Building Blocks

<p>Applications O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.<br>References Sun, Y. et al.: Chin. J. CHem., 31, 1199 (2013); Akama, T. et al.: Bioorg. Med. Chem. Lett., 23, 5870 (2013);<br></p>

<p>Applications m-Toluoyl Chloride is used as a reagent in the synthesis of glycine benzamides as oral GPR139 receptor agonists. m-Toluoyl Chloride is also used in the preparation of colchicine derivatives which have potent anticancer activity and reduced P-glycoprotein induction liability.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dvorak, C.A., et al.: ACS Med. Chem. Lett., 6, 1015 (2015); Singh, B., et al.: Org. Biomol. Chem., 13, 5674 (2015)<br></p>

<p>Applications Cinnamyl Bromide acts as a reagent in the synthesis of Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keller, M., et al.: Eur. J. Med. Chem., 109, 13 (2016)<br></p>

<p>Applications N-Hydroxy-1-oxy-nicotinamidine is an intermediate in the synthesis of rac-Arimoclomol Maleic Acid (A771275), which is a potential antidiabetic agent used for the treatment of insulin resistance.<br>References Kurthy, M., et al.: PCT Int. Appl. WO 2000050403 A1 20000831. Aug 31, 2000; Kuerthy, M., et al.: Hung. Pat. Appl. HU 2000000552 A2 20011228. Dec 28, 2001<br></p>

<p>Applications 2-Iodobenzyl Alcohol (cas# 5159-41-1) is a useful research chemical.<br></p>

<p>Applications 1-(5-Bromo-2-hydroxyphenyl)ethanone<br></p>

<p>Applications Ethyl 2-Aminothiophene-3-carboxylate (cas# 31891-06-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Hydroxypropionitrile (cas# 109-78-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Nitrophenyl Phosphorodichloridate is used as a reagent in the synthesis of dihydrobenzodioxaphosphocine oxide derivatives which have antioxidant activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siva Prasad, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2016, ahead of print)<br></p>

<p>Applications Methyl β-Resorcylate, is a building block used for the synthesis of different pharmaceutical compounds. It can be used for the synthesis of series of CCR1 antagonists based upon spirocyclic compounds.<br>References Hossain, N., et al.: Bioorg. Med. Chem. Lett., 23, 3500 (2013);<br></p>

<p>Applications Methyl β,β-Dimethoxypropionate is used as a reactant in the preparation of tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents.<br>References Zheng, C., et. al.: J. Med. Chem., 57, 600 (2014)<br></p>

<p>Applications p-Vinylguaiacol-d3 is the isotope labelled analog of p-Vinylguaiacol (V424960); an aromatic substance, one of the compounds responsible for the natural aroma of buckwheat, and also one of the major pyrolytic products of (E)-N-[(4-hydroxy-3-methoxy)-phenethyl]-3-[(3-methoxy-4-O-β-D-glucopyranosyloxy) phenyl] acrylamide; a new gycloside in tobacco.<br>References Janes, Damjan., et al.: Food Chem., 112(1), 120-124 (2009); Zhou, Rong., et al.: Yancao Keji, (7), 34-36, 42 (2013)<br></p>

<p>Applications Ethyl Cyano(ethoxymethylene)acetate is an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.<br>References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);<br></p>