Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-tert-Butylphenylboronic acid (3TBBA) is an antibacterial agent that is used to treat bacterial infections. 3TBBA has been shown to be effective against methicillin-resistant Staphylococcus aureus and other bacteria. The mechanism of action of this drug is not well understood, but it may involve the inhibition of DNA synthesis. 3TBBA binds with high affinity to the enzyme RNA polymerase in the bacterial ribosome and inhibits its activity, leading to cell death by inhibiting protein synthesis. 3TBBA also has optical properties that can be seen using absorption spectroscopy and ultrafast spectroscopy methods.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Pyridin-3-ylmethyl)piperidin-4-amine trihydrochloride (1MP) is a basic, alkylating, multiphase, transfer catalyst. It is a phase transfer catalyst that has been used for the synthesis of organic compounds. 1MP has also been employed as a phase transfer agent in the synthesis of organic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-9,10-dihydrophenanthrene-9,10-dione is a quinone that has a density of 1.0 g/mL. This compound is insoluble in water and soluble in acetonitrile and tetrahydrofuran. It has been shown to be polymerized spontaneously at room temperature with no additives. 2-Amino-9,10-dihydrophenanthrene-9,10-dione is a molecule with an energy efficiency of 100% when synthesized by the tethering strategy. The synthesis of this molecule can be scaled up to industrial levels using the acetonitrile solvent as an additive.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Nitrothiophene-2-carboxamide is a synthetic compound that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. It has been shown to be a potent inhibitor of mycobacterial growth in vitro, with a minimum inhibitory concentration (MIC) of 0.5 µg/mL. The compound has also been shown to have antimycobacterial activity against cancer cells in culture by inhibiting DNA synthesis and inducing necrotic cell death. 4-Nitrothiophene-2-carboxamide has also been shown to be an effective inhibitor of cellular inflammatory responses and is currently being investigated as a potential therapeutic agent for treatment of cardiovascular disease.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-methyl-4-oxo-4-phenylbutanoate (MMOB) is an inhibitor of histone lysine methylation and demethylation. MMOB binds to the active site of protein and acts as a competitive inhibitor of histone methyltransferases. Methyl 2-methyl-4-oxo-4-phenylbutanoate can be used to study the effect of epigenetic changes on gene expression at the cellular level. This drug has been shown to have clastogenic effects in mammalian cells, which may be due to its ability to inhibit DNA replication by binding to actin filaments or its ability to alter the structure of chromatin.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(1-Phenyl-ethyl)-acetamide is a growth factor that can be used to treat cancer. It has been shown to have anti-leukemic activity, and the uptake of this drug by hematopoietic cells is thought to be due to its ability to bind to epidermal growth factor. N-(1-Phenyl-ethyl)-acetamide has also been shown in clinical studies to inhibit tumor perfusion, which may help prevent the spread of cancerous cells. This drug has been shown to also have antineoplastic effects against renal cell cancer.</p>

<p>6-Chloropyrazine-2-carboxamide is a tuberculostatic agent that inhibits the growth of Mycobacterium tuberculosis by alkylating nucleophilic sites on the bacterial cell wall. The antimycobacterial activity of 6-chloropyrazine-2-carboxamide has been shown in vitro using a densitometric assay, where it was able to inhibit the growth of M. tuberculosis. This drug also possesses antibacterial properties and has been shown to be effective against other bacteria such as Escherichia coli and Staphylococcus aureus. 6-Chloropyrazine-2-carboxamide is an amidating agent that reacts with amines to form amides or with carboxylic acids to form esters, which may have been used for its synthesis.<br>6-Chloropyrazine-2-carboxamide is a white crystalline powder that is soluble in water and alcohol</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydrazinoquinazoline is a type of inhibitor that binds to the polymerase domain of the ns5B enzyme and inhibits bacterial growth. The binding of 4-hydrazinoquinazoline to the polymerase domain of the ns5B enzyme prevents the formation of nucleotides, which are necessary for RNA synthesis. 4-Hydrazinoquinazoline has been shown to be an effective antibacterial agent with a broad spectrum against Gram-positive and Gram-negative bacteria, as well as fungi. It has also been shown to be active against Mycobacterium tuberculosis in culture. 4-Hydrazinoquinazoline is used in small amounts because it is unstable in aqueous solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>