Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Bromobenzaldoxime is a biologically active molecule that has been shown to have significant physiological activities. It is an aldehyde, which is metabolized by the liver or kidneys into the corresponding alcohol, 2-bromoethanol. 2-Bromobenzaldoxime has been shown to be synthesized from diethyl ether and potassium phosphate in the presence of amino acids. The reaction proceeds with dehydration of the intermediate bromohydrin to form an aldoxime. This molecule can be used as a pharmaceutical drug for various diseases such as diabetes mellitus, hypertension, and inflammation.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chloro-3,4-dihydronaphthalen-1(2H)-one is a sulfoxide with significant antifungal activity. It has been shown to be effective against Candida albicans and other fungi, including Aspergillus niger and Mucor racemosus. It is commonly used as an electrolyte in electroluminescent devices, such as light emitting diodes (LEDs). The reaction time for the formation of 2-chloro-3,4-dihydronaphthalen-1(2H)-one from potassium sulfate is dependent on the acid catalyst used. Organic chemists have shown that the use of 2-chloro-3,4-dihydronaphthalen-1(2H)-one can inhibit leukotriene synthesis.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Bromo-2-butoxybenzene is a chemical compound that is used in the manufacture of zinc oxide. It is also used as an electrolyte in dye-sensitized solar cells. In these cells, 1-bromo-2-butoxybenzene acts as an electron donor, which provides electrons to the redox dye on the surface of the semiconductor. This process leads to recombination, where electrons and holes recombine to produce electricity. The introduction of alkoxy groups into 1-bromo-2-butoxybenzene molecules allows for increased stability and efficiency in dye-sensitized solar cells.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chloro-1-(4-ethoxyphenyl)ethan-1-one is a hydrocarbon radical that is used as a vitamin and in the synthesis of other molecules. This molecule has a covalent bond between the two chlorine atoms and one carbon atom. The hydrocarbon radical is also present in many hydrocarbons.

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.