Building Blocks

N-Ethylglycine hydrochloride is a pharmaceutical preparation that inhibits the enzyme cholesterol esterase. It is used to treat congestive heart failure and as a diuretic. N-Ethylglycine hydrochloride prevents the production of unsaturated fatty acids by inhibiting the enzyme cholesterol esterase, which converts cholesterol into fatty acid. This leads to lower levels of cholesterol in the blood, which can be beneficial in treating high cholesterol levels. N-Ethylglycine hydrochloride has been shown to have antiviral effects against influenza virus, with an IC50 of 0.5 μM, as well as anti-inflammatory properties.

Versatile small molecule scaffold

5-Bromo-furan-2-carbonyl chloride is a colorless liquid that is soluble in organic solvents. It has a thionyl, polymerized odor and can be used as a feedstock for the production of amines, cyclopentadienyl, and chloride. 5-Bromo-furan-2-carbonyl chloride also has radiation damage properties and can be used in radiochemical synthesis of pyrrole. This chemical has been used to produce glycosides by reacting with diluents such as methanol and ethanol.

Versatile small molecule scaffold

Versatile small molecule scaffold

5-Chloro-1-tetralone is an oxime that is used as a topical agent for the treatment of staphylococcal infections. It acts by inhibiting bacterial cell wall synthesis, preventing the formation of cross-links between the peptidoglycan chains. 5-Chloro-1-tetralone has potent antibacterial activity against many bacteria and fungi. This compound has shown to be effective against escherichia coli, pneumoniae, and imidazole derivatives. The mechanism of action is not well understood, but it may involve inhibition of protein synthesis or DNA replication by binding to enzymes involved in these processes.

(2R,3S,4R,5R)-Oxane-2,3,4,5-tetrol is a ligand that binds to metal ions and isomers of nitro groups. This compound has four chiral centers and two stereogenic centers. It has been used as an immobilized catalyst in the synthesis of enantiopure alcohols and aldehydes. (2R,3S,4R,5R)-Oxane-2,3,4,5-tetrol can be used as a feedstock for the production of polyols or polymers. It can also be used in fermentations such as the conversion of sugars into alcohols using yeast. (2R,3S,4R,5R)-Oxane-2,3,4,5-tetrol is transported across cell membranes by active transport or diffusion. Growth temperature affects its solubility in water and its ability to form hydrogen bonds

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

5-Iodopentanenitrile is a reactive chemical that can be used to produce organic compounds. This compound is an intermediate in the production of 5-iodo-1,3-dihydrobenzofuran and 5-iodoquinoline. It is also used for the production of pharmaceutical intermediates such as fluoroquinolones and alkylating agents. The mechanism of this chemical's reactivity has been studied extensively, which led to the discovery that it reacts by nucleophilic addition at electron deficient carbonyls groups. These reactions are known as Grignard reactions or halolactonizations. This chemical has also been shown to be reactive with biomolecules, such as DNA and RNA, and can bind to their sugar residues.

Versatile small molecule scaffold

Versatile small molecule scaffold

Sinensetin is an anti-inflammatory compound that belongs to the chromones class of compounds. Sinensetin has been shown to have anti-inflammatory properties at high temperatures in experimental models. The mechanism of action for sinensetin is not well understood, but it may be due to the inhibition of prostaglandin synthesis or by direct interaction with TNF-α. Sinensetin also has antioxidant and antifungal properties, which are attributed to its ability to scavenge free radicals and inhibit lipid peroxidation. Sinensetin was found in a variety of plants from China, including Acanthopanax senticosus and Eurycoma longifolia.

Versatile small molecule scaffold

Versatile small molecule scaffold