Building Blocks

<p>Applications O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.<br>References Sun, Y. et al.: Chin. J. CHem., 31, 1199 (2013); Akama, T. et al.: Bioorg. Med. Chem. Lett., 23, 5870 (2013);<br></p>

<p>Applications 2-Methoxy-4-aminobenzoic Acid (cas# 2486-80-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Methoxyacetaldehyde Dimethyl Acetal is a reagent used in balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-1R inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zimmermann, K., et al.: Bioorg. Med. Chem. Lett., 18, 4075 (2008);<br></p>

<p>Applications 5-Oxo-5-phenylvaleric Acid is used in various synthetic preparations. It is used in the synthesis of fulleroid and methanofullerene derivatives. Also used in tertiary amino urea-catalyzed enantioselective iodolactonization.<br>References Hummelen, J., et al.: J. Org. Chem., 60, 532 (1995); Veitch, G., Jacobsen, E.: Angew. Chem. Int. Ed., 49, 7332 (2010);<br></p>

<p>Applications (1-Ethoxycyclopropoxy)trimethylsilane used as a reactant in the synthesis of di-, tri- and tetracyclopropylhydrazines. Also used as reagent in the synthesis of g elsemoxonine which is found in gelsemium plant species that is used in traditional asian medicine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shestakov, A., et al.: Chem. Commun., 52, 2398 (2016); Diethelm, S., et al.: J. Am. Chem. Soc., 137, 6084 (2015);<br></p>

<p>Applications 3-Methylamino-1,2-propanediol (cas# 40137-22-2) is a useful research chemical.<br></p>

<p>Applications 1-Bromodecane is used to react with Mg to prepare Grignard reagents which play an important role in formation of carbon-carbon bond. It is also used in preparation of biodegradable cationic gemini surfactants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rogers, R., et al.: J. Org. Chem., 39, 857 (1975); Talaba, P., et al.: J. Carbohyd. Chem., 16, 573 (1997); Jain, T., et al., J. Mater. Chem. C: Materials for Optical and Electronic Devices, 2, 994 (2014)<br></p>

<p>Applications 3-Iodoanisole (cas# 766-85-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.<br>References Keul, H., et. al.: Macromol. S., 19, 1 (1971)<br></p>

<p>Stability Moisture Sensitive<br>Applications 10-Bromodecanol can be used to synthesize rotaxane dendrimers. It can also be used to synthesize J2326, a molecule that induces neurite outgrowth in neuronal cells.<br>References Wei, W., et al.: Proc. Natl. Acad. Sci. USA 112, 5597 (2015); Chang, P., et al.: Neuropharmacology 92, 146 (2015)<br></p>

<p>Applications 4,5-Dimethyl-3-isoxazolamine is an isoxazole derivative used in the preparation of a varitey of biologically active compounds such as selective ETA receptor antagonists.<br>References Murugesan, N. et al.: J. Med. Chem., 46, 125 (2003);<br></p>

<p>Applications Diethyl 4-Ethoxyphenyl-(ethyl-d5)malonate (cas# 1189708-84-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl β-Resorcylate, is a building block used for the synthesis of different pharmaceutical compounds. It can be used for the synthesis of series of CCR1 antagonists based upon spirocyclic compounds.<br>References Hossain, N., et al.: Bioorg. Med. Chem. Lett., 23, 3500 (2013);<br></p>

<p>Applications 1,2-Dimethylisothiourea-HI (cas# 41306-45-0) is a useful research chemical.<br></p>

<p>Applications N-Boc-pyrrolidine is a boc-protected cyclic amine used as a building block in the preparation of diastereomers by usually undergoing α'-lithiations and electrophilic substitution reactions.<br>References Beak, P. et al.: J. Org. Chem., 58, 1109 (1993);<br></p>

<p>Applications Used for identification of amines, and also in the synthesis and inhibition studies of substituted N-L-histidinylphenylsulfonyl hydrazide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Teng, H., et al.: Biochemistry, 38, 7363 (1999), Abdo, M., et al.: Bioorg. Med. Chem., 15, 4427 (2007),<br></p>

<p>Applications 4-Nitrophenyl Phosphorodichloridate is used as a reagent in the synthesis of dihydrobenzodioxaphosphocine oxide derivatives which have antioxidant activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siva Prasad, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2016, ahead of print)<br></p>