Building Blocks

<p>Versatile small molecule scaffold</p>

<p>4-Iodo-m-xylene is an organic solvent that is used as a precursor in the synthesis of medicines. It is a member of the methyl group with hydrogen, chlorine and other elements. 4-Iodo-m-xylene has been shown to be activated by both hydrochloric acid and hydrogen peroxide, which leads to the formation of methylbenzenes. The chlorides are then added to form enolate anions, which can be protonated by hydrogen chloride to form ligands. These ligands can react with peroxide to produce biomolecules such as proteins or nucleic acids.</p>

<p>2-Chloro-1-(2-chlorophenyl)ethanone is an antiarrhythmic drug that belongs to the group of methyl ketones. It is used to treat asthma and bronchitis. 2-Chloro-1-(2-chlorophenyl)ethanone is a chiral compound with two possible enantiomers. The rotation of the molecule can be altered by changing the solvent. The dihedral angle between two hydrogen bonds in this molecule can also be changed, which affects the way that it interacts with bronchial receptors. This compound has been shown to have antiarrhythmic properties, as well as being able to inhibit transfer hydrogenation reactions in cyclohexane.</p>

<p>1-(Furan-2-yl)-2,2-dimethylpropan-1-one is a catalytic reagent that is used in the synthesis of furan derivatives. 1-(Furan-2-yl)-2,2-dimethylpropan-1-one can be produced from 2,5-dihydrofuran with carbon tetrachloride and PCl5 or by reacting 2,5-dihydrofuran with CCl4. This product reacts as a dipole and has been shown to have some experimental and theoretical uses in catalysis. It is also a reactant in the production of acetophenone and pyridine. The abundances of this product are determined by the constants A = 3.14159 × 10−8 m²/s², B = 4π × 10−7 m³/s¹, C = 1.6180 × 10−3 m/s and D</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-2,2-dimethylpentanenitrile is a nonpolar solvent that can be used as a phase transfer catalyst and reagent for the synthesis of cyclopentanone derivatives. It is also used as a hydrolyzing agent for the synthesis of 1-bromo-3-chloropropane. 5-Chloro-2,2-dimethylpentanenitrile can be used to synthesize cyclic ketones from alkyl halides and 1,1'-oxydiacetonitrile with an acetone or isobutyronitrile as a catalyst.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Prop-2-en-1-yl)oxane is a tetrahydrofuranyl compound that is used in organic synthesis as an allylation agent. It is also used in the functionalization of ethers, multicomponent reactions, derivatization reactions, and many other chemical syntheses. 2-(Prop-2-en-1-yl)oxane is typically used as an anhydride or ester catalyst. It has been shown to catalyze the reaction between ethyl acetate and propylene oxide.</p>

<p>4,6-Dichloroquinoline is a macrocyclic compound that has been found by accident. It inhibits the growth of malaria parasites by binding to the enzyme heme oxygenase. The inhibition of this enzyme leads to an accumulation of toxic products derived from the heme molecule and causes cell death. 4,6-Dichloroquinoline is also fluorescent and can be used as a reagent for cross-coupling reactions or as an antimalarial drug. The compound fluoresces when it binds to metal cations such as chloride and ligands such as chloride ions. This property can be used in the detection of these species in solution or in solid samples.</p>

2-Chloro-4-methylphenyl-N-(2-chloro-4-methylphenyl)-4,5-dihydroimidazol-2amine is a potent immunosuppressive drug. It has been shown to be effective in the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. The drug has been found to be safe and effective in animal models of cardiac disease. 2C4MPI is an analog of azathioprine, which is used for the treatment of inflammatory and autoimmune diseases. In addition, this drug has been shown to have antihyperglycemic properties by inhibiting glucose production in the liver and increasing insulin sensitivity in muscle tissue. 2C4MPI also reduces collagen synthesis, which may be useful in treating inflammatory diseases that are caused by excess collagen deposition such as skin conditions like psoriasis or acne vulgaris.

<p>Ethyl (E)-cinnamate is a cinnamic acid derivative that belongs to the class of phenylpropenoids. It has been shown to have biological properties, such as enzyme activities and antioxidative properties. Ethyl (E)-cinnamate has also been shown to be a potent photosynthetic activator in vitro. This compound can be used as a precursor for the synthesis of cinnamic acid, which is important in the metabolism of energy production and locomotor activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Pent-1-yn-3-ol is a low molecular weight compound that is classified as an amide. It is an intermediate in the biosynthesis of fatty acids and primary alcohols from acetyl-CoA. Pent-1-yn-3-ol also alkylates amides in proteins, and can be used for the synthesis of magnetic nanoparticles. In order to determine the effects of mononuclear alkali metal ions on organisms, methyl ethyl was added to a mixture of 10 mM potassium hydroxide (KOH) and water. The pH was then adjusted to 4 with hydrochloric acid (HCl). A magnetic stir bar was placed in the flask, and the solution was mixed magnetically at room temperature. The growth rate of Drosophila melanogaster was monitored over time by measuring its wet weight.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Phenyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-one is an optically active compound that is used in the synthesis of other drugs. It can be synthesized by reacting carbamoyl chloride with hydrogen and hydroxide. This compound has a nitro group at position 5 and a trifluoromethyl group at position 2. The asymmetry of this molecule is due to the c1-6 alkyl group on the left and the c1-4 alkyl group on the right.</p>

<p>Versatile small molecule scaffold</p>

<p>Decahydroquinolin-2-one is an estrogen receptor modulator that has a stereoselective binding to the ligand binding domain of the estrogen receptor. It binds to the hydroxyl group on the A ring and forms hydrogen bonds with residues in the ligand binding domain, which are important for the activation of estrogen receptors. Decahydroquinolin-2-one has been shown to have anti-depressant properties, which may be due to its ability to inhibit dopamine reuptake and increase dopamine levels in the brain. The chlorination of decahydroquinolin-2-one at position 2 may contribute to its stability against oxidation.</p>

<p>1-(1,2,3,4-Tetrahydroquinolin-1-yl)ethan-1-one is a hdac inhibitor that binds to the enzyme histone deacetylase (hdac). It has been used to study Alzheimer's disease and other neurodegenerative diseases. This drug is an amide with a carbonyl group. It is also a biphenyl molecule that can be prepared by reacting phosphorus pentoxide with biphenyl. 1-(1,2,3,4-Tetrahydroquinolin-1-yl)ethan-1-one has shown inhibitory effects on metal hydroxides such as calcium hydroxide and magnesium hydroxide. 1-(1,2,3,4-Tetrahydroquinolin-1-yl)ethan-1-one also inhibits the formation of hydrochloric acid from hydrogen chloride and sodium hydroxide. The aromatic hydro</p>

<p>2-(2-Methylpropyl)phenol is a hydroxylated aromatic compound. It is used as a solvent in the production of hydroxybenzoic acid, which is an intermediate in the synthesis of biofuels. 2-(2-Methylpropyl)phenol has been shown to be an effective water treatment agent at low concentrations. This chemical also has optical properties that can be exploited for liquid crystal compositions and in the development of new materials with improved optical properties. 2-(2-Methylpropyl)phenol contains two phenyl groups, which can undergo substitution reactions with chloride or hydrogen chloride. The resulting products are alicyclic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Propan-2-yl)pentanedioic acid is an oxidation product of α-pinene, β-caryophyllene, and isoprene. It has been used as a tracer in gas chromatography/mass spectrometry to identify the sources of carboxylic acids in tobacco smoke. The compound has also been used as an analytical standard for carboxylic acids and lactones. 3-(Propan-2-yl)pentanedioic acid is found in high concentrations in aerosols from e-cigarettes, which have been shown to contain other compounds that may be harmful to health.</p>

<p>2-Ethylhexanamide is a fatty acid amide that is metabolized by the liver. It has been shown to have antiepileptic activity in animal models, and can be used as a substitute for phenytoin. 2-Ethylhexanamide is also metabolized to form an amide with chloride ions, which may be responsible for its anti-epileptic effects. The pharmacokinetics of 2-ethylhexanamide are well understood in animals and humans, where it is eliminated unchanged in the urine. This drug also has functional groups that allow it to react with other compounds and undergo biotransformation reactions.</p>

<p>1-Phenyl-2-[(propan-2-yl)amino]ethan-1-ol is a homologous analog of puromycin. It is an ester that inhibits the RNA polymerase II enzyme, which is essential for DNA synthesis. The onset of 1-phenyl-2-[(propan-2-yl)amino]ethan-1-ol is relatively rapid. It has been shown to inhibit cellular RNA synthesis and DNA synthesis in the parotid gland, as well as RNA and protein synthesis in the salivary glands. This drug has also been used to study the effects of diphtheria toxin on bacteria.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Phenyloxane-2,6-dione is a molecule that has two asymmetric carbons. The molecule has been shown to undergo desymmetrization by the Friedel-Crafts acylation and protonation reactions. 4-Phenyloxane-2,6-dione has been used as a chiral catalyst to synthesize an α,β-unsaturated ketone with an unsymmetrical double bond. <br>4-Phenyloxane-2,6-dione can be used for asymmetric synthesis of aldehydes due to its bifunctional nature. This compound is also used in the catalysis of cyclic reactions.</p>

<p>2-(4-Methoxybenzoyl)thiophene is a functional group that is an acceptor. It is used in solar cells, where it interacts with the electron donating group to form a charge transfer complex. This complex aids in the conversion of light into electricity. The efficiency of these devices can be improved by using fullerenes, which are electron accepting and electron donating groups. 2-(4-Methoxybenzoyl)thiophene's interaction with other functional groups, such as phenylsulfonyl chloride, has been shown to produce electronic interactions in solar cells.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3-Methyl-3-azabicyclo[3.2.1]octan-8-one is a synthetically produced pyrrolidine that has been synthesized by reaction of piperidine with ethyl acetate and formaldehyde. The 3-methyl group of the molecule is attached to the nitrogen atom and this ring forms a conformation that is different from other rings in the pyrrolidine family. The conformational study was done by NMR spectroscopy and the experimental, spectroscopic study was done on conformational changes by substituents on the piperidine ring.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Benzoylpentanoic acid is a chemical compound that has been shown to be an effective bactericidal agent against Gram-positive and Gram-negative bacteria. It is synthesized by the hydrogenation reduction of 5-benzoylpentanal, which is obtained from the oxidation of benzaldehyde with nitric acid. The synthesis of 5-benzoylpentanoic acid can be carried out in two steps: first, a benzaldehyde ester is obtained by reacting benzaldehyde with methyl acrylate in the presence of a base; second, the ester reacts with sodium hydroxide to produce 5-benzoylpentanoic acid. This chemical is also an organic solvent that can be used in the organic synthesis of other compounds. This compound has been shown to have inhibitory activity against oxocarboxylic anions such as phosphoric acid and perchloric acid.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-4-chlorobenzene-1-sulfonamide is a sulfa drug that inhibits the growth of bacteria by inhibiting the synthesis of folic acid. It is used for the treatment of staphylococcus and other bacterial infections, although it does not show any effect on gram negative bacteria. 2-Amino-4-chlorobenzene-1-sulfonamide binds to enzymes in the bacterial cell wall, which prevents them from synthesizing folic acid. This results in inhibition of DNA synthesis and protein synthesis, leading to cell death. 2-Amino-4-chlorobenzene-1-sulfonamide also shows antibacterial activity against Salmonella typhi and Shigella dysenteriae because these organisms are sensitive to sulfa drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-methyl-3-sulfanylpropanoate is a fruity, tropical, and detergent scented ester with a fruity odor reminiscent of fruits. It is used in the manufacture of shampoo, as an acid methyl ester, or as an ethyl ester. This chemical has been used as a tobacco flavorant and can be found in the form of its methyl ester. Methyl 2-methyl-3-sulfanylpropanoate has been shown to have detergent properties when it is reacted with sodium hydroxide.</p>

<p>(S)-3-Amino-2-pyrrolidinone is a potent inhibitor of serine proteinases, including trypsin, chymotrypsin, and elastase. It also has anti-coagulant properties that are similar to heparin. (S)-3-Amino-2-pyrrolidinone is used in the treatment of carotid artery disease and as an anticoagulant in deep vein thrombosis prophylaxis. This drug can be used in the prevention or treatment of thrombus formation due to its ability to inhibit coagulation and fibrinolysis. It is also a potent inhibitor of thrombin, which is an enzyme involved in blood coagulation. The development of this drug was inspired by the discovery of the importance of serine protease inhibitors for blood clotting and other physiological processes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chlorophenoxyacetyl Chloride (4CPAC) is a synthetic compound that has been shown to have biological properties in the inhibition of cell function, which may be due to its ability to bind with a specific ligand. 4CPAC is also a pesticide and has been shown to be effective against nematodes and pests. 4CPAC has hypotensive effects and can be used as an antihypertensive drug. The hydroxyl group on the left side of the molecule enables it to act as a sulfoxide, which is an organic chemical that reacts with other molecules in order to form new compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline is a phenyl conformation molecule that has an x-ray structure. This compound is a β-blocker and can be used to treat heart conditions such as angina pectoris and arrhythmia. It also has antiarrhythmic properties. 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline has two substituents at the 6 and 7 positions on the isoquinoline ring. The chains are attached to the phenyl ring by hydrogen bonds.</p>

<p>4-Ethylpiperazine-1-sulfonamide is a potent compound that inhibits the production of lipopolysaccharide. This inhibition leads to less inflammation and pain in patients with rheumatoid arthritis and other inflammatory diseases. 4-Ethylpiperazine-1-sulfonamide has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in human macrophages by blocking the activation of nuclear transcription factor kappa B (NFκB). This compound also binds to the TNF receptor, inhibiting its ability to activate NFκB. 4-Ethylpiperazine-1-sulfonamide also has antiinflammatory activities and can be used for the treatment of chronic inflammatory disorders such as rheumatoid arthritis.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Chloro-4-methylpentan-2-one is a chemical compound that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to inhibit methicillin resistance in Staphylococcus aureus, and also has an antibacterial effect on other gram-negative bacteria. 1-Chloro-4-methylpentan-2-one is active against both gram positive and gram negative organisms, but the spectrum of activity is limited because it is not active against acid fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. 1CMTD has been shown to be stable in its crystalline form and can be administered orally.</p>

<p>3,5-Dinitrobenzonitrile is a chemical compound that is used as a reagent in organic synthesis. It is carcinogenic and has been shown to produce tumors when administered intraperitoneally. 3,5-Dinitrobenzonitrile has been found to react with hydrochloric acid in the presence of nitrous acid to form chloride, nitro, and water. The reaction mechanism of this process involves dehydration at the C-N bond followed by an amide formation. This reaction product can be observed using magnetic resonance spectroscopy (NMR).</p>

<p>4-(1H-1,3-Benzodiazol-2-yl)benzonitrile is a planar molecule with a dihedral angle of about 120°. The molecule consists of benzene rings and chains. The benzene ring is symmetrical, hence it has no plane of symmetry. As the molecule does not have any chiral centers, there are two enantiomers (mirror images).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Piperidine-1-sulphonamide is a hydrogen bond inhibitor that binds to bacterial enzymes, inhibiting the production of proton. It has been shown to have anti-inflammatory activity and is used in the treatment of inflammatory diseases such as autoimmune diseases, HIV infection, and cancer. This drug also has an effect on purine metabolism, which may be due to its ability to inhibit bacterial enzyme adenosine deaminase. Piperidine-1-sulphonamide also inhibits inflammation in bowel disease by suppressing the release of inflammatory cytokines such as tumor necrosis factor and interleukin 1beta.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Pyrrolidinesulfonamide is an anti-infective agent that inhibits the growth of bacteria by inhibiting their ability to synthesize proteins. It binds to cellular DNA and prevents transcription, leading to apoptotic cell death. 1-Pyrrolidinesulfonamide has been shown to have chemoattractant properties and can be used as a pharmacokinetic marker for differentiating bowel disease from cancer in vivo models. This drug also has been shown to inhibit inflammatory bowel disease in vitro and in vivo. 1-Pyrrolidinesulfonamide is a quinoline derivative that can hydrogen bond with nucleic acids and interfere with RNA synthesis. It also has been shown to inhibit the production of proinflammatory cytokine, such as IL-6 and TNF-α, which are involved in inflammatory diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Isocyanatocyclohex-1-ene is a colorless liquid that is soluble in water. It is used as a raw material for the production of polyurethane and other polymers, which are used in coatings, adhesives, elastomers, and other industrial applications. 4-Isocyanatocyclohex-1-ene can be found as part of a mixture or polymer with other diisocyanates. The chemical has been shown to form when certain cycloaliphatic compounds are heated to high temperatures.</p>

<p>Versatile small molecule scaffold</p>

<p>Cyclooctanecarboxylic acid is a hydroxylated monocarboxylic acid that has been shown to inhibit the activity of various enzymes. It is a polar molecule with a diameter of about 1.5 nm, which can be used as a polarizer in light microscopy. Cyclooctanecarboxylic acid has been shown to inhibit the production of hepatitis C virus particles and insulin resistance in mammalian cells. It also inhibits viral replication by interfering with the synthesis of viral proteins, inhibiting protein synthesis and cell division. Cyclooctanecarboxylic acid is an inhibitor for many compounds, including inhibitors for cholesterol biosynthesis, human immunodeficiency virus type 1 protease inhibitors, and protein kinase C inhibitors.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Propan-2-yl)thiophene is a cyclopropylamine that reacts with ruthenium to form a ruthenium complex. This complex is thermodynamically stable, and can absorb light in the visible region of the spectrum. The addition of ligands such as phenanthroline or isopropyl groups enhances its photophysical properties, and can be used to catalyze alkylation reactions. 2-(Propan-2-yl)thiophene has an electron-withdrawing group on the phenyl ring, which makes it susceptible to nucleophilic attack by electrophiles. This property is useful for kinetic studies of alkylation reactions, because it allows for observation of the rate at which an alkylating agent approaches a given substrate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>