Building Blocks

<p>Applications 2,6-Dibromopyridine is used as a starting material to synthesize 2,2’-bipyridines (such as 5-Cyano-1,6-dihydro-6-oxo-[3,4'-bipyridine]-2-carboxylic Acid [C979150]) via a Stille-type cross-coupling reaction. 2,6-Dibromopyridine is also used as a reagent to synthesize pyridylpyrimidine fungicides, compounds that eliminate fungi by cycling copper through the cell membrane, where it reaches toxic levels.<br>References Hargreaves, S., et al.: Tetrahedron Lett., 41, 1653 (2000); Heller, M. &amp; Schubert, U.: J. Org. Chem., 67, 8269 (2002); Simkovsky, N., et al.: J. Chem. Soc. Perk. Trans. 1, 16, 1847 (2002)<br></p>

<p>Applications 4-Iodopyrazole is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.<br>References Northrup, A. et al.: J. Med. Chem., 56, 2294 (2013);<br></p>

<p>Applications 4-Methoxy-3-nitrobenzoic acid is a substituted nitrobenzoic acid reagent for proteomics and organic synthesis research.<br>References Achary, R. et al.: Bioorg. Med. Chem. Lett., 27, 2185 (2017);<br></p>

<p>Applications Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors.<br>References Dufer, M. et al.: Biochem. J. et al.: 15, 368 (2002); Andres, J. et al.: Bioorg. Med. Chem. Lett., 23, 785 (2013);<br></p>

<p>Applications 10,12-TRICOSADIYNOIC ACID (cas# 66990-30-5) is a useful research chemical.<br></p>

<p>Applications (E)-2-Pentenal, is a flavor volatile found in tomato, virgin olive oil and sardine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Hydroxypropionitrile (cas# 109-78-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,4-Di(bromomethyl)benzene (cas# 623-24-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Hydroxybenzamide is a secondary metabolite from marine sponge Phakellia fusca.<br>References Deng, Z., et. al.: Zhongyaocai, 36, 919 (2013)<br></p>

<p>Applications 2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols. 2-Hydroxy-5-methoxyacetophenone is also used to prepare substituted chromanone and chromone derivatives as sirtuin 2-selective inhibitors.<br>References Baker, W., et al.: J. Chem. Soc., 2303 (1948);Friden-Saxin, M., et al.: J. Med. Chem., 55, 7104 (2012)<br></p>

<p>Applications cis-2-Hexen-1-ol is used in the invention of a repellent for Oryzaephilus surinamensis.<br>References Xu, W., et al.: Faming Zhuanli Shenqing (2017), CN 107258786 A 20171020<br></p>

<p>Stability Light Sensitive<br>Applications 3-Furaldehyde is a volatile compound of honey of various floral origin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Alissandrakis, E., et al.: Food Chem., 100, 396 (2007), Baltrusaityte, V., et al.: Food Technol. Biotechnol., 45, 201 (2007),<br></p>

<p>Applications Formamidine is an intermediate used to prepare Formiminoglycine which is used in biological studies for the metabolism by purinolytic clostridia. It was also used in the synthesis of 5-methyl-4,6-dihydroxypyrimidine.<br>References Duerre, P., et al.: J. Bacteriology, 154, 192 (1983); Novais, H., et al.: J. Phys. Chem., 91, 426 (1987)<br></p>

<p>Applications Diaminomaleonitrile is a reagent used for the synthesis of 1,4-diazepine-2,3-dicarbonitrile dervatives. Also, it is used for the synthesis of Diaminomaleonitrile-based Schiff bases with a donor-acceptor structure and an aggregation-enhanced emission feature.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wieczorek, E., et al.: Tetrahedron Lett., 58, 758-761 (2017); Han, T., et al.: J. Mater. Chem. C Mater. Opt. Electron Devices, 4, 10430-10434 (2016);<br></p>

<p>Applications 2,3-Diaminophenol<br></p>

<p>Applications 1-Acetylnaphthalene is used in the preparation of S(-)-1-(1'-naphthyl) ethanol, an important synthetic intermediate of mevinic acid analog.<br>References Kamble, A.L. et al.: J. Mol. Catal. B Enzym., 35, 1 (2005); Bhattacharyya, M. et al.: Biores. Technol., 98, 1958 (2007);<br></p>

<p>Applications Boronic acid derivatives and their binding affinities with diols.<br>References Yang, W., et al.: Bioorg. Med. Chem. Lett., 12, 2175 (2002), Yang, W., et al.: Med. Res. Rev., 23, 346 (2003),<br></p>