Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(1-Methylethyl)-3-azetidinamine, hydrochloride (1:2) is a synthetic compound that has been shown to be a potent and selective γ-secretase modulator. It is a triol with an alcohol group at C-3 and two hydroxyl groups at C-4 and C-5. This compound has been shown to inhibit the production of cycloartenol from soybean oil in vitro, which may be due to its inhibition of γ-secretase activity. 1-(1-Methylethyl)-3-azetidinamine, hydrochloride (1:2) also has the potential for use as a target compound for research purposes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Imidazo[1,2-a]pyrazin-8-amine is a molecule that has been shown to be an inhibitor of protein kinase activity. It blocks the adenosine A3 receptor and is therefore a possible drug target for cancer. Imidazo[1,2-a]pyrazin-8-amine is an antimicrobial resistance determinant and has been shown to inhibit bacterial growth in vitro by binding to the adenosine A3 receptor. This molecule also inhibits the production of inflammatory cytokines such as TNFα and IL6 in human cells. Imidazo[1,2-a]pyrazin-8-amine may be useful for treating chronic inflammation, cancer, or both.</p>

<p>Pyrido[3,4-G]isoquinoline-5,10-dione is a nanosheet material with a layered structure. It has been shown to be able to absorb electromagnetic radiation and convert it into heat. The electronic spectra of this material changes when it interacts with light, which may be due to the transition between different molecular orbitals that are formed in the material. Pyrido[3,4-G]isoquinoline-5,10-dione has been shown to have anion and chiral properties. Boron nitride is often used as the substrate for this type of material because it has a high thermal conductivity and can be easily cleaved from the nanosheets.</p>

<p>[(2-Nitrophenyl)sulfinyl]acetic acid is a white powder that has a molecular weight of 214.2 and is soluble in water. It reacts with hydrogen to form nitrosyl, which is an electron acceptor. It also has the ability to stabilize hydrogen bonds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pyrazolopyridazine is a compound that has antiparasitic and antibiotic properties. It is used as an antiparasitic drug in the treatment of roundworm, hookworm, whipworm, and tapeworm infections. Pyrazolopyridazine is also used to treat bacterial infections such as tuberculosis. This drug has been shown to be effective against both Gram-positive and Gram-negative bacteria. Pyrazolopyridazine also exhibits antiviral properties against HIV-1 (human immunodeficiency virus) replication in human lymphocytes in vitro. The synthetic pathway of pyrazolopyridazine involves the condensation of 2-aminoacetophenone with 3-chloro-5-(2,4,6-trichlorophenyl)-pyridine followed by reaction with ammonia to give 3-amino-N-(2,4,6-trichlorophenyl)pyrazole.<br>Pyrazolopyr</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(Methoxycarbonyl)amino]-4-methylpentanoic acid (2-MePA) is a custom synthesis that is used as a building block in the synthesis of complex carbohydrates and polysaccharides. This chemical is modified with methylation, glycosylation, or fluorination to create saccharide derivatives. 2-MePA has been used in the synthesis of oligosaccharides and polysaccharides for use in biotechnology applications.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Chloromethyl)-3-methylpyridine hcl is a radiotracer that has been shown to bind reversibly to the synaptic vesicle protein synaptosomal-associated protein 25 (SNAP-25) in nonhuman primates. This drug has also been shown to be absorbed into the brain and to have pharmacokinetic properties. 4-(Chloromethyl)-3-methylpyridine hcl is a potential therapeutic agent for neuropsychiatric disorders, as it may reduce the binding of dopamine receptors in the brain. The affinity of 4-(chloromethyl)-3-methylpyridine hcl for SNAP-25 is dependent on the concentration of potassium ions, which suggests that this drug may also be used as an imaging agent for studying ion channels in humans.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Methylindole-5-boronic acid is a regioselective antimicrobial agent that inhibits microbial growth. This compound has been shown to inhibit the growth of both Gram-positive and Gram-negative bacteria, as well as fungi, in vitro. N-Methylindole-5-boronic acid has been shown to be effective against strains of Escherichia coli, Bacillus subtilis, and Pseudomonas aeruginosa. The antimicrobial activity of this compound was tested using an X-ray analysis and was found to bind strongly to the bacterial cell wall in a regioselective manner.</p>

<p>6-Hydroxy-1H-indole-3-carbaldehyde is an anion transporter that has been experimentally shown to inhibit the transport of anions across the plasma membrane. It was found to have significant inhibitory activity against hypouricemia and acetone. The localization of 6-hydroxy-1H-indole-3-carbaldehyde in fungi is unknown, but it has been shown to function as a transporter in macrofungi. 6-Hydroxy-1H-indole-3-carbaldehyde inhibits the uptake of anions by competing with them for the active site on the transporter protein. This mechanism may be due to its ability to bind with cations, which are also transported by these transporters. 6 hydroxy 1H indole 3 carbaldehyde is active against yeast cells and also shows some inhibitory activity against human erythrocytes when high concentrations are used.</p>

<p>3-(Ethanesulfonyl)pyridine is a synthetic chemical that has two reactive chlorine atoms and one reactive fluorine atom. It is used in the reduction of alkoxides to alcohols or amines, or in the preparation of chloroformates. 3-(Ethanesulfonyl)pyridine reacts with alkyl halides and carboxylates to form sulfonium salts, which are useful for preparing organic compounds. This compound has a pyridine ring with an ethanesulfonyl group attached to it. The n-oxide of 3-(ethanesulfonyl)pyridine also exists, which is less reactive than the c1-c3 n-oxide form.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Prinomastat is a small molecule that inhibits the protein MCL-1. It has been shown to inhibit tumor growth in mouse xenograft models of human breast, lung, and prostate cancer. This drug also blocks the expression of matrix metalloproteinases (MMPs), which are enzymes that break down collagen and other extracellular matrix components. Prinomastat inhibits iron homeostasis and induces apoptosis in epithelial cells, suggesting a role for this drug in the treatment of bowel diseases such as Crohn's disease.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Ethoxycyclohexan-1-ol is a volatile liquid. It is used as a solvent and chemical intermediate. It has been shown to be reactive with deuterium, trimethylsilanes, and other electron-deficient compounds. 4-Ethoxycyclohexan-1-ol also reacts with trimethylsilyl ether to form the corresponding trimethylsilyl ether derivatives. This reaction can be used for the labeling of silicon in organic syntheses. The reaction of 4-ethoxycyclohexan-1-ol with trimethylsilanes leads to rearrangement reactions that produce metastable products, which are unstable at room temperature.</p>