Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The synthesis of (2-bromophenyl)(phenyl)methanol is accomplished by the reaction of an aldehyde with bromine followed by an alkylation with magnesium. The product is obtained as a racemic mixture of enantiomers with a chiral center, which can be resolved by fractional crystallization or other separation methods. This method has been shown to be efficient for the synthesis of alcohols and carbinols, and stereogenic reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Flindersia laevicarpa is a small tree native to Australia. The leaves of the tree are used for medicinal purposes and contain 1,5-diphenylpentan-3-ol. Flindersia laevicarpa has been shown to have anti-inflammatory and antioxidant properties, as well as an ability to inhibit platelet aggregation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Quinoline-5-carbonitrile is a cyanide compound that can be used in the synthesis of heterocyclic compounds. The reaction between quinoline and 5-cyanovaleric acid produces 6-nitroquinoline, which is then converted to dimethyl sulfoxide by alcoholysis. This reaction product can then be used to synthesize an amide or nucleophile. Quinoline-5-carbonitrile reacts with potassium in the presence of bifunctional hydrazide to produce a cyanide ion, which can be hydrolyzed by an acid to release hydrogen cyanide gas. This experiment has been shown as a model for reactions involving cyano compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-1,2,4-benzotriazine is an organic compound that is used as an anti-cancer agent. It is a cytotoxin that inhibits the growth of cells by binding to DNA. The Suzuki reaction was used to synthesize this compound in high yields. 3-Chloro-1,2,4-benzotriazine has potential anti-cancer activity and can be used in conjunction with other cytotoxic agents to treat cancer. This drug has been shown to have cytotoxic effects on tumor cells by inhibiting DNA synthesis and cell division.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Thienopyridine analogs are a class of chemical compounds that function as agonists of the receptor α. These compounds have been shown to inhibit fatty acid oxidation and ATP production in rat liver cells, which may be due to their ability to activate AMP-activated protein kinase (AMPK). Thienopyridine analogs are being investigated for use as anti-inflammatory agents and cancer treatments.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>

<p>Versatile small molecule scaffold</p>