhibitor of bacterial enzymes that produce ozonides. Methyl 2-cyclohexylideneacetate also inhibits the biosynthesis of phytosteroids in plants and the synthesis of farnesyl diphosphate, which is an intermediate in the production of cholesterol. The compound has been postulated to inhibit bacterial enzyme activity by binding to the active site on the enzyme.</p>

<p>Mono-benzyl malonate is a synthetic molecule that inhibits the growth of cancer cells. It has an intramolecular hydrogen bond that stabilizes the molecule, and it has been shown to be effective at a low dose in preventing tumor growth. Mono-benzyl malonate also binds to receptors and blocks their activity, which may help to reduce insulin resistance in a similar way as metformin. The biological properties of this compound are still being studied.</p>

<p>4-(2-Methoxyphenyl)-3-thiosemicarbazide is a fluorescent compound that has been shown to have an inhibitory effect on bacteria. This compound binds to anions and can be used in the clarification of water. 4-(2-Methoxyphenyl)-3-thiosemicarbazide is also active as an antibacterial agent against gram-negative bacteria, such as Escherichia coli and Klebsiella pneumoniae. The antibacterial activity of 4-(2-Methoxyphenyl)-3-thiosemicarbazide may be due to its ability to inhibit the synthesis of proteins necessary for cell division.<br>4-(2-Methoxyphenyl)-3-thiosemicarbazide is a tautomeric, fluorescent compound that belongs to the class of antibiotic drugs. It has been shown to have chemosensor properties and can be used in the detection</p>

<p>4-(4-Methoxyphenyl)-3-thiosemicarbazide is a carbonyl compound that has been shown to have anticancer activity. It inhibits the growth of cancer cells by binding to the DNA of tumor cells, causing them to undergo apoptosis. 4-(4-Methoxyphenyl)-3-thiosemicarbazide also inhibits influenza virus and bacteria by inhibiting the enzyme ribonucleotide reductase and preventing the synthesis of viral RNA. This agent has potent inhibitory activity against gram-negative species such as Escherichia coli and Pseudomonas aeruginosa.</p>

<p>Versatile small molecule scaffold</p>

<p>6-(hydroxymethyl)pyridin-3-ol is a metabolite of the indole alkaloid, bufotenine. It has been shown to have cytotoxic activity against the human lung carcinoma cell line A549 and adipose cells, as well as antioxidant properties. 6-(hydroxymethyl)pyridin-3-ol also has been shown to modulate the production of reactive oxygen species in cells by inhibiting lipid peroxidation. This compound can be found in neutral pH environments, such as water and soil. 6-(hydroxymethyl)pyridin-3-ol can be synthesized from furfural or 5-hydroxymethylfurfural (HMF), which are produced through the degradation of glucose and other carbohydrates. The reaction between HMF with urea produces 6-(hydroxymethyl)pyridin-3-ol, leading to its presence in food chemistry.</p>

<p>Versatile small molecule scaffold</p>

<p>3-[(3-Aminopropyl)amino]-1-propanol is a complex chemical compound. It is a convergent synthesis and has the potential to be used in the field of chemistry, where it can be used to create new molecules with complex structures. 3-[(3-Aminopropyl)amino]-1-propanol can also be used to synthesize dendrons and dendrimers, which are highly symmetrical and designed architectures that have been shown to have orthogonal reactivity.</p>

<p>Thiazole is a heterocyclic organic compound that is composed of three carbon atoms and two sulfur atoms. They are classified as either acidic or basic, depending on the substituents. 4-(Hydroxymethyl)-1,3-thiazol-2-yl]methanol is a diluent that is used in pharmaceuticals and other chemical products. It has been shown to have cardiovascular, nervous and circulatory effects, as well as an effect on the central nervous system. This diluent also acts as a cholinesterase inhibitor, which causes acetylcholine to accumulate at nerve endings and results in paralysis of the victim’s voluntary muscles. This can lead to death if the victim cannot be treated with an antidote.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-2-oxopropyl acetate is a chloride compound that is used as an acid catalyst. It has been shown to exhibit hypochlorous and cytostatic effects in animals. 3-Chloro-2-oxopropyl acetate is also a structural modification of chloroacetone, which has been shown to have antitumor effects. This compound can be used as an acid catalyst for the synthesis of chlorinated benzoates. 3-Chloro-2-oxopropyl acetate also exhibits cytostatic and antiinflammatory activities in animal studies.</p>

<p>Benzyl 3,5-dimethylpyrrole-2-carboxylate is an enol ether that is stabilized by hydrogen bonds. This compound has a polymeric structure and forms dimers and dimers. The chains of the molecule are stabilized by hydrogen bonds. It has a carbonyl group and a carbonyl group that form hydrogen bonds with each other. There are also hydrogen bonding interactions between the benzyl chain and the acetyl groups present in the molecule. Benzyl 3,5-dimethylpyrrole-2-carboxylate is a part of the class of compounds known as polymeric ketones or polyketones, which are characterized by their chains of repeating units.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Ethenyl-2,3-dimethylbenzene is a monomer that is used to prepare polymers. It has coagulation properties and can be used as a solid catalyst for the production of polyurethanes. 1-Ethenyl-2,3-dimethylbenzene is an oxidizing agent that can react with styrene to form copolymers. This chemical has been immobilized on silica gel using a surfactant coating to produce coatings. The hydroxyl group in this compound is acidic and reacts with inorganic acids such as hydrochloric acid or sulfuric acid to form esters.</p>

<p>1-Ethenyl-3,5-dimethoxybenzene is a monomer that can be used for anionic polymerization. This monomer is characterized by its high yield, which is consistent with the predictable conformation of the phenyl ring and the symmetric nature of the magnetic resonance spectra. The 1-ethenyl-3,5-dimethoxybenzene molecule has an anionic charge. It is also known to have a phenolic group, which provides ultraviolet absorption properties. The temperature range for this monomer's transition ranges from -20°C to 100°C.</p>

<p>3-Hydroxybenzenethiol is a reactive chemical that binds to human liver microsomes and inhibits the activity of cytochrome P450, an enzyme that is required for the metabolism of many drugs. 3-Hydroxybenzenethiol has been shown to have inhibitory properties against a number of bacterial enzymes including beta-lactamase and penicillinase. 3-Hydroxybenzenethiol also inhibits the uptake of flavonoids by cells, which may be due to its ability to bind to flavonoid derivatives. The molecule has been used in studies on monoclonal antibodies and enzyme inhibitors.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Phenyl-1H-pyrazole-3-carbaldehyde is a pyrazole derivative that is used as a precursor in the synthesis of other compounds. The compound can be synthesized by nitro group reduction of 1,2,3-triazoles followed by chlorination of the resulting hydrazine. This reaction yields phenylhydrazones which undergo dehydrative condensation with carboxylic acids to give pyrazoles. These reactions are reversible and are catalyzed by acid or base. 1-Phenyl-1H-pyrazole-3-carbaldehyde has been shown to react with glucosyl residues in carbohydrates to form acetylated dihydroxyethyl moieties, which have been implicated in the prevention of diabetes and obesity.</p>

<p>Versatile small molecule scaffold</p>

<p>2-N,6-N-Dimethylpyridine-2,6-diamine is a macrocyclic diamine that has been synthesized in the form of a monoanion. It has an X-ray crystallography with a molecular structure that is consistent with the coordination of copper ions to two nitrogen atoms and two oxygen atoms. The ligand is coordinated in the axial position, with sulfate ions occupying the equatorial positions. The conformation of this compound is linear, which may be due to its negative charge. The crystal structure of 2-N,6-N-Dimethylpyridine-2,6-diamine is hexagonal.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Benzylphenylboronic acid is a heterocycle. It is an ester that can be made from the reaction of 2-benzylphenol and borane in the presence of ethanolamine. This compound has a 6-membered ring with three carbon atoms, two of which are attached to the boron atom. Pyrolysis results in the formation of benzene, nitrobenzene, and phenol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>9-(2-Aminoethyl)-9H-purin-6-amine is a nucleotide analog that has been used as a template for the synthesis of polymers with other heterocycles. The monomeric units are linked by crosslinks, which are formed by reacting two or more chains with an amine group on one of the chains. 9-(2-Aminoethyl)-9H-purin-6-amine is insoluble in water and reacts with cyanogen to form cyanuric acid. The phosphate groups can be reacted with chloride ions to form uracil, which is insoluble in water.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>