Building Blocks

<p>Applications Dibenzyl azodicarboxylate is a reagent used in the synthesis of Minocycline-d6 (M344797). Minocycline-d6 is a labeled second generation tetracycline antibiotic. Antibacterial.<br>References Zbinovsky, V., et al.: Anal. Profiles Drug Subs., 6, 323 (1977); Oringer, R.J., et al.: J. Periodontol., 73, 835 (2002)<br></p>

<p>Applications 2,4,6-Trichlorobenzoyl Chloride, can be used for the preparation of large-ring lactones in high yields. It is used for the syntheisis of cytotoxic marine natural product Amphidinolide X and Jasplakinolide (J210700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fieser, M. Reagents for Organic Synthesis New York 16, 353, (1992); Lepage, O., et al.: J. Amer. Chem. Scoi., 126 (49), 15970<br></p>

<p>Applications 4-Iodopyrazole is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.<br>References Northrup, A. et al.: J. Med. Chem., 56, 2294 (2013);<br></p>

<p>Applications Cinnamyl Bromide acts as a reagent in the synthesis of Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keller, M., et al.: Eur. J. Med. Chem., 109, 13 (2016)<br></p>

<p>Applications 4-Hydroxyphenylacetonitrile (cas# 14191-95-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-chloro-1-(4-chlorophenyl)ethanone (cas# 937-20-2) is a useful research chemical.<br></p>

<p>Applications 3-​Chloroiodobenzene is used in the synthesis of is a common organic reagent used i the synthesis of a prostacyclin agonist actin in the treatment of pulmonary hypertension.<br>References Tran, T. et al.: J. Med. Chem., 60, 913 (2017);<br></p>

<p>Applications 4-Chloro-2-fluoroaniline is a compound used in the synthesis of 4-Chloro-2-fluoro-3-iodobenzenamine (1000590-87-3).<br></p>

<p>Applications tert-Butyl Perbenzoate is used as a catalyst in the preparation of paper strengthening agents for papermaking.<br>References Xuan. S., et al.: Faming Zhuanli Shenqing. 6pp. (2020)<br></p>

<p>Applications trans-(1R,2R)-N,N’-Bismethyl-1,2-cyclohexanediamine is a useful research chemical for organic synthesis and other chemical processes.<br>References Bollenbach, M., et al.: Chem. Eur. J., 23, 13676 (2017); Thaisrivongs, D. A., et al.: Org. Lett., 18, 5780 (2016)<br></p>

<p>Applications Methyl 4-nitrobenzoate (cas# 619-50-1) is a useful research chemical.<br></p>

<p>Applications 2-Bromo-3'-hydroxyacetophenone (cas# 2491-37-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Bromohexadecane is used in the preparation of soluble carbon nano-onions by covalent functionalization with hexadecyl chains. It is also used to synthesize [2-(methacryloyloxy)ethyl]dimethylhexadecylammonium bromide monomer, required for the synthesis of novel methacrylate based adsorbents.<br>References Molina-Ontoria, A., et al.: Chem. Comm., 49, 2406 (2013); Shu, M., et al.: Analyst, 137, 2143 (2012)<br></p>

<p>Applications 2-BROMO-1-PHENYLPROPANE (cas# 2114-39-8) is a useful research chemical.<br></p>

<p>Applications O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.<br>References Sun, Y. et al.: Chin. J. CHem., 31, 1199 (2013); Akama, T. et al.: Bioorg. Med. Chem. Lett., 23, 5870 (2013);<br></p>

<p>Applications m-Toluoyl Chloride is used as a reagent in the synthesis of glycine benzamides as oral GPR139 receptor agonists. m-Toluoyl Chloride is also used in the preparation of colchicine derivatives which have potent anticancer activity and reduced P-glycoprotein induction liability.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dvorak, C.A., et al.: ACS Med. Chem. Lett., 6, 1015 (2015); Singh, B., et al.: Org. Biomol. Chem., 13, 5674 (2015)<br></p>